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Identification of cell types in multiplexed in situ images by combining protein expression and spatial information using CELESTA.
Zhang W, Li I, Reticker-Flynn NE, Good Z, Chang S, Samusik N, Saumyaa S, Li Y, Zhou X, Liang R, Kong CS, Le QT, Gentles AJ, Sunwoo JB, Nolan GP, Engleman EG, Plevritis SK. Zhang W, et al. Among authors: engleman eg. Nat Methods. 2022 Jun;19(6):759-769. doi: 10.1038/s41592-022-01498-z. Epub 2022 Jun 2. Nat Methods. 2022. PMID: 35654951 Free PMC article.
IMMUNOLOGY. An interactive reference framework for modeling a dynamic immune system.
Spitzer MH, Gherardini PF, Fragiadakis GK, Bhattacharya N, Yuan RT, Hotson AN, Finck R, Carmi Y, Zunder ER, Fantl WJ, Bendall SC, Engleman EG, Nolan GP. Spitzer MH, et al. Among authors: engleman eg. Science. 2015 Jul 10;349(6244):1259425. doi: 10.1126/science.1259425. Science. 2015. PMID: 26160952 Free PMC article.
Normalizing Microbiota-Induced Retinoic Acid Deficiency Stimulates Protective CD8(+) T Cell-Mediated Immunity in Colorectal Cancer.
Bhattacharya N, Yuan R, Prestwood TR, Penny HL, DiMaio MA, Reticker-Flynn NE, Krois CR, Kenkel JA, Pham TD, Carmi Y, Tolentino L, Choi O, Hulett R, Wang J, Winer DA, Napoli JL, Engleman EG. Bhattacharya N, et al. Among authors: engleman eg. Immunity. 2016 Sep 20;45(3):641-655. doi: 10.1016/j.immuni.2016.08.008. Epub 2016 Aug 30. Immunity. 2016. PMID: 27590114 Free PMC article.
Akt and SHP-1 are DC-intrinsic checkpoints for tumor immunity.
Carmi Y, Prestwood TR, Spitzer MH, Linde IL, Chabon J, Reticker-Flynn NE, Bhattacharya N, Zhang H, Zhang X, Basto PA, Burt BM, Alonso MN, Engleman EG. Carmi Y, et al. Among authors: engleman eg. JCI Insight. 2016 Nov 3;1(18):e89020. doi: 10.1172/jci.insight.89020. JCI Insight. 2016. PMID: 27812544 Free PMC article.
Systemic Immunity Is Required for Effective Cancer Immunotherapy.
Spitzer MH, Carmi Y, Reticker-Flynn NE, Kwek SS, Madhireddy D, Martins MM, Gherardini PF, Prestwood TR, Chabon J, Bendall SC, Fong L, Nolan GP, Engleman EG. Spitzer MH, et al. Among authors: engleman eg. Cell. 2017 Jan 26;168(3):487-502.e15. doi: 10.1016/j.cell.2016.12.022. Epub 2017 Jan 19. Cell. 2017. PMID: 28111070 Free PMC article.
308 results