Ellinghaus P - Search Results

1

Mimicking hypoxia to treat anemia: HIF-stabilizer BAY 85-3934 (Molidustat) stimulates erythropoietin production without hypertensive effects.

Flamme I, Oehme F, Ellinghaus P, Jeske M, Keldenich J, Thuss U. Flamme I, et al. Among authors: ellinghaus p. PLoS One. 2014 Nov 13;9(11):e111838. doi: 10.1371/journal.pone.0111838. eCollection 2014. PLoS One. 2014. PMID: 25392999 Free PMC article.

2

FGF23 expression in rodents is directly induced via erythropoietin after inhibition of hypoxia inducible factor proline hydroxylase.

Flamme I, Ellinghaus P, Urrego D, Krüger T. Flamme I, et al. Among authors: ellinghaus p. PLoS One. 2017 Oct 26;12(10):e0186979. doi: 10.1371/journal.pone.0186979. eCollection 2017. PLoS One. 2017. PMID: 29073196 Free PMC article.

3

Overexpression of PH-4, a novel putative proline 4-hydroxylase, modulates activity of hypoxia-inducible transcription factors.

Oehme F, Ellinghaus P, Kolkhof P, Smith TJ, Ramakrishnan S, Hütter J, Schramm M, Flamme I. Oehme F, et al. Among authors: ellinghaus p. Biochem Biophys Res Commun. 2002 Aug 16;296(2):343-9. doi: 10.1016/s0006-291x(02)00862-8. Biochem Biophys Res Commun. 2002. PMID: 12163023

4

BAY 87-2243, a highly potent and selective inhibitor of hypoxia-induced gene activation has antitumor activities by inhibition of mitochondrial complex I.

Ellinghaus P, Heisler I, Unterschemmann K, Haerter M, Beck H, Greschat S, Ehrmann A, Summer H, Flamme I, Oehme F, Thierauch K, Michels M, Hess-Stumpp H, Ziegelbauer K. Ellinghaus P, et al. Cancer Med. 2013 Oct;2(5):611-24. doi: 10.1002/cam4.112. Epub 2013 Aug 20. Cancer Med. 2013. PMID: 24403227 Free PMC article.

5

Rogaratinib: A potent and selective pan-FGFR inhibitor with broad antitumor activity in FGFR-overexpressing preclinical cancer models.

Grünewald S, Politz O, Bender S, Héroult M, Lustig K, Thuss U, Kneip C, Kopitz C, Zopf D, Collin MP, Boemer U, Ince S, Ellinghaus P, Mumberg D, Hess-Stumpp H, Ziegelbauer K. Grünewald S, et al. Among authors: ellinghaus p. Int J Cancer. 2019 Sep 1;145(5):1346-1357. doi: 10.1002/ijc.32224. Epub 2019 Mar 13. Int J Cancer. 2019. PMID: 30807645 Free PMC article.

6

Inhibition of hypoxia-induced gene transcription by substituted pyrazolyl oxadiazoles: initial lead generation and structure-activity relationships.

Härter M, Thierauch KH, Boyer S, Bhargava A, Ellinghaus P, Beck H, Greschat-Schade S, Hess-Stumpp H, Unterschemmann K. Härter M, et al. Among authors: ellinghaus p. ChemMedChem. 2014 Jan;9(1):61-6. doi: 10.1002/cmdc.201300357. Epub 2013 Nov 27. ChemMedChem. 2014. PMID: 24285584

7

18F-FAZA PET imaging response tracks the reoxygenation of tumors in mice upon treatment with the mitochondrial complex I inhibitor BAY 87-2243.

Chang E, Liu H, Unterschemmann K, Ellinghaus P, Liu S, Gekeler V, Cheng Z, Berndorff D, Gambhir SS. Chang E, et al. Among authors: ellinghaus p. Clin Cancer Res. 2015 Jan 15;21(2):335-46. doi: 10.1158/1078-0432.CCR-14-0217. Epub 2014 Nov 7. Clin Cancer Res. 2015. PMID: 25381339 Free PMC article.

8

A role for coagulation factor Xa in experimental pulmonary arterial hypertension.

Delbeck M, Nickel KF, Perzborn E, Ellinghaus P, Strassburger J, Kast R, Laux V, Schäfer S, Schermuly RT, von Degenfeld G. Delbeck M, et al. Among authors: ellinghaus p. Cardiovasc Res. 2011 Oct 1;92(1):159-68. doi: 10.1093/cvr/cvr168. Epub 2011 Jun 15. Cardiovasc Res. 2011. PMID: 21676958

9

Regorafenib (BAY 73-4506): antitumor and antimetastatic activities in preclinical models of colorectal cancer.

Schmieder R, Hoffmann J, Becker M, Bhargava A, Müller T, Kahmann N, Ellinghaus P, Adams R, Rosenthal A, Thierauch KH, Scholz A, Wilhelm SM, Zopf D. Schmieder R, et al. Among authors: ellinghaus p. Int J Cancer. 2014 Sep 15;135(6):1487-96. doi: 10.1002/ijc.28669. Epub 2014 Apr 17. Int J Cancer. 2014. PMID: 24347491 Free PMC article.

10

Combined tyrosine and serine/threonine kinase inhibition by sorafenib prevents progression of experimental pulmonary hypertension and myocardial remodeling.

Klein M, Schermuly RT, Ellinghaus P, Milting H, Riedl B, Nikolova S, Pullamsetti SS, Weissmann N, Dony E, Savai R, Ghofrani HA, Grimminger F, Busch AE, Schäfer S. Klein M, et al. Among authors: ellinghaus p. Circulation. 2008 Nov 11;118(20):2081-90. doi: 10.1161/CIRCULATIONAHA.108.779751. Epub 2008 Oct 27. Circulation. 2008. PMID: 18955668

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