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Tumor cell escape from therapy-induced senescence.
Saleh T, Tyutyunyk-Massey L, Murray GF, Alotaibi MR, Kawale AS, Elsayed Z, Henderson SC, Yakovlev V, Elmore LW, Toor A, Harada H, Reed J, Landry JW, Gewirtz DA. Saleh T, et al. Among authors: elsayed z. Biochem Pharmacol. 2019 Apr;162:202-212. doi: 10.1016/j.bcp.2018.12.013. Epub 2018 Dec 19. Biochem Pharmacol. 2019. PMID: 30576620
BPTF inhibits NK cell activity and the abundance of natural cytotoxicity receptor co-ligands.
Mayes K, Elsayed Z, Alhazmi A, Waters M, Alkhatib SG, Roberts M, Song C, Peterson K, Chan V, Ailaney N, Malapati P, Blevins T, Lisnić B, Dumur CI, Landry JW. Mayes K, et al. Among authors: elsayed z. Oncotarget. 2017 May 12;8(38):64344-64357. doi: 10.18632/oncotarget.17834. eCollection 2017 Sep 8. Oncotarget. 2017. PMID: 28969075 Free PMC article.
Therapeutic targeting Tudor domains in leukemia via CRISPR-Scan Assisted Drug Discovery.
Chan AKN, Han L, Delaney CD, Wang X, Mukhaleva E, Li M, Yang L, Pokharel SP, Mattson N, Garcia M, Wang B, Xu X, Zhang L, Singh P, Elsayed Z, Chen R, Kuang B, Wang J, Yuan YC, Chen B, Chan LN, Rosen ST, Horne D, Müschen M, Chen J, Vaidehi N, Armstrong SA, Su R, Chen CW. Chan AKN, et al. Among authors: elsayed z. Sci Adv. 2024 Feb 23;10(8):eadk3127. doi: 10.1126/sciadv.adk3127. Epub 2024 Feb 23. Sci Adv. 2024. PMID: 38394203 Free PMC article.
Inhibition of Proprotein Convertase Subtilisin/Kexin-9 After Kidney Transplant: Single-Center Experience Among Patients With High Cardiovascular Risk.
Alotaibi T, Nagib AM, Denewar A, Aboateya H, Halim MA, Mahmoud T, Abdelmonem M, El-Sayed Z, Mostafa M, Emam M, Alotaibi A, Nair P, Gheith O. Alotaibi T, et al. Exp Clin Transplant. 2024 Jan;22(Suppl 1):315-322. doi: 10.6002/ect.MESOT2023.P111. Exp Clin Transplant. 2024. PMID: 38385418 Free article. Clinical Trial.
A novel class of inhibitors that disrupts the stability of integrin heterodimers identified by CRISPR-tiling-instructed genetic screens.
Mattson NM, Chan AKN, Miyashita K, Mukhaleva E, Chang WH, Yang L, Ma N, Wang Y, Pokharel SP, Li M, Liu Q, Xu X, Chen R, Singh P, Zhang L, Elsayed Z, Chen B, Keen D, Pirrotte P, Rosen ST, Chen J, LaBarge MA, Shively JE, Vaidehi N, Rockne RC, Feng M, Chen CW. Mattson NM, et al. Among authors: elsayed z. Nat Struct Mol Biol. 2024 Mar;31(3):465-475. doi: 10.1038/s41594-024-01211-y. Epub 2024 Feb 5. Nat Struct Mol Biol. 2024. PMID: 38316881 Free PMC article.
Novel indolinone-tethered benzothiophenes as anti-tubercular agents against MDR/XDR M. tuberculosis: Design, synthesis, biological evaluation and in vivo pharmacokinetic study.
Eldehna WM, Mahmoud ST, Elshnawey ER, Elsayed ZM, Majrashi TA, El-Ashrey MK, Rashed M, Hemeda LR, Shoun AA, Elkaeed EB, El Hassab MA, Abdel-Aziz MM, Shahin MI. Eldehna WM, et al. Among authors: elsayed zm. Bioorg Chem. 2024 Feb;143:107009. doi: 10.1016/j.bioorg.2023.107009. Epub 2023 Nov 29. Bioorg Chem. 2024. PMID: 38070474
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