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Low-dose prednisolone in early rheumatoid arthritis inhibits collagen type I degradation by matrix metalloproteinases as assessed by serum 1CTP--a possible mechanism for specific inhibition of radiological destruction.
Engvall IL, Svensson B, Boonen A, van der Heijde D, Lerner UH, Hafström I; BARFOT study group. Engvall IL, et al. Rheumatology (Oxford). 2013 Apr;52(4):733-42. doi: 10.1093/rheumatology/kes369. Epub 2012 Dec 28. Rheumatology (Oxford). 2013. PMID: 23275387 Clinical Trial.