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Coincidental loss of DOCK8 function in NLRP10-deficient and C3H/HeJ mice results in defective dendritic cell migration.
Krishnaswamy JK, Singh A, Gowthaman U, Wu R, Gorrepati P, Sales Nascimento M, Gallman A, Liu D, Rhebergen AM, Calabro S, Xu L, Ranney P, Srivastava A, Ranson M, Gorham JD, McCaw Z, Kleeberger SR, Heinz LX, Müller AC, Bennett KL, Superti-Furga G, Henao-Mejia J, Sutterwala FS, Williams A, Flavell RA, Eisenbarth SC. Krishnaswamy JK, et al. Among authors: eisenbarth sc. Proc Natl Acad Sci U S A. 2015 Mar 10;112(10):3056-61. doi: 10.1073/pnas.1501554112. Epub 2015 Feb 23. Proc Natl Acad Sci U S A. 2015. PMID: 25713392 Free PMC article.
Food-specific immunoglobulin A does not correlate with natural tolerance to peanut or egg allergens.
Liu EG, Zhang B, Martin V, Anthonypillai J, Kraft M, Grishin A, Grishina G, Catanzaro JR, Chinthrajah S, Sindher T, Manohar M, Quake AZ, Nadeau K, Burks AW, Kim EH, Kulis MD, Henning AK, Jones SM, Leung DYM, Sicherer SH, Wood RA, Yuan Q, Shreffler W, Sampson H, Shabanova V, Eisenbarth SC. Liu EG, et al. Among authors: eisenbarth sc. Sci Transl Med. 2022 Nov 16;14(671):eabq0599. doi: 10.1126/scitranslmed.abq0599. Epub 2022 Nov 16. Sci Transl Med. 2022. PMID: 36383680 Free PMC article.
Antibody-mediated antigen loss switches augmented immunity to antibody-mediated immunosuppression.
Jajosky RP, Patel KR, Allen JWL, Zerra PE, Chonat S, Ayona D, Maier CL, Morais D, Wu SC, Luckey CJ, Eisenbarth SC, Roback JD, Fasano RM, Josephson CD, Manis JP, Chai L, Hendrickson JE, Hudson KE, Arthur CM, Stowell SR. Jajosky RP, et al. Among authors: eisenbarth sc. Blood. 2023 Sep 21;142(12):1082-1098. doi: 10.1182/blood.2022018591. Blood. 2023. PMID: 37363865
The Nalp3 inflammasome is essential for the development of silicosis.
Cassel SL, Eisenbarth SC, Iyer SS, Sadler JJ, Colegio OR, Tephly LA, Carter AB, Rothman PB, Flavell RA, Sutterwala FS. Cassel SL, et al. Among authors: eisenbarth sc. Proc Natl Acad Sci U S A. 2008 Jul 1;105(26):9035-40. doi: 10.1073/pnas.0803933105. Epub 2008 Jun 24. Proc Natl Acad Sci U S A. 2008. PMID: 18577586 Free PMC article.
Inflammasome-activating nanoparticles as modular systems for optimizing vaccine efficacy.
Demento SL, Eisenbarth SC, Foellmer HG, Platt C, Caplan MJ, Mark Saltzman W, Mellman I, Ledizet M, Fikrig E, Flavell RA, Fahmy TM. Demento SL, et al. Among authors: eisenbarth sc. Vaccine. 2009 May 18;27(23):3013-21. doi: 10.1016/j.vaccine.2009.03.034. Epub 2009 Apr 3. Vaccine. 2009. PMID: 19428913 Free PMC article.
It has recently been shown that one member of an intracellular PRR, the NLRP3 inflammasome, is activated by a number of classical adjuvants including aluminum hydroxide and saponins [Eisenbarth SC, Colegio OR, O'Connor W, Sutterwala FS, Flavell RA. Crucial role for …
It has recently been shown that one member of an intracellular PRR, the NLRP3 inflammasome, is activated by a number of classical adjuvants …
Malarial hemozoin activates the NLRP3 inflammasome through Lyn and Syk kinases.
Shio MT, Eisenbarth SC, Savaria M, Vinet AF, Bellemare MJ, Harder KW, Sutterwala FS, Bohle DS, Descoteaux A, Flavell RA, Olivier M. Shio MT, et al. Among authors: eisenbarth sc. PLoS Pathog. 2009 Aug;5(8):e1000559. doi: 10.1371/journal.ppat.1000559. Epub 2009 Aug 21. PLoS Pathog. 2009. PMID: 19696895 Free PMC article.
Necrotic cells trigger a sterile inflammatory response through the Nlrp3 inflammasome.
Iyer SS, Pulskens WP, Sadler JJ, Butter LM, Teske GJ, Ulland TK, Eisenbarth SC, Florquin S, Flavell RA, Leemans JC, Sutterwala FS. Iyer SS, et al. Among authors: eisenbarth sc. Proc Natl Acad Sci U S A. 2009 Dec 1;106(48):20388-93. doi: 10.1073/pnas.0908698106. Epub 2009 Nov 16. Proc Natl Acad Sci U S A. 2009. PMID: 19918053 Free PMC article.
98 results