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BRCA1 as tumor suppressor: lord without its RING?
Elia AE, Elledge SJ. Elia AE, et al. Among authors: elledge sj. Breast Cancer Res. 2012 Apr 10;14(2):306. doi: 10.1186/bcr3118. Breast Cancer Res. 2012. PMID: 22494569 Free PMC article.
DNA damage-induced activation of p53 by the checkpoint kinase Chk2.
Hirao A, Kong YY, Matsuoka S, Wakeham A, Ruland J, Yoshida H, Liu D, Elledge SJ, Mak TW. Hirao A, et al. Among authors: elledge sj. Science. 2000 Mar 10;287(5459):1824-7. doi: 10.1126/science.287.5459.1824. Science. 2000. PMID: 10710310
Ataxia telangiectasia-mutated phosphorylates Chk2 in vivo and in vitro.
Matsuoka S, Rotman G, Ogawa A, Shiloh Y, Tamai K, Elledge SJ. Matsuoka S, et al. Among authors: elledge sj. Proc Natl Acad Sci U S A. 2000 Sep 12;97(19):10389-94. doi: 10.1073/pnas.190030497. Proc Natl Acad Sci U S A. 2000. PMID: 10973490 Free PMC article.
Chk2 is a tumor suppressor that regulates apoptosis in both an ataxia telangiectasia mutated (ATM)-dependent and an ATM-independent manner.
Hirao A, Cheung A, Duncan G, Girard PM, Elia AJ, Wakeham A, Okada H, Sarkissian T, Wong JA, Sakai T, De Stanchina E, Bristow RG, Suda T, Lowe SW, Jeggo PA, Elledge SJ, Mak TW. Hirao A, et al. Among authors: elledge sj. Mol Cell Biol. 2002 Sep;22(18):6521-32. doi: 10.1128/MCB.22.18.6521-6532.2002. Mol Cell Biol. 2002. PMID: 12192050 Free PMC article.
378 results