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Cilia and disease.
Eley L, Yates LM, Goodship JA. Eley L, et al. Curr Opin Genet Dev. 2005 Jun;15(3):308-14. doi: 10.1016/j.gde.2005.04.008. Curr Opin Genet Dev. 2005. PMID: 15917207 Review.
Expression analyses and interaction with the anaphase promoting complex protein Apc2 suggest a role for inversin in primary cilia and involvement in the cell cycle.
Morgan D, Eley L, Sayer J, Strachan T, Yates LM, Craighead AS, Goodship JA. Morgan D, et al. Among authors: eley l. Hum Mol Genet. 2002 Dec 15;11(26):3345-50. doi: 10.1093/hmg/11.26.3345. Hum Mol Genet. 2002. PMID: 12471060
A perspective on inversin.
Eley L, Turnpenny L, Yates LM, Craighead AS, Morgan D, Whistler C, Goodship JA, Strachan T. Eley L, et al. Cell Biol Int. 2004;28(2):119-24. doi: 10.1016/j.cellbi.2003.11.009. Cell Biol Int. 2004. PMID: 14984757 Review.
The splanchnic mesodermal plate directs spleen and pancreatic laterality, and is regulated by Bapx1/Nkx3.2.
Hecksher-Sørensen J, Watson RP, Lettice LA, Serup P, Eley L, De Angelis C, Ahlgren U, Hill RE. Hecksher-Sørensen J, et al. Among authors: eley l. Development. 2004 Oct;131(19):4665-75. doi: 10.1242/dev.01364. Epub 2004 Aug 25. Development. 2004. PMID: 15329346
Urinary concentration defects and mechanisms underlying nephronophthisis.
Krishnan R, Eley L, Sayer JA. Krishnan R, et al. Among authors: eley l. Kidney Blood Press Res. 2008;31(3):152-62. doi: 10.1159/000129648. Epub 2008 May 6. Kidney Blood Press Res. 2008. PMID: 18460874 Review.
Jouberin localizes to collecting ducts and interacts with nephrocystin-1.
Eley L, Gabrielides C, Adams M, Johnson CA, Hildebrandt F, Sayer JA. Eley L, et al. Kidney Int. 2008 Nov;74(9):1139-49. doi: 10.1038/ki.2008.377. Epub 2008 Jul 16. Kidney Int. 2008. PMID: 18633336
The pyrophosphate transporter ANKH is expressed in kidney and bone cells and colocalises to the primary cilium/basal body complex.
Carr G, Moochhala SH, Eley L, Vandewalle A, Simmons NL, Sayer JA. Carr G, et al. Among authors: eley l. Cell Physiol Biochem. 2009;24(5-6):595-604. doi: 10.1159/000257515. Epub 2009 Nov 4. Cell Physiol Biochem. 2009. PMID: 19910700
Modelling a ciliopathy: Ahi1 knockdown in model systems reveals an essential role in brain, retinal, and renal development.
Simms RJ, Hynes AM, Eley L, Inglis D, Chaudhry B, Dawe HR, Sayer JA. Simms RJ, et al. Among authors: eley l. Cell Mol Life Sci. 2012 Mar;69(6):993-1009. doi: 10.1007/s00018-011-0826-z. Epub 2011 Sep 29. Cell Mol Life Sci. 2012. PMID: 21959375
Investigating embryonic expression patterns and evolution of AHI1 and CEP290 genes, implicated in Joubert syndrome.
Cheng YZ, Eley L, Hynes AM, Overman LM, Simms RJ, Barker A, Dawe HR, Lindsay S, Sayer JA. Cheng YZ, et al. Among authors: eley l. PLoS One. 2012;7(9):e44975. doi: 10.1371/journal.pone.0044975. Epub 2012 Sep 24. PLoS One. 2012. PMID: 23028714 Free PMC article.
Nephronophthisis.
Simms RJ, Eley L, Sayer JA. Simms RJ, et al. Among authors: eley l. Eur J Hum Genet. 2009 Apr;17(4):406-16. doi: 10.1038/ejhg.2008.238. Epub 2008 Dec 10. Eur J Hum Genet. 2009. PMID: 19066617 Free PMC article.
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