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GLP-1 receptor agonists synergize with DYRK1A inhibitors to potentiate functional human β cell regeneration.
Ackeifi C, Wang P, Karakose E, Manning Fox JE, González BJ, Liu H, Wilson J, Swartz E, Berrouet C, Li Y, Kumar K, MacDonald PE, Sanchez R, Thorens B, DeVita R, Homann D, Egli D, Scott DK, Garcia-Ocaña A, Stewart AF. Ackeifi C, et al. Among authors: egli d. Sci Transl Med. 2020 Feb 12;12(530):eaaw9996. doi: 10.1126/scitranslmed.aaw9996. Sci Transl Med. 2020. PMID: 32051230 Free PMC article.
Combined Inhibition of DYRK1A, SMAD, and Trithorax Pathways Synergizes to Induce Robust Replication in Adult Human Beta Cells.
Wang P, Karakose E, Liu H, Swartz E, Ackeifi C, Zlatanic V, Wilson J, González BJ, Bender A, Takane KK, Ye L, Harb G, Pagliuca F, Homann D, Egli D, Argmann C, Scott DK, Garcia-Ocaña A, Stewart AF. Wang P, et al. Among authors: egli d. Cell Metab. 2019 Mar 5;29(3):638-652.e5. doi: 10.1016/j.cmet.2018.12.005. Epub 2018 Dec 20. Cell Metab. 2019. PMID: 30581122 Free PMC article.
How Safe Are Universal Pluripotent Stem Cells?
González BJ, Creusot RJ, Sykes M, Egli D. González BJ, et al. Among authors: egli d. Cell Stem Cell. 2020 Mar 5;26(3):307-308. doi: 10.1016/j.stem.2020.02.006. Cell Stem Cell. 2020. PMID: 32142661 Free PMC article. No abstract available.
How Safe Are Universal Pluripotent Stem Cells?
González BJ, Creusot RJ, Sykes M, Egli D. González BJ, et al. Among authors: egli d. Cell Stem Cell. 2020 Aug 6;27(2):346. doi: 10.1016/j.stem.2020.07.001. Cell Stem Cell. 2020. PMID: 32763183 Free PMC article. No abstract available.
Reduced calcium levels and accumulation of abnormal insulin granules in stem cell models of HNF1A deficiency.
González BJ, Zhao H, Niu J, Williams DJ, Lee J, Goulbourne CN, Xing Y, Wang Y, Oberholzer J, Blumenkrantz MH, Chen X, LeDuc CA, Chung WK, Colecraft HM, Gromada J, Shen Y, Goland RS, Leibel RL, Egli D. González BJ, et al. Among authors: egli d. Commun Biol. 2022 Aug 2;5(1):779. doi: 10.1038/s42003-022-03696-z. Commun Biol. 2022. PMID: 35918471 Free PMC article.
Toward beta cell replacement for diabetes.
Johannesson B, Sui L, Freytes DO, Creusot RJ, Egli D. Johannesson B, et al. Among authors: egli d. EMBO J. 2015 Apr 1;34(7):841-55. doi: 10.15252/embj.201490685. Epub 2015 Mar 1. EMBO J. 2015. PMID: 25733347 Free PMC article. Review.
138 results