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Promising effects of emoxypine and its succinate derivative in the management of various diseases-with insights on recent patent applications.
Gupta DS, Bagwe Parab S, Kaur G. Gupta DS, et al. Curr Res Pharmacol Drug Discov. 2022 Aug 1;3:100121. doi: 10.1016/j.crphar.2022.100121. eCollection 2022. Curr Res Pharmacol Drug Discov. 2022. PMID: 35992374 Free PMC article. Review.
Emoxypine and its succinate derivative share a common hydroxypridine structure, which is similar to pyridoxine. ...The primary focus of this review is to shed light on the broad spectrum of pharmacological properties offered by emoxypine and its succinate derivative …
Emoxypine and its succinate derivative share a common hydroxypridine structure, which is similar to pyridoxine. ...The primary focus …
Emoxypine succinate modulates behavioral and molecular responses in zebrafish model of iron Overload-Induced neuroinflammation via CDK5/GSK3- beta and NLRP3 inflammasome pathway.
Bagwe Parab S, Kaur G. Bagwe Parab S, et al. Brain Res. 2025 Jan 1;1846:149236. doi: 10.1016/j.brainres.2024.149236. Epub 2024 Sep 12. Brain Res. 2025. PMID: 39270994
Following induction, Emoxypine succinate was employed as a treatment intervention for 14 days (concentrations of 4 mg/L, 8 mg/L, and 12 mg/L). ...This comprehensive study highlights the potential efficacy of emoxypine succinate in mitigating neurodegeneration associ …
Following induction, Emoxypine succinate was employed as a treatment intervention for 14 days (concentrations of 4 mg/L, 8 mg/L, and …
Pharmaceutical salts of emoxypine with dicarboxylic acids.
Manin AN, Voronin AP, Drozd KV, Churakov AV, Perlovich GL. Manin AN, et al. Acta Crystallogr C Struct Chem. 2018 Jul 1;74(Pt 7):797-806. doi: 10.1107/S2053229618007386. Epub 2018 Jun 5. Acta Crystallogr C Struct Chem. 2018. PMID: 29973419
New salt forms of the antioxidant drug emoxypine (EMX, 2-ethyl-6-methylpyridin-3-ol) with pharmaceutically acceptable maleic (Mlt), malonic (Mln) and adipic (Adp) acids were obtained {emoxypinium maleate, C(8)H(12)NO(+).C(4)H(3)O(4)(-), [EMX+Mlt], emoxypinium malonate, C(8 …
New salt forms of the antioxidant drug emoxypine (EMX, 2-ethyl-6-methylpyridin-3-ol) with pharmaceutically acceptable maleic (Mlt), m …
Emoxypine as a Potential Marker for Identifying Possible Cases of Unintended Meldonium Doping in Sports.
Postnikov PV, Efimova YA, Rodin IA. Postnikov PV, et al. Drug Test Anal. 2026 Mar;18(3):414-418. doi: 10.1002/dta.70031. Epub 2026 Jan 29. Drug Test Anal. 2026. PMID: 41611212
The drug dissociates into two antihypoxants-meldonium, a metabolic modulator prohibited in sports, and emoxypine, which also has antioxidant properties. A small-scale pilot study involved three volunteers consuming a single 900-mL dose of unpasteurized cow's milk collected …
The drug dissociates into two antihypoxants-meldonium, a metabolic modulator prohibited in sports, and emoxypine, which also has anti …
Mexidol, Cytoflavin, and succinic acid derivatives as antihypoxic, anti-ischemic metabolic modulators, and ergogenic aids in athletes and consideration of their potential as performance enhancing drugs.
Jędrejko K, Catlin O, Stewart T, Muszyńska B. Jędrejko K, et al. Drug Test Anal. 2024 Dec;16(12):1436-1467. doi: 10.1002/dta.3655. Epub 2024 Feb 25. Drug Test Anal. 2024. PMID: 38403950 Review.
Emoxypine (ethylmethylhydroxypyridine) is a synthetic derivative of vitamin B(6). Emoxypine succinate is a registered drug in Russia and Ukraine under various trade names including Mexidol, Mexicor, and Armadin Long. ...Metabolic Modulators. The conjugation of em …
Emoxypine (ethylmethylhydroxypyridine) is a synthetic derivative of vitamin B(6). Emoxypine succinate is a registered drug in …
[Effect of magnesium, acetylsalicilic acid and emoxypine on aggregation of platelets].
Loznikova SZh, Sukhodola AA, Shcharbina NIu, Shcharbin DG. Loznikova SZh, et al. Biofizika. 2014 Nov-Dec;59(6):1108-12. Biofizika. 2014. PMID: 25715617 Russian.
The thrombin-induced platelet aggregation was studied in the absence and presence of magnesium sulfate, acetylsalicylic acid and emoxypine. It was found that all the preparations studied were able separately to decrease platelet aggregation. ...
The thrombin-induced platelet aggregation was studied in the absence and presence of magnesium sulfate, acetylsalicylic acid and emoxypin …
[The effect of the synthetic antioxidant emoxypine on the tonus of the coronary vessels].
Pashin EN, Shvedova AA. Pashin EN, et al. Farmakol Toksikol. 1989 Sep-Oct;52(5):17-9. Farmakol Toksikol. 1989. PMID: 2599070 Russian.
Emoxypine failed to change the structure of the phase coronary blood flow. When administered at the concentration of 5.10(-4)M emoxypine increased the volume rate of the perfusate outflow from the rat isolated heart cavities and decreased the value of potassium cont …
Emoxypine failed to change the structure of the phase coronary blood flow. When administered at the concentration of 5.10(-4)M emo …
[Efficacy of emoxypine in combined therapy for elderly patients with postinfarct cardiosclerosis and heart failure].
Zaslavskaia RM, Lilitsa GV, Kalinina EV. Zaslavskaia RM, et al. Klin Med (Mosk). 2004;82(12):19-21. Klin Med (Mosk). 2004. PMID: 15732713 Russian.
The results of the study suggest that emoxypine significantly improves the clinical symptomatology and shows marked antianginal and antiischemic effects. ...By taking into account the foregoing, it should be stated that it is expedient to include emoxypine into CT f …
The results of the study suggest that emoxypine significantly improves the clinical symptomatology and shows marked antianginal and a …
[Effect of mexidol, emoxypine, and dimephosphon on electrophysiological effects of nibentan].
Kotliarov AA, Kurkina NV, Smirnova LE, Balykova LA. Kotliarov AA, et al. Eksp Klin Farmakol. 2002 Mar-Apr;65(2):27-30. Eksp Klin Farmakol. 2002. PMID: 12109287 Russian.
Mexidol, emoxypine, and dimephosphon decrease the acute toxicity of nibentan in mice. In the experiments on cats, these drugs reduced the negative dromotropic action of nibentan and prevented an increase in the effective refractory period of the atrioventricular node and v …
Mexidol, emoxypine, and dimephosphon decrease the acute toxicity of nibentan in mice. In the experiments on cats, these drugs reduced …
[Effect of emoxypine on myocardial electrical instability and homeostasis parameters in patients with acute disturbance of cerebrovascular circulation].
Stoliarova VV. Stoliarova VV. Eksp Klin Farmakol. 2002 May-Jun;65(3):13-5. Eksp Klin Farmakol. 2002. PMID: 12227086 Clinical Trial. Russian.
The control group (30 patients) received standard complex therapy, while the test group (19 patients) additionally received emoxypine. The administration of emoxypine reduced the incidence of myocardial ischemia and positively influenced the QT interval variance and …
The control group (30 patients) received standard complex therapy, while the test group (19 patients) additionally received emoxypine …
479 results