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Genetically defined adult-type hypolactasia and self-reported lactose intolerance as risk factors of osteoporosis in Finnish postmenopausal women.
Enattah N, Pekkarinen T, Välimäki MJ, Löyttyniemi E, Järvelä I. Enattah N, et al. Eur J Clin Nutr. 2005 Oct;59(10):1105-11. doi: 10.1038/sj.ejcn.1602219. Eur J Clin Nutr. 2005. PMID: 16015262 Free article.
Correlation of intestinal disaccharidase activities with the C/T-13910 variant and age.
Enattah NS, Kuokkanen M, Forsblom C, Natah S, Oksanen A, Jarvela I, Peltonen L, Savilahti E. Enattah NS, et al. World J Gastroenterol. 2007 Jul 7;13(25):3508-12. doi: 10.3748/wjg.v13.i25.3508. World J Gastroenterol. 2007. PMID: 17659699 Free PMC article.
Genetic variant of lactase-persistent C/T-13910 is associated with bone fractures in very old age.
Enattah NS, Sulkava R, Halonen P, Kontula K, Järvelä I. Enattah NS, et al. J Am Geriatr Soc. 2005 Jan;53(1):79-82. doi: 10.1111/j.1532-5415.2005.53014.x. J Am Geriatr Soc. 2005. PMID: 15667380
Independent introduction of two lactase-persistence alleles into human populations reflects different history of adaptation to milk culture.
Enattah NS, Jensen TG, Nielsen M, Lewinski R, Kuokkanen M, Rasinpera H, El-Shanti H, Seo JK, Alifrangis M, Khalil IF, Natah A, Ali A, Natah S, Comas D, Mehdi SQ, Groop L, Vestergaard EM, Imtiaz F, Rashed MS, Meyer B, Troelsen J, Peltonen L. Enattah NS, et al. Am J Hum Genet. 2008 Jan;82(1):57-72. doi: 10.1016/j.ajhg.2007.09.012. Am J Hum Genet. 2008. PMID: 18179885 Free PMC article.
Evidence of still-ongoing convergence evolution of the lactase persistence T-13910 alleles in humans.
Enattah NS, Trudeau A, Pimenoff V, Maiuri L, Auricchio S, Greco L, Rossi M, Lentze M, Seo JK, Rahgozar S, Khalil I, Alifrangis M, Natah S, Groop L, Shaat N, Kozlov A, Verschubskaya G, Comas D, Bulayeva K, Mehdi SQ, Terwilliger JD, Sahi T, Savilahti E, Perola M, Sajantila A, Järvelä I, Peltonen L. Enattah NS, et al. Am J Hum Genet. 2007 Sep;81(3):615-25. doi: 10.1086/520705. Epub 2007 Aug 7. Am J Hum Genet. 2007. PMID: 17701907 Free PMC article.
Identification of a variant associated with adult-type hypolactasia.
Enattah NS, Sahi T, Savilahti E, Terwilliger JD, Peltonen L, Järvelä I. Enattah NS, et al. Nat Genet. 2002 Feb;30(2):233-7. doi: 10.1038/ng826. Epub 2002 Jan 14. Nat Genet. 2002. PMID: 11788828
Mutations in the translated region of the lactase gene (LCT) underlie congenital lactase deficiency.
Kuokkanen M, Kokkonen J, Enattah NS, Ylisaukko-Oja T, Komu H, Varilo T, Peltonen L, Savilahti E, Jarvela I. Kuokkanen M, et al. Among authors: enattah ns. Am J Hum Genet. 2006 Feb;78(2):339-44. doi: 10.1086/500053. Epub 2005 Dec 15. Am J Hum Genet. 2006. PMID: 16400612 Free PMC article.
Molecularly defined lactose malabsorption, peak bone mass and bone turnover rate in young finnish men.
Enattah N, Välimäki VV, Välimäki MJ, Löyttyniemi E, Sahi T, Järvelä I. Enattah N, et al. Calcif Tissue Int. 2004 Dec;75(6):488-93. doi: 10.1007/s00223-004-0029-9. Epub 2004 Sep 16. Calcif Tissue Int. 2004. PMID: 15365657
The C/C-13910 genotype of adult-type hypolactasia is associated with an increased risk of colorectal cancer in the Finnish population.
Rasinperä H, Forsblom C, Enattah NS, Halonen P, Salo K, Victorzon M, Mecklin JP, Järvinen H, Enholm S, Sellick G, Alazzouzi H, Houlston R, Robinson J, Groop PH, Tomlinson I, Schwartz S Jr, Aaltonen LA, Järvelä I; FinnDiane Study Group. Rasinperä H, et al. Among authors: enattah ns. Gut. 2005 May;54(5):643-7. doi: 10.1136/gut.2004.055939. Gut. 2005. PMID: 15831909 Free PMC article.
A genetic test which can be used to diagnose adult-type hypolactasia in children.
Rasinperä H, Savilahti E, Enattah NS, Kuokkanen M, Tötterman N, Lindahl H, Järvelä I, Kolho KL. Rasinperä H, et al. Among authors: enattah ns. Gut. 2004 Nov;53(11):1571-6. doi: 10.1136/gut.2004.040048. Gut. 2004. PMID: 15479673 Free PMC article.
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