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Craniocervical instability in patients with Ehlers-Danlos syndrome: controversies in diagnosis and management.
Mao G, Kopparapu S, Jin Y, Davidar AD, Hersh AM, Weber-Levine C, Theodore N. Mao G, et al. Spine J. 2022 Dec;22(12):1944-1952. doi: 10.1016/j.spinee.2022.08.008. Epub 2022 Aug 24. Spine J. 2022. PMID: 36028216 Review.
Ehlers-Danlos syndrome (EDS) is a rare hereditary condition that can result in ligamentous laxity and hypermobility of the cervical spine. A subset of patients can develop clinical instability of the craniocervical junction associated with pain and neu …
Ehlers-Danlos syndrome (EDS) is a rare hereditary condition that can result in ligamentous laxity and hypermobility of the cer …
Craniocervical Instability in Ehlers-Danlos Syndrome-A Systematic Review of Diagnostic and Surgical Treatment Criteria.
Lohkamp LN, Marathe N, Fehlings MG. Lohkamp LN, et al. Global Spine J. 2022 Oct;12(8):1862-1871. doi: 10.1177/21925682211068520. Epub 2022 Feb 23. Global Spine J. 2022. PMID: 35195459 Free PMC article. Review.
STUDY DESIGN: Systematic review. OBJECTIVE: Ehlers-Danlos Syndrome (EDS) comprises a spectrum of connective tissue disorders, which may be associated with cranio-cervical instability (CCI). ...Surgical fixation of suspected CCI should only be performed in cas …
STUDY DESIGN: Systematic review. OBJECTIVE: Ehlers-Danlos Syndrome (EDS) comprises a spectrum of connective tissue disorders, …
Respiratory manifestations in the Ehlers-Danlos syndromes.
Bascom R, Dhingra R, Francomano CA. Bascom R, et al. Am J Med Genet C Semin Med Genet. 2021 Dec;187(4):533-548. doi: 10.1002/ajmg.c.31953. Epub 2021 Nov 22. Am J Med Genet C Semin Med Genet. 2021. PMID: 34811894 Review.
Persons with the Ehlers-Danlos syndromes (EDS) report a wide range of respiratory symptoms, most commonly shortness of breath, exercise limitation, and cough. ...Inflammatory manifestations include costochondritis, bronchiectasis, and localized respiratory allergic …
Persons with the Ehlers-Danlos syndromes (EDS) report a wide range of respiratory symptoms, most commonly shortness of breath, …
Neurological and spinal manifestations of the Ehlers-Danlos syndromes.
Henderson FC Sr, Austin C, Benzel E, Bolognese P, Ellenbogen R, Francomano CA, Ireton C, Klinge P, Koby M, Long D, Patel S, Singman EL, Voermans NC. Henderson FC Sr, et al. Am J Med Genet C Semin Med Genet. 2017 Mar;175(1):195-211. doi: 10.1002/ajmg.c.31549. Epub 2017 Feb 21. Am J Med Genet C Semin Med Genet. 2017. PMID: 28220607 Review.
The Ehlers-Danlos syndromes (EDS) are a heterogeneous group of heritable connective tissue disorders characterized by joint hypermobility, skin extensibility, and tissue fragility. ...Chiari Malformation Type I (CMI) has been reported to be a comorbid condition to E …
The Ehlers-Danlos syndromes (EDS) are a heterogeneous group of heritable connective tissue disorders characterized by joint hy …
Craniocervical instability in patients with Ehlers-Danlos syndromes: outcomes analysis following occipito-cervical fusion of published cases.
Mughal ZUN, Malik A. Mughal ZUN, et al. Neurosurg Rev. 2024 Apr 16;47(1):158. doi: 10.1007/s10143-024-02395-z. Neurosurg Rev. 2024. PMID: 38625445
This critique provides a critical analysis of the outcomes following occipito-cervical fusion in patients with Ehlers-Danlos syndromes (EDS) and craniocervical instability. The study examines the efficacy of the surgical intervention and evaluates its …
This critique provides a critical analysis of the outcomes following occipito-cervical fusion in patients with Ehlers-Danlos s …
Craniocervical instability in patients with Ehlers-Danlos syndromes: outcomes analysis following occipito-cervical fusion.
Henderson FC Sr, Schubart JR, Narayanan MV, Tuchman K, Mills SE, Poppe DJ, Koby MB, Rowe PC, Francomano CA. Henderson FC Sr, et al. Neurosurg Rev. 2024 Jan 2;47(1):27. doi: 10.1007/s10143-023-02249-0. Neurosurg Rev. 2024. PMID: 38163828 Free PMC article.
Craniocervical instability (CCI) is increasingly recognized in hereditary disorders of connective tissue and in some patients following suboccipital decompression for Chiari malformation (CMI) or low-lying cerebellar tonsils (LLCT). ...We conducted a retrospective a …
Craniocervical instability (CCI) is increasingly recognized in hereditary disorders of connective tissue and in some patients …
Perioperative opioid-minimization approach as a useful protocol in the management of patients with Ehlers-Danlos syndrome-hypermobility type, craniocervical instability and severe chronic pain who are to undergo occipito-cervical fixation.
Ramírez-Paesano C, Rodiera Clarens C, Sharp Segovia A, Coila Bustinza A, Rodiera Olive J, Juanola Galceran A. Ramírez-Paesano C, et al. Orphanet J Rare Dis. 2023 Jul 25;18(1):214. doi: 10.1186/s13023-023-02829-9. Orphanet J Rare Dis. 2023. PMID: 37491286 Free PMC article. Review.
Patients suffering from connective tissue disorders like Ehlers-Danlos syndrome hypermobility type/joint hypermobility syndrome (EDS-HT/JHS) may be affected by craniocervical instability (CCI). ...
Patients suffering from connective tissue disorders like Ehlers-Danlos syndrome hypermobility type/joint hypermobility syndrom …
Co-occurrence of tethered cord syndrome and cervical spine instability in hypermobile Ehlers-Danlos syndrome.
Gensemer C, Daylor V, Nix J, Norris RA, Patel S. Gensemer C, et al. Front Neurol. 2024 Jul 17;15:1441866. doi: 10.3389/fneur.2024.1441866. eCollection 2024. Front Neurol. 2024. PMID: 39087018 Free PMC article.
The Ehlers-Danlos Syndromes (EDS) represent a group of hereditary connective tissue disorders, with the hypermobile subtype (hEDS) being the most prevalent. hEDS manifests with a diverse array of clinical symptoms and associated comorbidities spanning the musculoske …
The Ehlers-Danlos Syndromes (EDS) represent a group of hereditary connective tissue disorders, with the hypermobile subtype (h …
Presentation and physical therapy management of upper cervical instability in patients with symptomatic generalized joint hypermobility: International expert consensus recommendations.
Russek LN, Block NP, Byrne E, Chalela S, Chan C, Comerford M, Frost N, Hennessey S, McCarthy A, Nicholson LL, Parry J, Simmonds J, Stott PJ, Thomas L, Treleaven J, Wagner W, Hakim A. Russek LN, et al. Front Med (Lausanne). 2023 Jan 18;9:1072764. doi: 10.3389/fmed.2022.1072764. eCollection 2022. Front Med (Lausanne). 2023. PMID: 36743665 Free PMC article.
Experts in symptomatic generalized joint hypermobility (S-GJH) agree that upper cervical instability (UCI) needs to be better recognized in S-GJH, which commonly presents in the clinic as generalized hypermobility spectrum disorder and hypermobile Ehlers-Danlos …
Experts in symptomatic generalized joint hypermobility (S-GJH) agree that upper cervical instability (UCI) needs to be better recogni …
Ehlers-Danlos syndrome-associated craniocervical instability with cervicomedullary syndrome: Comparing outcome of craniocervical fusion with occipital bone versus occipital condyle fixation.
Spiessberger A, Dietz N, Gruter B, Virojanapa J. Spiessberger A, et al. J Craniovertebr Junction Spine. 2020 Oct-Dec;11(4):287-292. doi: 10.4103/jcvjs.JCVJS_166_20. Epub 2020 Nov 26. J Craniovertebr Junction Spine. 2020. PMID: 33824558 Free PMC article.
INTRODUCTION: Ehlers-Danlos syndrome (EDS) predisposes to craniocervical instability (CCI) with resulting cranial settling and cervicomedullary syndrome due to ligamentous laxity. This study investigates possible differences in radiographic outcomes an …
INTRODUCTION: Ehlers-Danlos syndrome (EDS) predisposes to craniocervical instability (CCI) with resulting crania …
41 results