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Signaling pathways initiated by beta-hydroxy-beta-methylbutyrate to attenuate the depression of protein synthesis in skeletal muscle in response to cachectic stimuli.
Eley HL, Russell ST, Baxter JH, Mukerji P, Tisdale MJ. Eley HL, et al. Am J Physiol Endocrinol Metab. 2007 Oct;293(4):E923-31. doi: 10.1152/ajpendo.00314.2007. Epub 2007 Jul 3. Am J Physiol Endocrinol Metab. 2007. PMID: 17609254 Free article.
Role of reactive oxygen species in protein degradation in murine myotubes induced by proteolysis-inducing factor and angiotensin II.
Russell ST, Eley H, Tisdale MJ. Russell ST, et al. Among authors: eley h. Cell Signal. 2007 Aug;19(8):1797-806. doi: 10.1016/j.cellsig.2007.04.003. Epub 2007 Apr 19. Cell Signal. 2007. PMID: 17532611
Mechanism of attenuation of angiotensin-II-induced protein degradation by insulin-like growth factor-I (IGF-I).
Russell ST, Eley H, Tisdale MJ. Russell ST, et al. Among authors: eley h. Cell Signal. 2007 Jul;19(7):1583-95. doi: 10.1016/j.cellsig.2007.02.005. Epub 2007 Feb 21. Cell Signal. 2007. PMID: 17376652
Mechanism of activation of dsRNA-dependent protein kinase (PKR) in muscle atrophy.
Eley HL, Russell ST, Tisdale MJ. Eley HL, et al. Cell Signal. 2010 May;22(5):783-90. doi: 10.1016/j.cellsig.2010.01.002. Epub 2010 Jan 13. Cell Signal. 2010. PMID: 20074639
Role of the dsRNA-dependent protein kinase (PKR) in the attenuation of protein loss from muscle by insulin and insulin-like growth factor-I (IGF-I).
Eley HL, Russell ST, Tisdale MJ. Eley HL, et al. Mol Cell Biochem. 2008 Jun;313(1-2):63-9. doi: 10.1007/s11010-008-9742-4. Epub 2008 Mar 23. Mol Cell Biochem. 2008. PMID: 18360789
Attenuation of muscle atrophy in a murine model of cachexia by inhibition of the dsRNA-dependent protein kinase.
Eley HL, Russell ST, Tisdale MJ. Eley HL, et al. Br J Cancer. 2007 Apr 23;96(8):1216-22. doi: 10.1038/sj.bjc.6603704. Epub 2007 Mar 27. Br J Cancer. 2007. PMID: 17387345 Free PMC article.
Increased expression of phosphorylated forms of RNA-dependent protein kinase and eukaryotic initiation factor 2alpha may signal skeletal muscle atrophy in weight-losing cancer patients.
Eley HL, Skipworth RJ, Deans DA, Fearon KC, Tisdale MJ. Eley HL, et al. Br J Cancer. 2008 Jan 29;98(2):443-9. doi: 10.1038/sj.bjc.6604150. Epub 2007 Dec 18. Br J Cancer. 2008. PMID: 18087277 Free PMC article.
Attenuation of depression of muscle protein synthesis induced by lipopolysaccharide, tumor necrosis factor, and angiotensin II by beta-hydroxy-beta-methylbutyrate.
Eley HL, Russell ST, Tisdale MJ. Eley HL, et al. Am J Physiol Endocrinol Metab. 2008 Dec;295(6):E1409-16. doi: 10.1152/ajpendo.90530.2008. Epub 2008 Oct 14. Am J Physiol Endocrinol Metab. 2008. PMID: 18854427 Free article.
Mechanism of attenuation of muscle protein degradation induced by tumor necrosis factor-alpha and angiotensin II by beta-hydroxy-beta-methylbutyrate.
Eley HL, Russell ST, Tisdale MJ. Eley HL, et al. Am J Physiol Endocrinol Metab. 2008 Dec;295(6):E1417-26. doi: 10.1152/ajpendo.90567.2008. Epub 2008 Oct 7. Am J Physiol Endocrinol Metab. 2008. PMID: 18840762 Free article.
Inhibition of activation of dsRNA-dependent protein kinase and tumour growth inhibition.
Eley HL, McDonald PS, Russell ST, Tisdale MJ. Eley HL, et al. Cancer Chemother Pharmacol. 2009 Mar;63(4):651-9. doi: 10.1007/s00280-008-0782-y. Epub 2008 Jun 14. Cancer Chemother Pharmacol. 2009. PMID: 18553083
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