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The PE/PPE multigene family codes for virulence factors and is a possible source of mycobacterial antigenic variation: perhaps more?
Akhter Y, Ehebauer MT, Mukhopadhyay S, Hasnain SE. Akhter Y, et al. Among authors: ehebauer mt. Biochimie. 2012 Jan;94(1):110-6. doi: 10.1016/j.biochi.2011.09.026. Epub 2011 Oct 12. Biochimie. 2012. PMID: 22005451 Review.
Active site conformational changes upon reaction intermediate biotinyl-5'-AMP binding in biotin protein ligase from Mycobacterium tuberculosis.
Ma Q, Akhter Y, Wilmanns M, Ehebauer MT. Ma Q, et al. Among authors: ehebauer mt. Protein Sci. 2014 Jul;23(7):932-9. doi: 10.1002/pro.2475. Epub 2014 Apr 22. Protein Sci. 2014. PMID: 24723382 Free PMC article.
The progress made in determining the Mycobacterium tuberculosis structural proteome.
Ehebauer MT, Wilmanns M. Ehebauer MT, et al. Proteomics. 2011 Aug;11(15):3128-33. doi: 10.1002/pmic.201000787. Epub 2011 Jun 14. Proteomics. 2011. PMID: 21674801 Free PMC article. Review.
Improved mycobacterial protein production using a Mycobacterium smegmatis groEL1ΔC expression strain.
Noens EE, Williams C, Anandhakrishnan M, Poulsen C, Ehebauer MT, Wilmanns M. Noens EE, et al. Among authors: ehebauer mt. BMC Biotechnol. 2011 Mar 25;11:27. doi: 10.1186/1472-6750-11-27. BMC Biotechnol. 2011. PMID: 21439037 Free PMC article.
The structural and functional determinants of the Axin and Dishevelled DIX domains.
Ehebauer MT, Arias AM. Ehebauer MT, et al. BMC Struct Biol. 2009 Nov 12;9:70. doi: 10.1186/1472-6807-9-70. BMC Struct Biol. 2009. PMID: 19909509 Free PMC article.
Characterization of the mycobacterial acyl-CoA carboxylase holo complexes reveals their functional expansion into amino acid catabolism.
Ehebauer MT, Zimmermann M, Jakobi AJ, Noens EE, Laubitz D, Cichocki B, Marrakchi H, Lanéelle MA, Daffé M, Sachse C, Dziembowski A, Sauer U, Wilmanns M. Ehebauer MT, et al. PLoS Pathog. 2015 Feb 19;11(2):e1004623. doi: 10.1371/journal.ppat.1004623. eCollection 2015 Feb. PLoS Pathog. 2015. PMID: 25695631 Free PMC article.
High-resolution crystal structure of the human Notch 1 ankyrin domain.
Ehebauer MT, Chirgadze DY, Hayward P, Martinez Arias A, Blundell TL. Ehebauer MT, et al. Biochem J. 2005 Nov 15;392(Pt 1):13-20. doi: 10.1042/BJ20050515. Biochem J. 2005. PMID: 16011479 Free PMC article.
Notch signaling pathway.
Ehebauer M, Hayward P, Martinez-Arias A. Ehebauer M, et al. Sci STKE. 2006 Dec 5;2006(364):cm7. doi: 10.1126/stke.3642006cm7. Sci STKE. 2006. PMID: 17148788 Review.
Using a fragment-based approach to target protein-protein interactions.
Scott DE, Ehebauer MT, Pukala T, Marsh M, Blundell TL, Venkitaraman AR, Abell C, Hyvönen M. Scott DE, et al. Among authors: ehebauer mt. Chembiochem. 2013 Feb 11;14(3):332-42. doi: 10.1002/cbic.201200521. Epub 2013 Jan 23. Chembiochem. 2013. PMID: 23344974 Free PMC article.
Small molecule inhibitors of RAS-effector protein interactions derived using an intracellular antibody fragment.
Quevedo CE, Cruz-Migoni A, Bery N, Miller A, Tanaka T, Petch D, Bataille CJR, Lee LYW, Fallon PS, Tulmin H, Ehebauer MT, Fernandez-Fuentes N, Russell AJ, Carr SB, Phillips SEV, Rabbitts TH. Quevedo CE, et al. Among authors: ehebauer mt. Nat Commun. 2018 Aug 9;9(1):3169. doi: 10.1038/s41467-018-05707-2. Nat Commun. 2018. PMID: 30093669 Free PMC article.
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