Emoto C - Search Results

1

Modeling and simulation in pediatric drug therapy: Application of pharmacometrics to define the right dose for children.

Vinks AA, Emoto C, Fukuda T. Vinks AA, et al. Among authors: emoto c. Clin Pharmacol Ther. 2015 Sep;98(3):298-308. doi: 10.1002/cpt.169. Epub 2015 Jul 20. Clin Pharmacol Ther. 2015. PMID: 26073179 Review.

2

The impact of CYP3A5*3 polymorphism on sirolimus pharmacokinetics: insights from predictions with a physiologically-based pharmacokinetic model.

Emoto C, Fukuda T, Venkatasubramanian R, Vinks AA. Emoto C, et al. Br J Clin Pharmacol. 2015 Dec;80(6):1438-46. doi: 10.1111/bcp.12743. Epub 2015 Oct 28. Br J Clin Pharmacol. 2015. PMID: 26256674 Free PMC article.

3

Model-based precision dosing of sirolimus in pediatric patients with vascular anomalies.

Mizuno T, Emoto C, Fukuda T, Hammill AM, Adams DM, Vinks AA. Mizuno T, et al. Among authors: emoto c. Eur J Pharm Sci. 2017 Nov 15;109S:S124-S131. doi: 10.1016/j.ejps.2017.05.037. Epub 2017 May 17. Eur J Pharm Sci. 2017. PMID: 28526601 Clinical Trial.

4

Influence of OCT1 Ontogeny and Genetic Variation on Morphine Disposition in Critically Ill Neonates: Lessons From PBPK Modeling and Clinical Study.

Hahn D, Emoto C, Euteneuer JC, Mizuno T, Vinks AA, Fukuda T. Hahn D, et al. Among authors: emoto c. Clin Pharmacol Ther. 2019 Mar;105(3):761-768. doi: 10.1002/cpt.1249. Epub 2018 Nov 8. Clin Pharmacol Ther. 2019. PMID: 30300922

5

Model-informed precision dosing for alemtuzumab in paediatric and young adult patients undergoing allogeneic haematopoietic cell transplantation.

Dong M, Emoto C, Fukuda T, Arnold DE, Mehta PA, Marsh RA, Vinks AA. Dong M, et al. Among authors: emoto c. Br J Clin Pharmacol. 2022 Jan;88(1):248-259. doi: 10.1111/bcp.14955. Epub 2021 Jul 18. Br J Clin Pharmacol. 2022. PMID: 34182590 Free article.

6

Next Challenge From the Variance in Individual Physiologically-Based Pharmacokinetic Model-Predicted to Observed Morphine Concentration in Critically Ill Neonates.

Emoto C, Hahn D, Euteneuer JC, Mizuno T, Vinks AA, Fukuda T. Emoto C, et al. Clin Pharmacol Ther. 2020 Feb;107(2):319-320. doi: 10.1002/cpt.1607. Epub 2019 Sep 12. Clin Pharmacol Ther. 2020. PMID: 31513716 Free PMC article. No abstract available.

7

Characterizing the Developmental Trajectory of Sirolimus Clearance in Neonates and Infants.

Emoto C, Fukuda T, Mizuno T, Schniedewind B, Christians U, Adams DM, Vinks AA. Emoto C, et al. CPT Pharmacometrics Syst Pharmacol. 2016 Aug;5(8):411-7. doi: 10.1002/psp4.12096. Epub 2016 Aug 8. CPT Pharmacometrics Syst Pharmacol. 2016. PMID: 27501453 Free PMC article. Clinical Trial.

8

Age-dependent changes in sirolimus metabolite formation in patients with neurofibromatosis type 1.

Emoto C, Fukuda T, Mizuno T, Cox S, Schniedewind B, Christians U, Widemann BC, Fisher MJ, Weiss B, Perentesis J, Vinks AA. Emoto C, et al. Ther Drug Monit. 2015 Jun;37(3):395-9. doi: 10.1097/FTD.0000000000000130. Ther Drug Monit. 2015. PMID: 25162215 Clinical Trial.

9

Risk Assessment of Drug-Drug Interactions of Calcineurin Inhibitors Affecting Sirolimus Pharmacokinetics in Renal Transplant Patients.

Emoto C, Vinks AA, Fukuda T. Emoto C, et al. Ther Drug Monit. 2016 Oct;38(5):607-13. doi: 10.1097/FTD.0000000000000314. Ther Drug Monit. 2016. PMID: 27310200

10

A Prospective Study of Alemtuzumab as a Second-Line Agent for Steroid-Refractory Acute Graft-versus-Host Disease in Pediatric and Young Adult Allogeneic Hematopoietic Stem Cell Transplantation.

Khandelwal P, Emoto C, Fukuda T, Vinks AA, Neumeier L, Dandoy CE, El-Bietar J, Chandra S, Davies SM, Bleesing JJ, Jordan MB, Mehta PA, Jodele S, Grimley MS, Kumar A, Myers KC, Marsh RA. Khandelwal P, et al. Among authors: emoto c. Biol Blood Marrow Transplant. 2016 Dec;22(12):2220-2225. doi: 10.1016/j.bbmt.2016.09.016. Epub 2016 Sep 21. Biol Blood Marrow Transplant. 2016. PMID: 27664325 Free PMC article.

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