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Synthesis, characterization and antineoplastic activity of bis-aziridinyl dimeric naphthoquinone - A novel class of compounds with potent activity against acute myeloid leukemia cells.
Carter-Cooper BA, Fletcher S, Ferraris D, Choi EY, Kronfli D, Dash S, Truong P, Sausville EA, Lapidus RG, Emadi A. Carter-Cooper BA, et al. Among authors: emadi a. Bioorg Med Chem Lett. 2017 Jan 1;27(1):6-10. doi: 10.1016/j.bmcl.2016.11.045. Epub 2016 Nov 17. Bioorg Med Chem Lett. 2017. PMID: 27890379 Free PMC article.
Pre-Clinical Activity of Amino-Alcohol Dimeric Naphthoquinones as Potential Therapeutics for Acute Myeloid Leukemia.
Ferraris D, Lapidus R, Truong P, Bollino D, Carter-Cooper B, Lee M, Chang E, LaRossa-Garcia M, Dash S, Gartenhaus R, Choi EY, Kipe O, Lam V, Mason K, Palmer R, Williams E, Ambulos N, Kamangar F, Zhang Y, Kapadia B, Jing Y, Emadi A. Ferraris D, et al. Among authors: emadi a. Anticancer Agents Med Chem. 2022;22(2):239-253. doi: 10.2174/1871520621666210602131558. Anticancer Agents Med Chem. 2022. PMID: 34080968
Cyclophosphamide and cancer: golden anniversary.
Emadi A, Jones RJ, Brodsky RA. Emadi A, et al. Nat Rev Clin Oncol. 2009 Nov;6(11):638-47. doi: 10.1038/nrclinonc.2009.146. Epub 2009 Sep 29. Nat Rev Clin Oncol. 2009. PMID: 19786984 Review.
Ruthenium-based chemotherapeutics: are they ready for prime time?
Antonarakis ES, Emadi A. Antonarakis ES, et al. Among authors: emadi a. Cancer Chemother Pharmacol. 2010 May;66(1):1-9. doi: 10.1007/s00280-010-1293-1. Epub 2010 Mar 6. Cancer Chemother Pharmacol. 2010. PMID: 20213076 Free PMC article. Review.
Hydroxylated Dimeric Naphthoquinones Increase the Generation of Reactive Oxygen Species, Induce Apoptosis of Acute Myeloid Leukemia Cells and Are Not Substrates of the Multidrug Resistance Proteins ABCB1 and ABCG2.
Lapidus RG, Carter-Cooper BA, Sadowska M, Choi EY, Wonodi O, Muvarak N, Natarajan K, Pidugu LS, Jaiswal A, Toth EA, Rassool FV, Etemadi A, Sausville EA, Baer MR, Emadi A. Lapidus RG, et al. Among authors: emadi a. Pharmaceuticals (Basel). 2016 Jan 19;9(1):4. doi: 10.3390/ph9010004. Pharmaceuticals (Basel). 2016. PMID: 26797621 Free PMC article.
174 results