Primary HIV infection features colonic damage and neutrophil inflammation yet containment of microbial translocation.
Tincati C, Bono V, Cannizzo ES, Tosi D, Savi F, Falcinella C, Casabianca A, Orlandi C, Luigiano C, Augello M, Rusconi S, Muscatello A, Bandera A, Calcagno A, Gori A, Nozza S, Marchetti G; on behalf of the Italian Network of ACuTe HIV InfectiON (INACTION).
Tincati C, et al.
AIDS. 2024 Apr 1;38(5):623-632. doi: 10.1097/QAD.0000000000003799. Epub 2023 Dec 4.
AIDS. 2024.
PMID: 38016163
Free PMC article.
In plasma, we measured microbial translocation (LPS, sCD14, EndoCAb) and gut barrier function (I-FABP) markers (ELISA). RESULTS: P-HIV displayed significantly higher tissue HIV DNA, yet neutrophil infiltration and collagen deposition in the gut were similar in the two grou …
In plasma, we measured microbial translocation (LPS, sCD14, EndoCAb) and gut barrier function (I-FABP) markers (ELISA). RESULTS: P-HI …