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Contributions of Myc to tumorigenesis.
Lutz W, Leon J, Eilers M. Lutz W, et al. Biochim Biophys Acta. 2002 Mar 14;1602(1):61-71. doi: 10.1016/s0304-419x(02)00036-7. Biochim Biophys Acta. 2002. PMID: 11960695 Review.
Association with Aurora-A Controls N-MYC-Dependent Promoter Escape and Pause Release of RNA Polymerase II during the Cell Cycle.
Büchel G, Carstensen A, Mak KY, Roeschert I, Leen E, Sumara O, Hofstetter J, Herold S, Kalb J, Baluapuri A, Poon E, Kwok C, Chesler L, Maric HM, Rickman DS, Wolf E, Bayliss R, Walz S, Eilers M. Büchel G, et al. Cell Rep. 2017 Dec 19;21(12):3483-3497. doi: 10.1016/j.celrep.2017.11.090. Cell Rep. 2017. PMID: 29262328 Free PMC article.
TEAD activity is restrained by MYC and stratifies human breast cancer subtypes.
Elster D, Jaenicke LA, Eilers M, von Eyss B. Elster D, et al. Cell Cycle. 2016 Oct;15(19):2551-2556. doi: 10.1080/15384101.2016.1207837. Epub 2016 Jul 19. Cell Cycle. 2016. PMID: 27433809 Free PMC article.
The role of MIZ-1 in MYC-dependent tumorigenesis.
Wiese KE, Walz S, von Eyss B, Wolf E, Athineos D, Sansom O, Eilers M. Wiese KE, et al. Cold Spring Harb Perspect Med. 2013 Dec 1;3(12):a014290. doi: 10.1101/cshperspect.a014290. Cold Spring Harb Perspect Med. 2013. PMID: 24296348 Free PMC article. Review.
The MYC mRNA 3'-UTR couples RNA polymerase II function to glutamine and ribonucleotide levels.
Dejure FR, Royla N, Herold S, Kalb J, Walz S, Ade CP, Mastrobuoni G, Vanselow JT, Schlosser A, Wolf E, Kempa S, Eilers M. Dejure FR, et al. EMBO J. 2017 Jul 3;36(13):1854-1868. doi: 10.15252/embj.201796662. Epub 2017 Apr 13. EMBO J. 2017. PMID: 28408437 Free PMC article.
MYC and tumor metabolism: chicken and egg.
Dejure FR, Eilers M. Dejure FR, et al. EMBO J. 2017 Dec 1;36(23):3409-3420. doi: 10.15252/embj.201796438. Epub 2017 Nov 10. EMBO J. 2017. PMID: 29127156 Free PMC article. Review.
The MK5/PRAK kinase and Myc form a negative feedback loop that is disrupted during colorectal tumorigenesis.
Kress TR, Cannell IG, Brenkman AB, Samans B, Gaestel M, Roepman P, Burgering BM, Bushell M, Rosenwald A, Eilers M. Kress TR, et al. Mol Cell. 2011 Feb 18;41(4):445-57. doi: 10.1016/j.molcel.2011.01.023. Mol Cell. 2011. PMID: 21329882
Myc increases self-renewal in neural progenitor cells through Miz-1.
Kerosuo L, Piltti K, Fox H, Angers-Loustau A, Häyry V, Eilers M, Sariola H, Wartiovaara K. Kerosuo L, et al. J Cell Sci. 2008 Dec 1;121(Pt 23):3941-50. doi: 10.1242/jcs.024802. Epub 2008 Nov 11. J Cell Sci. 2008. PMID: 19001505
Small molecule inhibitors of aurora-a induce proteasomal degradation of N-myc in childhood neuroblastoma.
Brockmann M, Poon E, Berry T, Carstensen A, Deubzer HE, Rycak L, Jamin Y, Thway K, Robinson SP, Roels F, Witt O, Fischer M, Chesler L, Eilers M. Brockmann M, et al. Cancer Cell. 2013 Jul 8;24(1):75-89. doi: 10.1016/j.ccr.2013.05.005. Epub 2013 Jun 20. Cancer Cell. 2013. PMID: 23792191 Free PMC article.
Inflammation-induced NFATc1-STAT3 transcription complex promotes pancreatic cancer initiation by KrasG12D.
Baumgart S, Chen NM, Siveke JT, König A, Zhang JS, Singh SK, Wolf E, Bartkuhn M, Esposito I, Heßmann E, Reinecke J, Nikorowitsch J, Brunner M, Singh G, Fernandez-Zapico ME, Smyrk T, Bamlet WR, Eilers M, Neesse A, Gress TM, Billadeau DD, Tuveson D, Urrutia R, Ellenrieder V. Baumgart S, et al. Cancer Discov. 2014 Jun;4(6):688-701. doi: 10.1158/2159-8290.CD-13-0593. Epub 2014 Apr 2. Cancer Discov. 2014. PMID: 24694735 Free PMC article.
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