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266 results
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Therapeutic targeting of the angiopoietin-TIE pathway.
Saharinen P, Eklund L, Alitalo K. Saharinen P, et al. Among authors: eklund l. Nat Rev Drug Discov. 2017 Sep;16(9):635-661. doi: 10.1038/nrd.2016.278. Epub 2017 May 19. Nat Rev Drug Discov. 2017. PMID: 28529319 Review.
VEGFR3 Modulates Vascular Permeability by Controlling VEGF/VEGFR2 Signaling.
Heinolainen K, Karaman S, D'Amico G, Tammela T, Sormunen R, Eklund L, Alitalo K, Zarkada G. Heinolainen K, et al. Among authors: eklund l. Circ Res. 2017 Apr 28;120(9):1414-1425. doi: 10.1161/CIRCRESAHA.116.310477. Epub 2017 Mar 15. Circ Res. 2017. PMID: 28298294 Free PMC article.
Tie1 deletion inhibits tumor growth and improves angiopoietin antagonist therapy.
D'Amico G, Korhonen EA, Anisimov A, Zarkada G, Holopainen T, Hägerling R, Kiefer F, Eklund L, Sormunen R, Elamaa H, Brekken RA, Adams RH, Koh GY, Saharinen P, Alitalo K. D'Amico G, et al. Among authors: eklund l. J Clin Invest. 2014 Feb;124(2):824-34. doi: 10.1172/JCI68897. Epub 2014 Jan 16. J Clin Invest. 2014. PMID: 24430181 Free PMC article.
Angiopoietin signaling in the vasculature.
Eklund L, Saharinen P. Eklund L, et al. Exp Cell Res. 2013 May 15;319(9):1271-80. doi: 10.1016/j.yexcr.2013.03.011. Epub 2013 Mar 13. Exp Cell Res. 2013. PMID: 23500414 Review.
Effects of angiopoietin-2-blocking antibody on endothelial cell-cell junctions and lung metastasis.
Holopainen T, Saharinen P, D'Amico G, Lampinen A, Eklund L, Sormunen R, Anisimov A, Zarkada G, Lohela M, Heloterä H, Tammela T, Benjamin LE, Ylä-Herttuala S, Leow CC, Koh GY, Alitalo K. Holopainen T, et al. Among authors: eklund l. J Natl Cancer Inst. 2012 Mar 21;104(6):461-75. doi: 10.1093/jnci/djs009. Epub 2012 Feb 17. J Natl Cancer Inst. 2012. PMID: 22343031 Free PMC article.
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