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Stress-induced β cell early senescence confers protection against type 1 diabetes.
Lee H, Sahin GS, Chen CW, Sonthalia S, Cañas SM, Oktay HZ, Duckworth AT, Brawerman G, Thompson PJ, Hatzoglou M, Eizirik DL, Engin F. Lee H, et al. Among authors: engin f. Cell Metab. 2023 Dec 5;35(12):2200-2215.e9. doi: 10.1016/j.cmet.2023.10.014. Epub 2023 Nov 9. Cell Metab. 2023. PMID: 37949065 Free article.
Adaptation to chronic ER stress enforces pancreatic β-cell plasticity.
Chen CW, Guan BJ, Alzahrani MR, Gao Z, Gao L, Bracey S, Wu J, Mbow CA, Jobava R, Haataja L, Zalavadia AH, Schaffer AE, Lee H, LaFramboise T, Bederman I, Arvan P, Mathews CE, Gerling IC, Kaestner KH, Tirosh B, Engin F, Hatzoglou M. Chen CW, et al. Among authors: engin f. Nat Commun. 2022 Aug 8;13(1):4621. doi: 10.1038/s41467-022-32425-7. Nat Commun. 2022. PMID: 35941159 Free PMC article.
Analysis of Half a Billion Datapoints Across Ten Machine-Learning Algorithms Identifies Key Elements Associated With Insulin Transcription in Human Pancreatic Islet Cells.
Wong WKM, Thorat V, Joglekar MV, Dong CX, Lee H, Chew YV, Bhave A, Hawthorne WJ, Engin F, Pant A, Dalgaard LT, Bapat S, Hardikar AA. Wong WKM, et al. Among authors: engin f. Front Endocrinol (Lausanne). 2022 Mar 23;13:853863. doi: 10.3389/fendo.2022.853863. eCollection 2022. Front Endocrinol (Lausanne). 2022. PMID: 35399953 Free PMC article.
31 results