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A versatile cis-acting inverter module for synthetic translational switches.
Endo K, Hayashi K, Inoue T, Saito H. Endo K, et al. Nat Commun. 2013;4:2393. doi: 10.1038/ncomms3393. Nat Commun. 2013. PMID: 23999119 Free PMC article.
Synthetic RNA-protein complex shaped like an equilateral triangle.
Ohno H, Kobayashi T, Kabata R, Endo K, Iwasa T, Yoshimura SH, Takeyasu K, Inoue T, Saito H. Ohno H, et al. Nat Nanotechnol. 2011 Feb;6(2):116-20. doi: 10.1038/nnano.2010.268. Epub 2011 Jan 16. Nat Nanotechnol. 2011. PMID: 21240283
The construction of the complex relies on the proteins binding to kink-turn (K-turn) motifs in the RNA, which allows the RNA to bend by ∼ 60° at three positions to form a triangle. ...
The construction of the complex relies on the proteins binding to kink-turn (K-turn) motifs in the RNA, which allows the RNA to bend …
Feedback control of protein expression in mammalian cells by tunable synthetic translational inhibition.
Stapleton JA, Endo K, Fujita Y, Hayashi K, Takinoue M, Saito H, Inoue T. Stapleton JA, et al. ACS Synth Biol. 2012 Mar 16;1(3):83-8. doi: 10.1021/sb200005w. Epub 2011 Dec 6. ACS Synth Biol. 2012. PMID: 23651072 Free PMC article.
Quantitative and simultaneous translational control of distinct mammalian mRNAs.
Endo K, Stapleton JA, Hayashi K, Saito H, Inoue T. Endo K, et al. Nucleic Acids Res. 2013 Jul;41(13):e135. doi: 10.1093/nar/gkt347. Epub 2013 May 18. Nucleic Acids Res. 2013. PMID: 23685611 Free PMC article.
Engineering protein-responsive mRNA switch in mammalian cells.
Endo K, Saito H. Endo K, et al. Methods Mol Biol. 2014;1111:183-96. doi: 10.1007/978-1-62703-755-6_13. Methods Mol Biol. 2014. PMID: 24549620
Expanding the synthetic ribonucleoprotein world in cells.
Endo K, Parr C, Saito H. Endo K, et al. Nat Methods. 2014 Nov;11(11):1105-6. doi: 10.1038/nmeth.3148. Nat Methods. 2014. PMID: 25357239 No abstract available.
Efficient Detection and Purification of Cell Populations Using Synthetic MicroRNA Switches.
Miki K, Endo K, Takahashi S, Funakoshi S, Takei I, Katayama S, Toyoda T, Kotaka M, Takaki T, Umeda M, Okubo C, Nishikawa M, Oishi A, Narita M, Miyashita I, Asano K, Hayashi K, Osafune K, Yamanaka S, Saito H, Yoshida Y. Miki K, et al. Cell Stem Cell. 2015 Jun 4;16(6):699-711. doi: 10.1016/j.stem.2015.04.005. Epub 2015 May 21. Cell Stem Cell. 2015. PMID: 26004781
Mammalian synthetic circuits with RNA binding proteins for RNA-only delivery.
Wroblewska L, Kitada T, Endo K, Siciliano V, Stillo B, Saito H, Weiss R. Wroblewska L, et al. Nat Biotechnol. 2015 Aug;33(8):839-41. doi: 10.1038/nbt.3301. Epub 2015 Aug 3. Nat Biotechnol. 2015. PMID: 26237515 Free PMC article.
Numerical operations in living cells by programmable RNA devices.
Endo K, Hayashi K, Saito H. Endo K, et al. Sci Adv. 2019 Aug 21;5(8):eaax0835. doi: 10.1126/sciadv.aax0835. eCollection 2019 Aug. Sci Adv. 2019. PMID: 31457099 Free PMC article.
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