Eizirik DL - Search Results

1

Exposure to the viral by-product dsRNA or Coxsackievirus B5 triggers pancreatic beta cell apoptosis via a Bim / Mcl-1 imbalance.

Colli ML, Nogueira TC, Allagnat F, Cunha DA, Gurzov EN, Cardozo AK, Roivainen M, Op de Beeck A, Eizirik DL. Colli ML, et al. Among authors: eizirik dl. PLoS Pathog. 2011 Sep;7(9):e1002267. doi: 10.1371/journal.ppat.1002267. Epub 2011 Sep 22. PLoS Pathog. 2011. PMID: 21977009 Free PMC article.

2

Mechanisms of coxsackievirus-induced damage to human pancreatic beta-cells.

Roivainen M, Rasilainen S, Ylipaasto P, Nissinen R, Ustinov J, Bouwens L, Eizirik DL, Hovi T, Otonkoski T. Roivainen M, et al. Among authors: eizirik dl. J Clin Endocrinol Metab. 2000 Jan;85(1):432-40. doi: 10.1210/jcem.85.1.6306. J Clin Endocrinol Metab. 2000. PMID: 10634421

3

Identification of novel cytokine-induced genes in pancreatic beta-cells by high-density oligonucleotide arrays.

Cardozo AK, Kruhøffer M, Leeman R, Orntoft T, Eizirik DL. Cardozo AK, et al. Among authors: eizirik dl. Diabetes. 2001 May;50(5):909-20. doi: 10.2337/diabetes.50.5.909. Diabetes. 2001. PMID: 11334433

4

Inhibition of cytokine-induced NF-kappaB activation by adenovirus-mediated expression of a NF-kappaB super-repressor prevents beta-cell apoptosis.

Heimberg H, Heremans Y, Jobin C, Leemans R, Cardozo AK, Darville M, Eizirik DL. Heimberg H, et al. Among authors: eizirik dl. Diabetes. 2001 Oct;50(10):2219-24. doi: 10.2337/diabetes.50.10.2219. Diabetes. 2001. PMID: 11574401

5

A comprehensive analysis of cytokine-induced and nuclear factor-kappa B-dependent genes in primary rat pancreatic beta-cells.

Cardozo AK, Heimberg H, Heremans Y, Leeman R, Kutlu B, Kruhøffer M, Ørntoft T, Eizirik DL. Cardozo AK, et al. Among authors: eizirik dl. J Biol Chem. 2001 Dec 28;276(52):48879-86. doi: 10.1074/jbc.M108658200. Epub 2001 Oct 30. J Biol Chem. 2001. PMID: 11687580 Free article.

6

Double-stranded RNA cooperates with interferon-gamma and IL-1 beta to induce both chemokine expression and nuclear factor-kappa B-dependent apoptosis in pancreatic beta-cells: potential mechanisms for viral-induced insulitis and beta-cell death in type 1 diabetes mellitus.

Liu D, Cardozo AK, Darville MI, Eizirik DL. Liu D, et al. Among authors: eizirik dl. Endocrinology. 2002 Apr;143(4):1225-34. doi: 10.1210/endo.143.4.8737. Endocrinology. 2002. PMID: 11897677

7

Molecular regulation of monocyte chemoattractant protein-1 expression in pancreatic beta-cells.

Kutlu B, Darville MI, Cardozo AK, Eizirik DL. Kutlu B, et al. Among authors: eizirik dl. Diabetes. 2003 Feb;52(2):348-55. doi: 10.2337/diabetes.52.2.348. Diabetes. 2003. PMID: 12540607

8

IL-1beta and IFN-gamma induce the expression of diverse chemokines and IL-15 in human and rat pancreatic islet cells, and in islets from pre-diabetic NOD mice.

Cardozo AK, Proost P, Gysemans C, Chen MC, Mathieu C, Eizirik DL. Cardozo AK, et al. Among authors: eizirik dl. Diabetologia. 2003 Feb;46(2):255-66. doi: 10.1007/s00125-002-1017-0. Epub 2003 Feb 12. Diabetologia. 2003. PMID: 12627325

9

Discovery of gene networks regulating cytokine-induced dysfunction and apoptosis in insulin-producing INS-1 cells.

Kutlu B, Cardozo AK, Darville MI, Kruhøffer M, Magnusson N, Ørntoft T, Eizirik DL. Kutlu B, et al. Among authors: eizirik dl. Diabetes. 2003 Nov;52(11):2701-19. doi: 10.2337/diabetes.52.11.2701. Diabetes. 2003. PMID: 14578289

10

Gene microarray study corroborates proteomic findings in rodent islet cells.

Cardozo AK, Berthou L, Kruhøffer M, Orntoft T, Nicolls MR, Eizirik DL. Cardozo AK, et al. Among authors: eizirik dl. J Proteome Res. 2003 Sep-Oct;2(5):553-5. doi: 10.1021/pr034029o. J Proteome Res. 2003. PMID: 14582652

To address this issue, we presently compared data from mouse primary islet proteins obtained by proteomic analysis with RNA data from FACS purified primary rat beta cells obtained by microarray analysis (Rasschaert J, Liu D, Cardozo AK, Kutlu B, Eizirik DL, manuscri …

To address this issue, we presently compared data from mouse primary islet proteins obtained by proteomic analysis with RNA data from FACS p …

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