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Safe, efficient, and reproducible gene therapy of the brain in the dog models of Sanfilippo and Hurler syndromes.
Ellinwood NM, Ausseil J, Desmaris N, Bigou S, Liu S, Jens JK, Snella EM, Mohammed EE, Thomson CB, Raoul S, Joussemet B, Roux F, Chérel Y, Lajat Y, Piraud M, Benchaouir R, Hermening S, Petry H, Froissart R, Tardieu M, Ciron C, Moullier P, Parkes J, Kline KL, Maire I, Vanier MT, Heard JM, Colle MA. Ellinwood NM, et al. Mol Ther. 2011 Feb;19(2):251-9. doi: 10.1038/mt.2010.265. Epub 2010 Dec 7. Mol Ther. 2011. PMID: 21139569 Free PMC article.
The RPGRIP1-deficient dog, a promising canine model for gene therapy.
Lhériteau E, Libeau L, Stieger K, Deschamps JY, Mendes-Madeira A, Provost N, Lemoine F, Mellersh C, Ellinwood NM, Cherel Y, Moullier P, Rolling F. Lhériteau E, et al. Among authors: ellinwood nm. Mol Vis. 2009;15:349-61. Epub 2009 Feb 18. Mol Vis. 2009. PMID: 19223988 Free PMC article.
Early versus late treatment of spinal cord compression with long-term intrathecal enzyme replacement therapy in canine mucopolysaccharidosis type I.
Dickson PI, Hanson S, McEntee MF, Vite CH, Vogler CA, Mlikotic A, Chen AH, Ponder KP, Haskins ME, Tippin BL, Le SQ, Passage MB, Guerra C, Dierenfeld A, Jens J, Snella E, Kan SH, Ellinwood NM. Dickson PI, et al. Among authors: ellinwood nm. Mol Genet Metab. 2010 Oct-Nov;101(2-3):115-22. doi: 10.1016/j.ymgme.2010.06.020. Epub 2010 Jul 23. Mol Genet Metab. 2010. PMID: 20655780 Free PMC article.
Normal canine brain maturation at magnetic resonance imaging.
Gross B, Garcia-Tapia D, Riedesel E, Ellinwood NM, Jens JK. Gross B, et al. Among authors: ellinwood nm. Vet Radiol Ultrasound. 2010 Jul-Aug;51(4):361-73. doi: 10.1111/j.1740-8261.2010.01681.x. Vet Radiol Ultrasound. 2010. PMID: 20806866 Free PMC article.
Replacing the enzyme alpha-L-iduronidase at birth ameliorates symptoms in the brain and periphery of dogs with mucopolysaccharidosis type I.
Dierenfeld AD, McEntee MF, Vogler CA, Vite CH, Chen AH, Passage M, Le S, Shah S, Jens JK, Snella EM, Kline KL, Parkes JD, Ware WA, Moran LE, Fales-Williams AJ, Wengert JA, Whitley RD, Betts DM, Boal AM, Riedesel EA, Gross W, Ellinwood NM, Dickson PI. Dierenfeld AD, et al. Among authors: ellinwood nm. Sci Transl Med. 2010 Dec 1;2(60):60ra89. doi: 10.1126/scitranslmed.3001380. Sci Transl Med. 2010. PMID: 21123810 Free PMC article.
74 results