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Page 1
Unconventional initiation of PINK1/Parkin mitophagy by Optineurin.
Nguyen TN, Sawa-Makarska J, Khuu G, Lam WK, Adriaenssens E, Fracchiolla D, Shoebridge S, Bernklau D, Padman BS, Skulsuppaisarn M, Lindblom RSJ, Martens S, Lazarou M. Nguyen TN, et al. Among authors: adriaenssens e. Mol Cell. 2023 May 18;83(10):1693-1709.e9. doi: 10.1016/j.molcel.2023.04.021. Mol Cell. 2023. PMID: 37207627 Free article.
Control of mitophagy initiation and progression by the TBK1 adaptors NAP1 and SINTBAD.
Adriaenssens E, Nguyen TN, Sawa-Makarska J, Khuu G, Schuschnig M, Shoebridge S, Skulsuppaisarn M, Watts EM, Csalyi KD, Padman BS, Lazarou M, Martens S. Adriaenssens E, et al. Nat Struct Mol Biol. 2024 Nov;31(11):1717-1731. doi: 10.1038/s41594-024-01338-y. Epub 2024 Jun 25. Nat Struct Mol Biol. 2024. PMID: 38918639 Free PMC article.
HSPB8 frameshift mutant aggregates weaken chaperone-assisted selective autophagy in neuromyopathies.
Tedesco B, Vendredy L, Adriaenssens E, Cozzi M, Asselbergh B, Crippa V, Cristofani R, Rusmini P, Ferrari V, Casarotto E, Chierichetti M, Mina F, Pramaggiore P, Galbiati M, Piccolella M, Baets J, Baeke F, De Rycke R, Mouly V, Laurenzi T, Eberini I, Vihola A, Udd B, Weiss L, Kimonis V, Timmerman V, Poletti A. Tedesco B, et al. Among authors: adriaenssens e. Autophagy. 2023 Aug;19(8):2217-2239. doi: 10.1080/15548627.2023.2179780. Epub 2023 Feb 28. Autophagy. 2023. PMID: 36854646 Free PMC article.
Small heat shock proteins in neurodegenerative diseases.
Vendredy L, Adriaenssens E, Timmerman V. Vendredy L, et al. Among authors: adriaenssens e. Cell Stress Chaperones. 2020 Jul;25(4):679-699. doi: 10.1007/s12192-020-01101-4. Epub 2020 Apr 22. Cell Stress Chaperones. 2020. PMID: 32323160 Free PMC article. Review.
Reconstitution of BNIP3/NIX-mediated autophagy reveals two pathways and hierarchical flexibility of the initiation machinery.
Adriaenssens E, Schaar S, Cook ASI, Stuke JFM, Sawa-Makarska J, Nguyen TN, Ren X, Schuschnig M, Romanov J, Khuu G, Lazarou M, Hummer G, Hurley JH, Martens S. Adriaenssens E, et al. bioRxiv [Preprint]. 2024 Aug 28:2024.08.28.609967. doi: 10.1101/2024.08.28.609967. bioRxiv. 2024. Update in: Nat Cell Biol. 2025 Aug;27(8):1272-1287. doi: 10.1038/s41556-025-01712-y. PMID: 39253418 Free PMC article. Updated. Preprint.
Reconstitution of multistep recruitment of ULK1 to membranes in autophagy.
Duan Y, Lu Y, Paul S, Betz J, Wilhelm L, Cook ASI, Ren X, Adriaenssens E, Martens S, Ganley IG, Hummer G, Hurley JH. Duan Y, et al. Among authors: adriaenssens e. bioRxiv [Preprint]. 2025 Nov 9:2025.11.07.687251. doi: 10.1101/2025.11.07.687251. bioRxiv. 2025. PMID: 41278708 Free PMC article. Preprint.
24 results