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Calcium lignosulphonate: re-evaluation of relevant endpoints to re-confirm validity and NOAEL of a 90-day feeding study in rats.
Thiel A, Braun W, Cary MG, Engelhardt JA, Goodman DG, Hall WC, Romeike A, Ward JM. Thiel A, et al. Regul Toxicol Pharmacol. 2013 Aug;66(3):286-99. doi: 10.1016/j.yrtph.2013.04.007. Epub 2013 May 7. Regul Toxicol Pharmacol. 2013. PMID: 23665266
Skeletal changes in rats given daily subcutaneous injections of recombinant human parathyroid hormone (1-34) for 2 years and relevance to human safety.
Vahle JL, Sato M, Long GG, Young JK, Francis PC, Engelhardt JA, Westmore MS, Linda Y, Nold JB. Vahle JL, et al. Toxicol Pathol. 2002 May-Jun;30(3):312-21. doi: 10.1080/01926230252929882. Toxicol Pathol. 2002. PMID: 12051548
Subchronic toxicity, metabolism, and pharmacokinetics of the aminobenzamide anticonvulsant ameltolide (LY201116) in rhesus monkeys.
Engelhardt JA, Parli CJ, Kovach PM, Shoufler JR, Emmerson JL, Leander JD. Engelhardt JA, et al. Fundam Appl Toxicol. 1992 Aug;19(2):197-201. doi: 10.1016/0272-0590(92)90151-7. Fundam Appl Toxicol. 1992. PMID: 1516775
Rubratoxin B mycotoxicosis in the Syrian hamster: ultrastructural alterations.
Engelhardt JA, Carlton WW, Hinsman EJ, Hayes AW. Engelhardt JA, et al. Exp Mol Pathol. 1989 Apr;50(2):193-204. doi: 10.1016/0014-4800(89)90030-0. Exp Mol Pathol. 1989. PMID: 2707382
Scientific and Regulatory Policy Committee Points-to-consider Paper*: Drug-induced Vascular Injury Associated with Nonsmall Molecule Therapeutics in Preclinical Development: Part I. Biotherapeutics.
Frazier KS, Engelhardt JA, Fant P, Guionaud S, Henry SP, Leach MW, Louden C, Scicchitano MS, Weaver JL, Zabka TS; Society of Toxicologic Pathology Vascular Injury Working Group. Frazier KS, et al. Among authors: engelhardt ja. Toxicol Pathol. 2015 Oct;43(7):915-34. doi: 10.1177/0192623315570340. Epub 2015 Feb 26. Toxicol Pathol. 2015. PMID: 25722122 Review.
Scientific and Regulatory Policy Committee Points-to-consider Paper*: Drug-induced Vascular Injury Associated with Nonsmall Molecule Therapeutics in Preclinical Development: Part 2. Antisense Oligonucleotides.
Engelhardt JA, Fant P, Guionaud S, Henry SP, Leach MW, Louden C, Scicchitano MS, Weaver JL, Zabka TS, Frazier KS; Society of Toxicologic Pathology Vascular Injury Working Group. Engelhardt JA, et al. Toxicol Pathol. 2015 Oct;43(7):935-44. doi: 10.1177/0192623315570341. Epub 2015 Feb 24. Toxicol Pathol. 2015. PMID: 25717082 Review.
Nonlesions, misdiagnoses, missed diagnoses, and other interpretive challenges in fish histopathology studies: a guide for investigators, authors, reviewers, and readers.
Wolf JC, Baumgartner WA, Blazer VS, Camus AC, Engelhardt JA, Fournie JW, Frasca S Jr, Groman DB, Kent ML, Khoo LH, Law JM, Lombardini ED, Ruehl-Fehlert C, Segner HE, Smith SA, Spitsbergen JM, Weber K, Wolfe MJ. Wolf JC, et al. Toxicol Pathol. 2015 Apr;43(3):297-325. doi: 10.1177/0192623314540229. Epub 2014 Aug 11. Toxicol Pathol. 2015. PMID: 25112278 Review.
Six-month continuous intraputamenal infusion toxicity study of recombinant methionyl human glial cell line-derived neurotrophic factor (r-metHuGDNF) in rhesus monkeys.
Hovland DN Jr, Boyd RB, Butt MT, Engelhardt JA, Moxness MS, Ma MH, Emery MG, Ernst NB, Reed RP, Zeller JR, Gash DM, Masterman DM, Potter BM, Cosenza ME, Lightfoot RM. Hovland DN Jr, et al. Toxicol Pathol. 2007 Aug;35(5):676-92. doi: 10.1080/01926230701481899. Toxicol Pathol. 2007. PMID: 17763282
Six-month continuous intraputamenal infusion toxicity study of recombinant methionyl human glial cell line-derived neurotrophic factor (r-metHuGDNF in rhesus monkeys.
Hovland DN Jr, Boyd RB, Butt MT, Engelhardt JA, Moxness MS, Ma MH, Emery MG, Ernst NB, Reed RP, Zeller JR, Gash DM, Masterman DM, Potter BM, Cosenza ME, Lightfoot RM. Hovland DN Jr, et al. Toxicol Pathol. 2007 Dec;35(7):1013-29. doi: 10.1177/01926230701481899. Toxicol Pathol. 2007. PMID: 18098052
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