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Ligand requirements for immunoreceptor triggering.
Barton MI, Paterson RL, Denham EM, Goyette J, van der Merwe PA. Barton MI, et al. Among authors: denham em. Commun Biol. 2024 Sep 13;7(1):1138. doi: 10.1038/s42003-024-06817-y. Commun Biol. 2024. PMID: 39271744 Free PMC article.
Using CombiCells, a platform for titration and combinatorial display of cell surface ligands, to study T-cell antigen sensitivity modulation by accessory receptors.
Patel A, Andre V, Eguiguren SB, Barton MI, Burton J, Denham EM, Pettmann J, Mørch AM, Kutuzov MA, Siller-Farfán JA, Dustin ML, van der Merwe PA, Dushek O. Patel A, et al. Among authors: denham em. EMBO J. 2024 Jan;43(1):132-150. doi: 10.1038/s44318-023-00012-1. Epub 2023 Dec 18. EMBO J. 2024. PMID: 38177315 Free PMC article.
Conserved allomorphs of MR1 drive the specificity of MR1-restricted TCRs.
Cornforth TV, Moyo N, Cole S, Lam EPS, Lobry T, Wolchinsky R, Lloyd A, Ward K, Denham EM, Masi G, Qing Yun PT, Moore C, Dhaouadi S, Besra GS, Veerapen N, Illing PT, Vivian JP, Raynes JM, Le Nours J, Purcell AW, Kundu S, Silk JD, Williams L, Papa S, Rossjohn J, Howie D, Dukes J. Cornforth TV, et al. Among authors: denham em. Front Oncol. 2024 Oct 3;14:1419528. doi: 10.3389/fonc.2024.1419528. eCollection 2024. Front Oncol. 2024. PMID: 39445059 Free PMC article.