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Targeting protein aggregation for the treatment of degenerative diseases.
Eisele YS, Monteiro C, Fearns C, Encalada SE, Wiseman RL, Powers ET, Kelly JW. Eisele YS, et al. Among authors: encalada se. Nat Rev Drug Discov. 2015 Nov;14(11):759-80. doi: 10.1038/nrd4593. Epub 2015 Sep 4. Nat Rev Drug Discov. 2015. PMID: 26338154 Free PMC article. Review.
A fluorogenic aryl fluorosulfate for intraorganellar transthyretin imaging in living cells and in Caenorhabditis elegans.
Baranczak A, Liu Y, Connelly S, Du WG, Greiner ER, Genereux JC, Wiseman RL, Eisele YS, Bradbury NC, Dong J, Noodleman L, Sharpless KB, Wilson IA, Encalada SE, Kelly JW. Baranczak A, et al. Among authors: encalada se. J Am Chem Soc. 2015 Jun 17;137(23):7404-14. doi: 10.1021/jacs.5b03042. Epub 2015 Jun 8. J Am Chem Soc. 2015. PMID: 26051248 Free PMC article.
Cellular clearance of circulating transthyretin decreases cell-nonautonomous proteotoxicity in Caenorhabditis elegans.
Madhivanan K, Greiner ER, Alves-Ferreira M, Soriano-Castell D, Rouzbeh N, Aguirre CA, Paulsson JF, Chapman J, Jiang X, Ooi FK, Lemos C, Dillin A, Prahlad V, Kelly JW, Encalada SE. Madhivanan K, et al. Among authors: encalada se. Proc Natl Acad Sci U S A. 2018 Aug 14;115(33):E7710-E7719. doi: 10.1073/pnas.1801117115. Epub 2018 Jul 30. Proc Natl Acad Sci U S A. 2018. PMID: 30061394 Free PMC article.
Tau/MAPT disease-associated variant A152T alters tau function and toxicity via impaired retrograde axonal transport.
Butler VJ, Salazar DA, Soriano-Castell D, Alves-Ferreira M, Dennissen FJA, Vohra M, Oses-Prieto JA, Li KH, Wang AL, Jing B, Li B, Groisman A, Gutierrez E, Mooney S, Burlingame AL, Ashrafi K, Mandelkow EM, Encalada SE, Kao AW. Butler VJ, et al. Among authors: encalada se. Hum Mol Genet. 2019 May 1;28(9):1498-1514. doi: 10.1093/hmg/ddy442. Hum Mol Genet. 2019. PMID: 30590647 Free PMC article.
Endosomal sorting drives the formation of axonal prion protein endoggresomes.
Chassefeyre R, Chaiamarit T, Verhelle A, Novak SW, Andrade LR, Leitão ADG, Manor U, Encalada SE. Chassefeyre R, et al. Among authors: encalada se. Sci Adv. 2021 Dec 24;7(52):eabg3693. doi: 10.1126/sciadv.abg3693. Epub 2021 Dec 22. Sci Adv. 2021. PMID: 34936461 Free PMC article.
24 results