Engin F - Search Results

1

Aberrant islet unfolded protein response in type 2 diabetes.

Engin F, Nguyen T, Yermalovich A, Hotamisligil GS. Engin F, et al. Sci Rep. 2014 Feb 11;4:4054. doi: 10.1038/srep04054. Sci Rep. 2014. PMID: 24514745 Free PMC article.

2

Restoring endoplasmic reticulum function by chemical chaperones: an emerging therapeutic approach for metabolic diseases.

Engin F, Hotamisligil GS. Engin F, et al. Diabetes Obes Metab. 2010 Oct;12 Suppl 2:108-15. doi: 10.1111/j.1463-1326.2010.01282.x. Diabetes Obes Metab. 2010. PMID: 21029307 Review.

3

Restoration of the unfolded protein response in pancreatic β cells protects mice against type 1 diabetes.

Engin F, Yermalovich A, Nguyen T, Hummasti S, Fu W, Eizirik DL, Mathis D, Hotamisligil GS. Engin F, et al. Sci Transl Med. 2013 Nov 13;5(211):211ra156. doi: 10.1126/scitranslmed.3006534. Sci Transl Med. 2013. PMID: 24225943 Free PMC article.

4

Cytokines induce endoplasmic reticulum stress in human, rat and mouse beta cells via different mechanisms.

Brozzi F, Nardelli TR, Lopes M, Millard I, Barthson J, Igoillo-Esteve M, Grieco FA, Villate O, Oliveira JM, Casimir M, Bugliani M, Engin F, Hotamisligil GS, Marchetti P, Eizirik DL. Brozzi F, et al. Among authors: engin f. Diabetologia. 2015 Oct;58(10):2307-16. doi: 10.1007/s00125-015-3669-6. Epub 2015 Jun 23. Diabetologia. 2015. PMID: 26099855

5

Uncoupling of Metabolic Health from Longevity through Genetic Alteration of Adipose Tissue Lipid-Binding Proteins.

Charles KN, Li MD, Engin F, Arruda AP, Inouye K, Hotamisligil GS. Charles KN, et al. Among authors: engin f. Cell Rep. 2017 Oct 10;21(2):393-402. doi: 10.1016/j.celrep.2017.09.051. Cell Rep. 2017. PMID: 29020626 Free PMC article.

6

A hormone complex of FABP4 and nucleoside kinases regulates islet function.

Prentice KJ, Saksi J, Robertson LT, Lee GY, Inouye KE, Eguchi K, Lee A, Cakici O, Otterbeck E, Cedillo P, Achenbach P, Ziegler AG, Calay ES, Engin F, Hotamisligil GS. Prentice KJ, et al. Among authors: engin f. Nature. 2021 Dec;600(7890):720-726. doi: 10.1038/s41586-021-04137-3. Epub 2021 Dec 8. Nature. 2021. PMID: 34880500 Free PMC article.

7

ER stress and development of type 1 diabetes.

Engin F. Engin F. J Investig Med. 2016 Jan;64(1):2-6. doi: 10.1097/JIM.0000000000000229. J Investig Med. 2016. PMID: 26230493 Free PMC article. Review.

8

An accomplice more than a mere victim: The impact of β-cell ER stress on type 1 diabetes pathogenesis.

Sahin GS, Lee H, Engin F. Sahin GS, et al. Among authors: engin f. Mol Metab. 2021 Dec;54:101365. doi: 10.1016/j.molmet.2021.101365. Epub 2021 Oct 30. Mol Metab. 2021. PMID: 34728341 Free PMC article. Review.

9

The Inhibitory G Protein α-Subunit, Gαz, Promotes Type 1 Diabetes-Like Pathophysiology in NOD Mice.

Fenske RJ, Cadena MT, Harenda QE, Wienkes HN, Carbajal K, Schaid MD, Laundre E, Brill AL, Truchan NA, Brar H, Wisinski J, Cai J, Graham TE, Engin F, Kimple ME. Fenske RJ, et al. Among authors: engin f. Endocrinology. 2017 Jun 1;158(6):1645-1658. doi: 10.1210/en.2016-1700. Endocrinology. 2017. PMID: 28419211 Free PMC article.

10

Beta Cell Dedifferentiation Induced by IRE1α Deletion Prevents Type 1 Diabetes.

Lee H, Lee YS, Harenda Q, Pietrzak S, Oktay HZ, Schreiber S, Liao Y, Sonthalia S, Ciecko AE, Chen YG, Keles S, Sridharan R, Engin F. Lee H, et al. Among authors: engin f. Cell Metab. 2020 Apr 7;31(4):822-836.e5. doi: 10.1016/j.cmet.2020.03.002. Epub 2020 Mar 26. Cell Metab. 2020. PMID: 32220307 Free PMC article.

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