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Pathophysiology of articular chondrocalcinosis--role of ANKH.
Abhishek A, Doherty M. Abhishek A, et al. Nat Rev Rheumatol. 2011 Feb;7(2):96-104. doi: 10.1038/nrrheum.2010.182. Epub 2010 Nov 23. Nat Rev Rheumatol. 2011. PMID: 21102543 Review.
Elevated levels of synovial fluid pyrophosphate promote CPP crystal formation. This extracellular pyrophosphate originates either from the breakdown of nucleotide triphosphates by plasma-cell membrane glycoprotein 1 (PC-1) or from pyrophosphate
Elevated levels of synovial fluid pyrophosphate promote CPP crystal formation. This extracellular pyrophosphate origina
Plasma levels of platelet secretory proteins.
Kaplan KL, Owen J. Kaplan KL, et al. Crit Rev Oncol Hematol. 1986;5(3):235-55. doi: 10.1016/s1040-8428(86)80040-3. Crit Rev Oncol Hematol. 1986. PMID: 2427239 Review.
Most of the proteins secreted from platelets are stored in the alpha granules, whereas the dense granules contain substances such as adenine nucleotides, serotonin, Ca++, and inorganic pyrophosphate types as well as a heparatinase. Three of the secreted alpha granule prote …
Most of the proteins secreted from platelets are stored in the alpha granules, whereas the dense granules contain substances such as adenine …
Coenzyme Q10 in phenylketonuria and mevalonic aciduria.
Hargreaves IP. Hargreaves IP. Mitochondrion. 2007 Jun;7 Suppl:S175-80. doi: 10.1016/j.mito.2007.02.009. Epub 2007 Mar 16. Mitochondrion. 2007. PMID: 17442628 Review.
Although evidence of a lowered plasma/serum CoQ10 level has been reported in MVA and PKU, few studies have assessed the intracellular CoQ10 concentration of patients. Plasma/serum CoQ10 is influenced by dietary intake as well as its lipoprotein content and therefore …
Although evidence of a lowered plasma/serum CoQ10 level has been reported in MVA and PKU, few studies have assessed the intracellular …
Earlier diagnosis and treatment of acute myocardial infarction necessitates the need for a 'new diagnostic mind-set'.
Roberts R, Kleiman NS. Roberts R, et al. Circulation. 1994 Feb;89(2):872-81. doi: 10.1161/01.cir.89.2.872. Circulation. 1994. PMID: 8313577 Review.
Triaging patients suspected of myocardial infarction is performed primarily in the coronary care unit, with infarction determined within 12 to 24 hours, and only about 20% are subsequently shown to have myocardial infarction. Plasma MB CK is not elevated until 8 to …
Triaging patients suspected of myocardial infarction is performed primarily in the coronary care unit, with infarction determined within 12 …
Inorganic pyrophosphate metabolism in arthritis.
Rachow JW, Ryan LM. Rachow JW, et al. Rheum Dis Clin North Am. 1988 Aug;14(2):289-302. Rheum Dis Clin North Am. 1988. PMID: 2845490 Review.
Documented roles include participation in intracellular Ca++ traffic, mediation of nucleotide and iron transport, storage of molecules in cellular granules, modification of enzyme function, and modulation of mineralization. Much has been established regarding plasma, urine …
Documented roles include participation in intracellular Ca++ traffic, mediation of nucleotide and iron transport, storage of molecules in ce …