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19 results
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Restoring endoplasmic reticulum function by chemical chaperones: an emerging therapeutic approach for metabolic diseases.
Engin F, Hotamisligil GS. Engin F, et al. Diabetes Obes Metab. 2010 Oct;12 Suppl 2:108-15. doi: 10.1111/j.1463-1326.2010.01282.x. Diabetes Obes Metab. 2010. PMID: 21029307 Review.
Cytokines induce endoplasmic reticulum stress in human, rat and mouse beta cells via different mechanisms.
Brozzi F, Nardelli TR, Lopes M, Millard I, Barthson J, Igoillo-Esteve M, Grieco FA, Villate O, Oliveira JM, Casimir M, Bugliani M, Engin F, Hotamisligil GS, Marchetti P, Eizirik DL. Brozzi F, et al. Among authors: engin f. Diabetologia. 2015 Oct;58(10):2307-16. doi: 10.1007/s00125-015-3669-6. Epub 2015 Jun 23. Diabetologia. 2015. PMID: 26099855
Restoration of the unfolded protein response in pancreatic β cells protects mice against type 1 diabetes.
Engin F, Yermalovich A, Nguyen T, Hummasti S, Fu W, Eizirik DL, Mathis D, Hotamisligil GS. Engin F, et al. Sci Transl Med. 2013 Nov 13;5(211):211ra156. doi: 10.1126/scitranslmed.3006534. Sci Transl Med. 2013. PMID: 24225943 Free PMC article.
Aberrant islet unfolded protein response in type 2 diabetes.
Engin F, Nguyen T, Yermalovich A, Hotamisligil GS. Engin F, et al. Sci Rep. 2014 Feb 11;4:4054. doi: 10.1038/srep04054. Sci Rep. 2014. PMID: 24514745 Free PMC article.
ER stress and development of type 1 diabetes.
Engin F. Engin F. J Investig Med. 2016 Jan;64(1):2-6. doi: 10.1097/JIM.0000000000000229. J Investig Med. 2016. PMID: 26230493 Free PMC article. Review.
Uncoupling of Metabolic Health from Longevity through Genetic Alteration of Adipose Tissue Lipid-Binding Proteins.
Charles KN, Li MD, Engin F, Arruda AP, Inouye K, Hotamisligil GS. Charles KN, et al. Among authors: engin f. Cell Rep. 2017 Oct 10;21(2):393-402. doi: 10.1016/j.celrep.2017.09.051. Cell Rep. 2017. PMID: 29020626 Free PMC article.
Notch signaling contributes to the pathogenesis of human osteosarcomas.
Engin F, Bertin T, Ma O, Jiang MM, Wang L, Sutton RE, Donehower LA, Lee B. Engin F, et al. Hum Mol Genet. 2009 Apr 15;18(8):1464-70. doi: 10.1093/hmg/ddp057. Epub 2009 Feb 19. Hum Mol Genet. 2009. PMID: 19228774 Free PMC article.
E-selectin ligand-1 regulates growth plate homeostasis in mice by inhibiting the intracellular processing and secretion of mature TGF-beta.
Yang T, Mendoza-Londono R, Lu H, Tao J, Li K, Keller B, Jiang MM, Shah R, Chen Y, Bertin TK, Engin F, Dabovic B, Rifkin DB, Hicks J, Jamrich M, Beaudet AL, Lee B. Yang T, et al. Among authors: engin f. J Clin Invest. 2010 Jul;120(7):2474-85. doi: 10.1172/JCI42150. Epub 2010 Jun 7. J Clin Invest. 2010. PMID: 20530870 Free PMC article.
NOTCHing the bone: insights into multi-functionality.
Engin F, Lee B. Engin F, et al. Bone. 2010 Feb;46(2):274-80. doi: 10.1016/j.bone.2009.05.027. Epub 2009 Jun 8. Bone. 2010. PMID: 19520195 Free PMC article. Review.
The Inhibitory G Protein α-Subunit, Gαz, Promotes Type 1 Diabetes-Like Pathophysiology in NOD Mice.
Fenske RJ, Cadena MT, Harenda QE, Wienkes HN, Carbajal K, Schaid MD, Laundre E, Brill AL, Truchan NA, Brar H, Wisinski J, Cai J, Graham TE, Engin F, Kimple ME. Fenske RJ, et al. Among authors: engin f. Endocrinology. 2017 Jun 1;158(6):1645-1658. doi: 10.1210/en.2016-1700. Endocrinology. 2017. PMID: 28419211 Free PMC article.
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