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Promising effects of emoxypine and its succinate derivative in the management of various diseases-with insights on recent patent applications.
Gupta DS, Bagwe Parab S, Kaur G. Gupta DS, et al. Curr Res Pharmacol Drug Discov. 2022 Aug 1;3:100121. doi: 10.1016/j.crphar.2022.100121. eCollection 2022. Curr Res Pharmacol Drug Discov. 2022. PMID: 35992374 Free PMC article. Review.
Emoxypine and its succinate derivative share a common hydroxypridine structure, which is similar to pyridoxine. ...The primary focus of this review is to shed light on the broad spectrum of pharmacological properties offered by emoxypine and its succinate derivative …
Emoxypine and its succinate derivative share a common hydroxypridine structure, which is similar to pyridoxine. ...The primary focus …
Pharmaceutical salts of emoxypine with dicarboxylic acids.
Manin AN, Voronin AP, Drozd KV, Churakov AV, Perlovich GL. Manin AN, et al. Acta Crystallogr C Struct Chem. 2018 Jul 1;74(Pt 7):797-806. doi: 10.1107/S2053229618007386. Epub 2018 Jun 5. Acta Crystallogr C Struct Chem. 2018. PMID: 29973419
New salt forms of the antioxidant drug emoxypine (EMX, 2-ethyl-6-methylpyridin-3-ol) with pharmaceutically acceptable maleic (Mlt), malonic (Mln) and adipic (Adp) acids were obtained {emoxypinium maleate, C(8)H(12)NO(+).C(4)H(3)O(4)(-), [EMX+Mlt], emoxypinium malonate, C(8 …
New salt forms of the antioxidant drug emoxypine (EMX, 2-ethyl-6-methylpyridin-3-ol) with pharmaceutically acceptable maleic (Mlt), m …
Emoxypine succinate modulates behavioral and molecular responses in zebrafish model of iron Overload-Induced neuroinflammation via CDK5/GSK3- beta and NLRP3 inflammasome pathway.
Bagwe Parab S, Kaur G. Bagwe Parab S, et al. Brain Res. 2025 Jan 1;1846:149236. doi: 10.1016/j.brainres.2024.149236. Epub 2024 Sep 12. Brain Res. 2025. PMID: 39270994
Following induction, Emoxypine succinate was employed as a treatment intervention for 14 days (concentrations of 4 mg/L, 8 mg/L, and 12 mg/L). ...This comprehensive study highlights the potential efficacy of emoxypine succinate in mitigating neurodegeneration associ …
Following induction, Emoxypine succinate was employed as a treatment intervention for 14 days (concentrations of 4 mg/L, 8 mg/L, and …
[Effect of magnesium, acetylsalicilic acid and emoxypine on aggregation of platelets].
Loznikova SZh, Sukhodola AA, Shcharbina NIu, Shcharbin DG. Loznikova SZh, et al. Biofizika. 2014 Nov-Dec;59(6):1108-12. Biofizika. 2014. PMID: 25715617 Russian.
The thrombin-induced platelet aggregation was studied in the absence and presence of magnesium sulfate, acetylsalicylic acid and emoxypine. It was found that all the preparations studied were able separately to decrease platelet aggregation. ...
The thrombin-induced platelet aggregation was studied in the absence and presence of magnesium sulfate, acetylsalicylic acid and emoxypin …
Unauthorized ingredients in "nootropic" dietary supplements: A review of the history, pharmacology, prevalence, international regulations, and potential as doping agents.
Jędrejko K, Catlin O, Stewart T, Anderson A, Muszyńska B, Catlin DH. Jędrejko K, et al. Drug Test Anal. 2023 Aug;15(8):803-839. doi: 10.1002/dta.3529. Epub 2023 Jun 25. Drug Test Anal. 2023. PMID: 37357012 Review.
Many popular nootropics are unauthorized food or DS ingredients according to the European Commission including huperzine A, yohimbine, and dimethylaminoethanol; unapproved pharmaceuticals like phenibut or emoxypine (mexidol); previously registered drugs like meclofenoxate …
Many popular nootropics are unauthorized food or DS ingredients according to the European Commission including huperzine A, yohimbine, and d …
[Combined administration of mexidol with known medicines].
Voronina TA, Ivanova EA. Voronina TA, et al. Zh Nevrol Psikhiatr Im S S Korsakova. 2019;119(4):115-124. doi: 10.17116/jnevro2019119041115. Zh Nevrol Psikhiatr Im S S Korsakova. 2019. PMID: 31156232 Review. Russian.
Mexidol, Cytoflavin, and succinic acid derivatives as antihypoxic, anti-ischemic metabolic modulators, and ergogenic aids in athletes and consideration of their potential as performance enhancing drugs.
Jędrejko K, Catlin O, Stewart T, Muszyńska B. Jędrejko K, et al. Drug Test Anal. 2024 Dec;16(12):1436-1467. doi: 10.1002/dta.3655. Epub 2024 Feb 25. Drug Test Anal. 2024. PMID: 38403950 Review.
Emoxypine (ethylmethylhydroxypyridine) is a synthetic derivative of vitamin B(6). Emoxypine succinate is a registered drug in Russia and Ukraine under various trade names including Mexidol, Mexicor, and Armadin Long. ...Metabolic Modulators. The conjugation of em …
Emoxypine (ethylmethylhydroxypyridine) is a synthetic derivative of vitamin B(6). Emoxypine succinate is a registered drug in …
[An effect of 3-oxypyridine and succinic acid derivatives on the time of reduction of anxiety and depression symptoms in alcohol withdrawal treatment].
Volchegorskii IA, Izarovskii BV, Shamaeva TN, Izarovskaia IV. Volchegorskii IA, et al. Zh Nevrol Psikhiatr Im S S Korsakova. 2021;121(9):63-71. doi: 10.17116/jnevro202112109163. Zh Nevrol Psikhiatr Im S S Korsakova. 2021. PMID: 34693691 Clinical Trial. Russian.
OBJECTIVE: To compare the effect of 3-oxypyridine and succinic acid derivatives (emoxypine, reamberin, mexidol) on the time of reduction of anxiety and depression symptoms in the standard treatment of alcohol withdrawal syndrome (AWS). ...Emoxypine and reamberin red …
OBJECTIVE: To compare the effect of 3-oxypyridine and succinic acid derivatives (emoxypine, reamberin, mexidol) on the time of reduct …
[Efficacy of emoxypine in combined therapy for elderly patients with postinfarct cardiosclerosis and heart failure].
Zaslavskaia RM, Lilitsa GV, Kalinina EV. Zaslavskaia RM, et al. Klin Med (Mosk). 2004;82(12):19-21. Klin Med (Mosk). 2004. PMID: 15732713 Russian.
The results of the study suggest that emoxypine significantly improves the clinical symptomatology and shows marked antianginal and antiischemic effects. ...By taking into account the foregoing, it should be stated that it is expedient to include emoxypine into CT f …
The results of the study suggest that emoxypine significantly improves the clinical symptomatology and shows marked antianginal and a …
[The effect of the synthetic antioxidant emoxypine on the tonus of the coronary vessels].
Pashin EN, Shvedova AA. Pashin EN, et al. Farmakol Toksikol. 1989 Sep-Oct;52(5):17-9. Farmakol Toksikol. 1989. PMID: 2599070 Russian.
Emoxypine failed to change the structure of the phase coronary blood flow. When administered at the concentration of 5.10(-4)M emoxypine increased the volume rate of the perfusate outflow from the rat isolated heart cavities and decreased the value of potassium cont …
Emoxypine failed to change the structure of the phase coronary blood flow. When administered at the concentration of 5.10(-4)M emo …
462 results