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A catalytic domain variant of mitofusin requiring a wildtype paralog for function uncouples mitochondrial outer-membrane tethering and fusion.
Engelhart EA, Hoppins S. Engelhart EA, et al. J Biol Chem. 2019 May 17;294(20):8001-8014. doi: 10.1074/jbc.RA118.006347. Epub 2019 Apr 1. J Biol Chem. 2019. PMID: 30936207 Free PMC article.
Identification of a mitofusin specificity region that confers unique activities to Mfn1 and Mfn2.
Sloat SR, Whitley BN, Engelhart EA, Hoppins S. Sloat SR, et al. Among authors: engelhart ea. Mol Biol Cell. 2019 Aug 1;30(17):2309-2319. doi: 10.1091/mbc.E19-05-0291. Epub 2019 Jun 12. Mol Biol Cell. 2019. PMID: 31188717 Free PMC article.
Mitochondrial dynamics and their potential as a therapeutic target.
Whitley BN, Engelhart EA, Hoppins S. Whitley BN, et al. Among authors: engelhart ea. Mitochondrion. 2019 Nov;49:269-283. doi: 10.1016/j.mito.2019.06.002. Epub 2019 Jun 19. Mitochondrion. 2019. PMID: 31228566 Review.
Defective nucleotide-dependent assembly and membrane fusion in Mfn2 CMT2A variants improved by Bax.
Samanas NB, Engelhart EA, Hoppins S. Samanas NB, et al. Among authors: engelhart ea. Life Sci Alliance. 2020 Apr 3;3(5):e201900527. doi: 10.26508/lsa.201900527. Print 2020 May. Life Sci Alliance. 2020. PMID: 32245838 Free PMC article.
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