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53 results

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Page 1
Microbial metabolite indole-3-propionic acid drives mitochondrial respiration in CD4+ T cells to confer protection against intestinal inflammation.
Li Q, de Oliveira Formiga R, Puchois V, Creusot L, Ahmad AH, Amouyal S, Campos-Ribeiro MA, Zhao Y, Harris DMM, Lasserre F, Ellero-Simatos S, Guillou H, Huang Z, Brot L, Hu Y, Chollet L, Danne C, Scandola C, Ledent T, Chevreux G, Argüello RJ, De Carvalho Bittencourt M, Bettinger J, D'Aveni-Piney M, Moulin D, Schreiber S, Aden K, Rolhion N, Michel ML, Wai T, Sokol H. Li Q, et al. Among authors: ellero simatos s. Nat Metab. 2025 Dec;7(12):2510-2530. doi: 10.1038/s42255-025-01396-6. Epub 2025 Oct 21. Nat Metab. 2025. PMID: 41120706 Free PMC article.
Integrative study of diet-induced mouse models of NAFLD identifies PPARα as a sexually dimorphic drug target.
Smati S, Polizzi A, Fougerat A, Ellero-Simatos S, Blum Y, Lippi Y, Régnier M, Laroyenne A, Huillet M, Arif M, Zhang C, Lasserre F, Marrot A, Al Saati T, Wan J, Sommer C, Naylies C, Batut A, Lukowicz C, Fougeray T, Tramunt B, Dubot P, Smith L, Bertrand-Michel J, Hennuyer N, Pradere JP, Staels B, Burcelin R, Lenfant F, Arnal JF, Levade T, Gamet-Payrastre L, Lagarrigue S, Loiseau N, Lotersztajn S, Postic C, Wahli W, Bureau C, Guillaume M, Mardinoglu A, Montagner A, Gourdy P, Guillou H. Smati S, et al. Among authors: ellero simatos s. Gut. 2022 Apr;71(4):807-821. doi: 10.1136/gutjnl-2020-323323. Epub 2021 Apr 26. Gut. 2022. PMID: 33903148 Free article.
ATGL-dependent white adipose tissue lipolysis controls hepatocyte PPARα activity.
Fougerat A, Schoiswohl G, Polizzi A, Régnier M, Wagner C, Smati S, Fougeray T, Lippi Y, Lasserre F, Raho I, Melin V, Tramunt B, Métivier R, Sommer C, Benhamed F, Alkhoury C, Greulich F, Jouffe C, Emile A, Schupp M, Gourdy P, Dubot P, Levade T, Meynard D, Ellero-Simatos S, Gamet-Payrastre L, Panasyuk G, Uhlenhaut H, Amri EZ, Cruciani-Guglielmacci C, Postic C, Wahli W, Loiseau N, Montagner A, Langin D, Lass A, Guillou H. Fougerat A, et al. Among authors: ellero simatos s. Cell Rep. 2022 Jun 7;39(10):110910. doi: 10.1016/j.celrep.2022.110910. Cell Rep. 2022. PMID: 35675775 Free article.
The interplay between dietary fatty acids and gut microbiota influences host metabolism and hepatic steatosis.
Schoeler M, Ellero-Simatos S, Birkner T, Mayneris-Perxachs J, Olsson L, Brolin H, Loeber U, Kraft JD, Polizzi A, Martí-Navas M, Puig J, Moschetta A, Montagner A, Gourdy P, Heymes C, Guillou H, Tremaroli V, Fernández-Real JM, Forslund SK, Burcelin R, Caesar R. Schoeler M, et al. Among authors: ellero simatos s. Nat Commun. 2023 Sep 1;14(1):5329. doi: 10.1038/s41467-023-41074-3. Nat Commun. 2023. PMID: 37658064 Free PMC article.
Obesity promotes fumonisin B1 hepatotoxicity.
Dopavogui L, Régnier M, Polizzi A, Ponchon Q, Smati S, Klement W, Lasserre F, Lukowicz C, Lippi Y, Fougerat A, Bertrand-Michel J, Naylies C, Canlet C, Debrauwer L, Rousseau-Bacquié E, Gamet-Payrastre L, Dauriat C, Casas J, Croubels S, De Baere S, Burger HM, Chassaing B, Ellero-Simatos S, Guillou H, Oswald IP, Loiseau N. Dopavogui L, et al. Among authors: ellero simatos s. Sci Total Environ. 2023 Sep 15;891:164436. doi: 10.1016/j.scitotenv.2023.164436. Epub 2023 May 27. Sci Total Environ. 2023. PMID: 37247733 Free article.
Thermoneutral housing worsens MASLD and reveals defective brown adipose tissue response to β3-adrenergic stimulation.
Martin CMP, Polizzi A, Alquier-Bacquié V, Huillet M, Rives C, Dauriat CJG, Bruse J, Melin V, Naylies C, Lippi Y, Lasserre F, Wan J, Flores-Flores R, Bertrand-Michel J, Blas-Y-Estrada F, Rousseau-Bacquié E, Levade T, Rémignon H, Langin D, Mouisel E, Lotersztajn S, Chassaing B, Gamet-Payrastre L, Guillou H, Ellero-Simatos S, Fougerat A, Loiseau N. Martin CMP, et al. Among authors: ellero simatos s. iScience. 2025 Jul 26;28(9):113221. doi: 10.1016/j.isci.2025.113221. eCollection 2025 Sep 19. iScience. 2025. PMID: 40894885 Free PMC article.
Liver gene expression and its rewiring in hepatic steatosis are controlled by PI3Kα-dependent hepatocyte signaling.
Régnier M, Polizzi A, Fougeray T, Fougerat A, Perrier P, Anderson K, Lippi Y, Smati S, Lukowicz C, Lasserre F, Fouche E, Huillet M, Rives C, Tramunt B, Naylies C, Garcia G, Rousseau-Bacquié E, Bertrand-Michel J, Canlet C, Chevolleau-Mege S, Debrauwer L, Heymes C, Burcelin R, Levade T, Gourdy P, Wahli W, Blum Y, Gamet-Payrastre L, Ellero-Simatos S, Guillermet-Guibert J, Hawkins P, Stephens L, Postic C, Montagner A, Loiseau N, Guillou H. Régnier M, et al. Among authors: ellero simatos s. PLoS Biol. 2025 Apr 14;23(4):e3003112. doi: 10.1371/journal.pbio.3003112. eCollection 2025 Apr. PLoS Biol. 2025. PMID: 40228209 Free PMC article.
Triggering tumorigenic signaling: Succinate dehydrogenase inhibitor (SDHi) fungicides induce oncometabolite accumulation and metabolic shift in human colon cells.
Duarte Hospital C, Tête A, Debizet K, Rives C, Imler J, Safi-Stibler S, Gales L, Bellvert F, Dairou J, Hagimont A, Burel A, Lagadic-Gossmann D, Barouki R, Shay JW, Bastin J, Mouillet-Richard S, Lemarié A, Djouadi F, Ellero-Simatos S, Coumoul X, Favier J, Bortoli S. Duarte Hospital C, et al. Among authors: ellero simatos s. Environ Int. 2025 May;199:109503. doi: 10.1016/j.envint.2025.109503. Epub 2025 May 2. Environ Int. 2025. PMID: 40359599 Free article.
Fructose malabsorption induces cholecystokinin expression in the ileum and cecum by changing microbiota composition and metabolism.
Zhang X, Grosfeld A, Williams E, Vasiliauskas D, Barretto S, Smith L, Mariadassou M, Philippe C, Devime F, Melchior C, Gourcerol G, Dourmap N, Lapaque N, Larraufie P, Blottière HM, Herberden C, Gerard P, Rehfeld JF, Ferraris RP, Fritton JC, Ellero-Simatos S, Douard V. Zhang X, et al. Among authors: ellero simatos s. FASEB J. 2019 Jun;33(6):7126-7142. doi: 10.1096/fj.201801526RR. Epub 2019 Apr 2. FASEB J. 2019. PMID: 30939042 Free PMC article.
53 results