Egli M - Search Results

1

Selective modulation of DNA polymerase activity by fixed-conformation nucleoside analogues.

Eoff RL, McGrath CE, Maddukuri L, Salamanca-Pinzón SG, Marquez VE, Marnett LJ, Guengerich FP, Egli M. Eoff RL, et al. Among authors: egli m. Angew Chem Int Ed Engl. 2010 Oct 4;49(41):7481-5. doi: 10.1002/anie.201003168. Angew Chem Int Ed Engl. 2010. PMID: 20814997 Free PMC article. No abstract available.

2

Crystal structures of B-DNA with incorporated 2'-deoxy-2'-fluoro-arabino-furanosyl thymines: implications of conformational preorganization for duplex stability.

Berger I, Tereshko V, Ikeda H, Marquez VE, Egli M. Berger I, et al. Among authors: egli m. Nucleic Acids Res. 1998 May 15;26(10):2473-80. doi: 10.1093/nar/26.10.2473. Nucleic Acids Res. 1998. PMID: 9580702 Free PMC article.

3

Direct observation of a cytosine analogue that forms five hydrogen bonds to guanosine: guanidino G-clamp.

Wilds CJ, Maier MA, Tereshko V, Manoharan M, Egli M. Wilds CJ, et al. Among authors: egli m. Angew Chem Int Ed Engl. 2002 Jan 4;41(1):115-7. doi: 10.1002/1521-3773(20020104)41:1<115::aid-anie115>3.0.co;2-r. Angew Chem Int Ed Engl. 2002. PMID: 12491456 No abstract available.

4

Why does TNA cross-pair more strongly with RNA than with DNA? an answer from X-ray analysis.

Pallan PS, Wilds CJ, Wawrzak Z, Krishnamurthy R, Eschenmoser A, Egli M. Pallan PS, et al. Among authors: egli m. Angew Chem Int Ed Engl. 2003;42(47):5893-5. doi: 10.1002/anie.200352553. Angew Chem Int Ed Engl. 2003. PMID: 14673929 No abstract available.

5

DNA adduct bypass polymerization by Sulfolobus solfataricus DNA polymerase Dpo4: analysis and crystal structures of multiple base pair substitution and frameshift products with the adduct 1,N2-ethenoguanine.

Zang H, Goodenough AK, Choi JY, Irimia A, Loukachevitch LV, Kozekov ID, Angel KC, Rizzo CJ, Egli M, Guengerich FP. Zang H, et al. Among authors: egli m. J Biol Chem. 2005 Aug 19;280(33):29750-64. doi: 10.1074/jbc.M504756200. Epub 2005 Jun 17. J Biol Chem. 2005. PMID: 15965231 Free article.

6

Efficient and high fidelity incorporation of dCTP opposite 7,8-dihydro-8-oxodeoxyguanosine by Sulfolobus solfataricus DNA polymerase Dpo4.

Zang H, Irimia A, Choi JY, Angel KC, Loukachevitch LV, Egli M, Guengerich FP. Zang H, et al. Among authors: egli m. J Biol Chem. 2006 Jan 27;281(4):2358-72. doi: 10.1074/jbc.M510889200. Epub 2005 Nov 22. J Biol Chem. 2006. PMID: 16306039 Free article.

7

Calcium is a cofactor of polymerization but inhibits pyrophosphorolysis by the Sulfolobus solfataricus DNA polymerase Dpo4.

Irimia A, Zang H, Loukachevitch LV, Eoff RL, Guengerich FP, Egli M. Irimia A, et al. Among authors: egli m. Biochemistry. 2006 May 16;45(19):5949-56. doi: 10.1021/bi052511+. Biochemistry. 2006. PMID: 16681366

8

Sulfolobus solfataricus DNA polymerase Dpo4 is partially inhibited by "wobble" pairing between O6-methylguanine and cytosine, but accurate bypass is preferred.

Eoff RL, Irimia A, Egli M, Guengerich FP. Eoff RL, et al. Among authors: egli m. J Biol Chem. 2007 Jan 12;282(2):1456-67. doi: 10.1074/jbc.M609661200. Epub 2006 Nov 14. J Biol Chem. 2007. PMID: 17105728 Free article.

9

Molecular basis of selectivity of nucleoside triphosphate incorporation opposite O6-benzylguanine by sulfolobus solfataricus DNA polymerase Dpo4: steady-state and pre-steady-state kinetics and x-ray crystallography of correct and incorrect pairing.

Eoff RL, Angel KC, Egli M, Guengerich FP. Eoff RL, et al. Among authors: egli m. J Biol Chem. 2007 May 4;282(18):13573-84. doi: 10.1074/jbc.M700656200. Epub 2007 Mar 3. J Biol Chem. 2007. PMID: 17337730 Free article.

Previous work has shown that Sulfolobus solfataricus DNA polymerase Dpo4-catalyzed bypass of O(6)-methylguanine (O(6)-MeG) proceeds largely in an accurate but inefficient manner with a "wobble" base pairing between C and O(6)-MeG (Eoff, R. L., Irimia, A., Egli, M., …

Previous work has shown that Sulfolobus solfataricus DNA polymerase Dpo4-catalyzed bypass of O(6)-methylguanine (O(6)-MeG) proceeds largely …

10

Hydrogen bonding of 7,8-dihydro-8-oxodeoxyguanosine with a charged residue in the little finger domain determines miscoding events in Sulfolobus solfataricus DNA polymerase Dpo4.

Eoff RL, Irimia A, Angel KC, Egli M, Guengerich FP. Eoff RL, et al. Among authors: egli m. J Biol Chem. 2007 Jul 6;282(27):19831-43. doi: 10.1074/jbc.M702290200. Epub 2007 Apr 27. J Biol Chem. 2007. PMID: 17468100 Free article.

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