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Overexpression of the 'silencer of death domain', SODD/BAG-4, modulates both TNFR1- and CD95-dependent cell death pathways.
Eichholtz-Wirth H, Fritz E, Wolz L. Eichholtz-Wirth H, et al. Cancer Lett. 2003 May 8;194(1):81-9. doi: 10.1016/s0304-3835(03)00009-0. Cancer Lett. 2003. PMID: 12706861
Enhanced CD95-mediated apoptosis contributes to radiation hypersensitivity of NBS lymphoblasts.
Sagan D, Mörtl S, Müller I, Eckardt-Schupp F, Eichholtz-Wirth H. Sagan D, et al. Among authors: eichholtz wirth h. Apoptosis. 2007 Apr;12(4):753-67. doi: 10.1007/s10495-006-0021-0. Apoptosis. 2007. PMID: 17219051
Reduced expression of the ICE-related protease CPP32 is associated with radiation-induced cisplatin resistance in HeLa cells.
Eichholtz-Wirth H, Stoetzer O, Marx K. Eichholtz-Wirth H, et al. Br J Cancer. 1997;76(10):1322-7. doi: 10.1038/bjc.1997.555. Br J Cancer. 1997. PMID: 9374378 Free PMC article.
Radiation-induced transient cisplatin resistance in murine fibrosarcoma cells associated with elevated metallothionein content.
Eichholtz-Wirth H, Reidel G, Hietel B. Eichholtz-Wirth H, et al. Br J Cancer. 1993 May;67(5):1001-6. doi: 10.1038/bjc.1993.183. Br J Cancer. 1993. PMID: 8494693 Free PMC article.
Reversal of radiation-induced cisplatin resistance in murine fibrosarcoma cells by selective modulation of the cyclic GMP-dependent transduction pathway.
Eichholtz-Wirth H. Eichholtz-Wirth H. Br J Cancer. 1995 Aug;72(2):287-92. doi: 10.1038/bjc.1995.326. Br J Cancer. 1995. PMID: 7640207 Free PMC article.
Cisplatin resistance in mouse fibrosarcoma cells after low-dose irradiation in vitro and in vivo.
Eichholtz-Wirth H, Hietel B. Eichholtz-Wirth H, et al. Br J Cancer. 1994 Oct;70(4):579-84. doi: 10.1038/bjc.1994.354. Br J Cancer. 1994. PMID: 7522509 Free PMC article.
Altered signaling of TNFalpha-TNFR1 and SODD/BAG4 is responsible for radioresistance in human HT-R15 cells.
Eichholtz-Wirth H, Sagan D. Eichholtz-Wirth H, et al. Anticancer Res. 2002 Jan-Feb;22(1A):235-40. Anticancer Res. 2002. PMID: 12017295
IkappaB/NF-kappaB mediated cisplatin resistance in HeLa cells after low-dose gamma-irradiation is associated with altered SODD expression.
Eichholtz-Wirth H, Sagan D. Eichholtz-Wirth H, et al. Apoptosis. 2000 Jun;5(3):255-63. doi: 10.1023/a:1009656513307. Apoptosis. 2000. PMID: 11225847
Dual function of membrane-bound heat shock protein 70 (Hsp70), Bag-4, and Hsp40: protection against radiation-induced effects and target structure for natural killer cells.
Gehrmann M, Marienhagen J, Eichholtz-Wirth H, Fritz E, Ellwart J, Jäättelä M, Zilch T, Multhoff G. Gehrmann M, et al. Among authors: eichholtz wirth h. Cell Death Differ. 2005 Jan;12(1):38-51. doi: 10.1038/sj.cdd.4401510. Cell Death Differ. 2005. PMID: 15592361 Free article.
Clonal variability of radiation-induced cisplatin resistant HeLa cells.
Eichholtz-Wirth H, Marx K. Eichholtz-Wirth H, et al. Anticancer Res. 1998 Jul-Aug;18(4C):2989-91. Anticancer Res. 1998. PMID: 9713497
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