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Glycolipid-peptide vaccination induces liver-resident memory CD8+ T cells that protect against rodent malaria.
Holz LE, Chua YC, de Menezes MN, Anderson RJ, Draper SL, Compton BJ, Chan STS, Mathew J, Li J, Kedzierski L, Wang Z, Beattie L, Enders MH, Ghilas S, May R, Steiner TM, Lange J, Fernandez-Ruiz D, Valencia-Hernandez AM, Osmond TL, Farrand KJ, Seneviratna R, Almeida CF, Tullett KM, Bertolino P, Bowen DG, Cozijnsen A, Mollard V, McFadden GI, Caminschi I, Lahoud MH, Kedzierska K, Turner SJ, Godfrey DI, Hermans IF, Painter GF, Heath WR. Holz LE, et al. Among authors: enders mh. Sci Immunol. 2020 Jun 26;5(48):eaaz8035. doi: 10.1126/sciimmunol.aaz8035. Sci Immunol. 2020. PMID: 32591409
Development of a Novel CD4+ TCR Transgenic Line That Reveals a Dominant Role for CD8+ Dendritic Cells and CD40 Signaling in the Generation of Helper and CTL Responses to Blood-Stage Malaria.
Fernandez-Ruiz D, Lau LS, Ghazanfari N, Jones CM, Ng WY, Davey GM, Berthold D, Holz L, Kato Y, Enders MH, Bayarsaikhan G, Hendriks SH, Lansink LIM, Engel JA, Soon MSF, James KR, Cozijnsen A, Mollard V, Uboldi AD, Tonkin CJ, de Koning-Ward TF, Gilson PR, Kaisho T, Haque A, Crabb BS, Carbone FR, McFadden GI, Heath WR. Fernandez-Ruiz D, et al. Among authors: enders mh. J Immunol. 2017 Dec 15;199(12):4165-4179. doi: 10.4049/jimmunol.1700186. Epub 2017 Oct 30. J Immunol. 2017. PMID: 29084838 Free PMC article.
Resident Memory T Cells and Their Role within the Liver.
Ghilas S, Valencia-Hernandez AM, Enders MH, Heath WR, Fernandez-Ruiz D. Ghilas S, et al. Among authors: enders mh. Int J Mol Sci. 2020 Nov 13;21(22):8565. doi: 10.3390/ijms21228565. Int J Mol Sci. 2020. PMID: 33202970 Free PMC article. Review.
Plasmodium berghei Hsp90 contains a natural immunogenic I-Ab-restricted antigen common to rodent and human Plasmodium species.
Enders MH, Bayarsaikhan G, Ghilas S, Chua YC, May R, de Menezes MN, Ge Z, Tan PS, Cozijnsen A, Mollard V, Yui K, McFadden GI, Lahoud MH, Caminschi I, Purcell AW, Schittenhelm RB, Beattie L, Heath WR, Fernandez-Ruiz D. Enders MH, et al. Curr Res Immunol. 2021 Jun 30;2:79-92. doi: 10.1016/j.crimmu.2021.06.002. eCollection 2021. Curr Res Immunol. 2021. PMID: 35492393 Free PMC article.
A Natural Peptide Antigen within the Plasmodium Ribosomal Protein RPL6 Confers Liver TRM Cell-Mediated Immunity against Malaria in Mice.
Valencia-Hernandez AM, Ng WY, Ghazanfari N, Ghilas S, de Menezes MN, Holz LE, Huang C, English K, Naung M, Tan PS, Tullett KM, Steiner TM, Enders MH, Beattie L, Chua YC, Jones CM, Cozijnsen A, Mollard V, Cai Y, Bowen DG, Purcell AW, La Gruta NL, Villadangos JA, de Koning-Ward T, Barry AE, Barchet W, Cockburn IA, McFadden GI, Gras S, Lahoud MH, Bertolino P, Schittenhelm RB, Caminschi I, Heath WR, Fernandez-Ruiz D. Valencia-Hernandez AM, et al. Among authors: enders mh. Cell Host Microbe. 2020 Jun 10;27(6):950-962.e7. doi: 10.1016/j.chom.2020.04.010. Epub 2020 May 11. Cell Host Microbe. 2020. PMID: 32396839 Free article.
Ptpn2 and KLRG1 regulate the generation and function of tissue-resident memory CD8+ T cells in skin.
Hochheiser K, Wiede F, Wagner T, Freestone D, Enders MH, Olshansky M, Russ B, Nüssing S, Bawden E, Braun A, Bachem A, Gressier E, McConville R, Park SL, Jones CM, Davey GM, Gyorki DE, Tscharke D, Parish IA, Turner S, Herold MJ, Tiganis T, Bedoui S, Gebhardt T. Hochheiser K, et al. Among authors: enders mh. J Exp Med. 2021 Jun 7;218(6):e20200940. doi: 10.1084/jem.20200940. J Exp Med. 2021. PMID: 33914023 Free PMC article.