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Activation of extracellular signal-regulated kinase (ERK)1/2 contributes to cytokine-induced apoptosis in purified rat pancreatic beta-cells.
Pavlovic D, Andersen NA, Mandrup-Poulsen T, Eizirik DL. Pavlovic D, et al. Among authors: eizirik dl. Eur Cytokine Netw. 2000 Jun;11(2):267-74. Eur Cytokine Netw. 2000. PMID: 10903806
Interleukin-1 beta increases the activity of superoxide dismutase in rat pancreatic islets.
Borg LA, Cagliero E, Sandler S, Welsh N, Eizirik DL. Borg LA, et al. Among authors: eizirik dl. Endocrinology. 1992 May;130(5):2851-7. doi: 10.1210/endo.130.5.1533363. Endocrinology. 1992. PMID: 1533363
Long term in vitro effects of streptozotocin, interleukin-1, and high glucose concentration on the activity of mitochondrial dehydrogenases and the secretion of insulin in pancreatic islets.
Rasschaert J, Eizirik DL, Malaisse WJ. Rasschaert J, et al. Among authors: eizirik dl. Endocrinology. 1992 Jun;130(6):3522-8. doi: 10.1210/endo.130.6.1534541. Endocrinology. 1992. PMID: 1534541
Role of receptor binding and gene transcription for both the stimulatory and inhibitory effects of interleukin-1 in pancreatic beta-cells.
Eizirik DL, Tracey DE, Bendtzen K, Sandler S. Eizirik DL, et al. Autoimmunity. 1992;12(2):127-33. doi: 10.3109/08916939209150319. Autoimmunity. 1992. PMID: 1535517
Liposomal delivery of purified heat shock protein hsp70 into rat pancreatic islets as protection against interleukin 1 beta-induced impaired beta-cell function.
Margulis BA, Sandler S, Eizirik DL, Welsh N, Welsh M. Margulis BA, et al. Among authors: eizirik dl. Diabetes. 1991 Nov;40(11):1418-22. doi: 10.2337/diab.40.11.1418. Diabetes. 1991. PMID: 1936603
Short exposure of rat pancreatic islets to interleukin-1 beta induces a sustained but reversible impairment in beta-cell function: influence of protease activation, gene transcription, and protein synthesis.
Eizirik DL, Bendtzen K, Sandler S. Eizirik DL, et al. Endocrinology. 1991 Mar;128(3):1611-6. doi: 10.1210/endo-128-3-1611. Endocrinology. 1991. PMID: 1999175
Dissociation between interleukin-1 beta-induced expression of mRNA for superoxide dismutase and nitric oxide synthase in insulin-producing cells.
Bigdeli N, Niemann A, Sandler S, Eizirik DL. Bigdeli N, et al. Among authors: eizirik dl. Biochem Biophys Res Commun. 1994 Sep 30;203(3):1542-7. doi: 10.1006/bbrc.1994.2361. Biochem Biophys Res Commun. 1994. PMID: 7524486
Interleukin-1 beta-induced stimulation of insulin release in mouse pancreatic islets is related to diacylglycerol production and protein kinase C activation.
Eizirik DL, Sandler S, Welsh N, Juntti-Berggren L, Berggren PO. Eizirik DL, et al. Mol Cell Endocrinol. 1995 Jun;111(2):159-65. doi: 10.1016/0303-7207(95)03561-k. Mol Cell Endocrinol. 1995. PMID: 7556877
Insulin-like growth factor I does not inhibit insulin secretion in adult human pancreatic islets in tissue culture.
Eizirik DL, Skottner A, Hellerström C. Eizirik DL, et al. Eur J Endocrinol. 1995 Aug;133(2):248-50. doi: 10.1530/eje.0.1330248. Eur J Endocrinol. 1995. PMID: 7655651
SAM prevents impairment of glucose-stimulated insulin secretion caused by hexose deprivation or starvation.
Conget I, Zhang TM, Eizirik DL, Malaisse WJ. Conget I, et al. Among authors: eizirik dl. Am J Physiol. 1995 Apr;268(4 Pt 1):E580-7. doi: 10.1152/ajpendo.1995.268.4.E580. Am J Physiol. 1995. PMID: 7733255
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