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| Year | Number of Results |
|---|---|
| 1994 | 1 |
| 1997 | 1 |
| 1998 | 3 |
| 1999 | 2 |
| 2000 | 2 |
| 2002 | 1 |
| 2003 | 1 |
| 2006 | 4 |
| 2007 | 1 |
| 2008 | 2 |
| 2011 | 2 |
| 2013 | 2 |
| 2015 | 1 |
| 2018 | 1 |
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| 2021 | 1 |
| 2026 | 0 |
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Biological drug and drug delivery-mediated immunotherapy.
Acta Pharm Sin B. 2021 Apr;11(4):941-960. doi: 10.1016/j.apsb.2020.12.018. Epub 2020 Dec 31.
Acta Pharm Sin B. 2021.
PMID: 33996408
Free PMC article.
Review.
Herein, we reviewed the potential targets for immunotherapy against the major inflammatory diseases, discussed the biologics and drug delivery systems involved in the immunotherapy, particularly highlighted the approved therapy tactics, and finally offer perspectives in th …
Herein, we reviewed the potential targets for immunotherapy against the major inflammatory diseases, discussed the biologics and drug delive …
Enhanced antitumoral effect of adenovirus-mediated cytosine deaminase gene therapy by induction of antigen-presenting cells through stem cell factor/granulocyte-macrophage colony-stimulating factor gene transfer.
Cancer Gene Ther. 2000 Feb;7(2):177-86. doi: 10.1038/sj.cgt.7700114.
Cancer Gene Ther. 2000.
PMID: 10770625
To address the drawbacks of the limited potential for the induction of antitumoral immunity by CD suicide gene therapy, we hypothesized that antigen-presenting cells (APCs) might contribute to the efficient induction of an antitumoral …
To address the drawbacks of the limited potential for the induction of antitumoral immunity by CD suicide gene therapy, …
Activities of granulocyte-macrophage colony-stimulating factor revealed by gene transfer and gene knockout studies.
Stem Cells. 1994;12 Suppl 1:173-82; discussion 182-4.
Stem Cells. 1994.
PMID: 7696961
Review.
We used retroviral mediated gene transfer and gene knockout technologies to explore the in vivo functions of murine granulocyte-macrophage colony-stimulating factor (GM-CSF) [1, 2]. ...Vaccination required activities …
We used retroviral mediated gene transfer and gene knockout technologies to explore the in vivo functions of mur …
Therapeutic gene modified cell based cancer vaccines.
Gene. 2013 Aug 10;525(2):200-7. doi: 10.1016/j.gene.2013.03.056. Epub 2013 Apr 6.
Gene. 2013.
PMID: 23566846
Review.
Interactions between cancer and stroma cells create network of immunosuppressive pathways, while activation of immune defense is inhibited. ...This review presents the progress and breakthroughs in design, development and clinical application of selected cell-based …
Interactions between cancer and stroma cells create network of immunosuppressive pathways, while activation of immune defense is inhi …
Generation of GM-CSF-producing antigen-presenting cells that induce a cytotoxic T cell-mediated antitumor response.
Oncoimmunology. 2020 Sep 6;9(1):1814620. doi: 10.1080/2162402X.2020.1814620.
Oncoimmunology. 2020.
PMID: 33457097
Free PMC article.
We previously generated proliferating antigen-presenting cells (APCs) by genetically engineering myeloid cells derived from induced pluripotent stem cells (iPSC-pMCs), which offer infinite functional APCs for broad applications in cancer …
We previously generated proliferating antigen-presenting cells (APCs) by genetically engineering myeloid cells d …
High efficiency adenovirus-mediated gene transfer to human dendritic cells.
Blood. 1998 Jan 15;91(2):392-8.
Blood. 1998.
PMID: 9427691
Free article.
To extend the range of methods available, we generated phenotypically characteristic dendritic cells from peripheral blood monocytes incubated with granulocyte-macrophage colony-stimulating factor and interleukin-4 and infected the …
To extend the range of methods available, we generated phenotypically characteristic dendritic cells from peripheral blood monocytes …
Gene transfer into human dendritic antigen-presenting cells by vaccinia virus and adenovirus vectors.
Cancer Gene Ther. 1998 Nov-Dec;5(6):350-6.
Cancer Gene Ther. 1998.
PMID: 9917089
DCs were generated ex vivo in the presence of tumor necrosis factor-alpha, granulocyte macrophage colony-stimulating factor, stem cell factor, and flk-2/flt-3 ligand taken from CD34+ hematopoietic progenitors that wer …
DCs were generated ex vivo in the presence of tumor necrosis factor-alpha, granulocyte macrophage colony-stim …
Generation and genetic modification of dendritic cells derived from mouse embryonic stem cells.
Blood. 2003 May 1;101(9):3501-8. doi: 10.1182/blood-2002-07-2254. Epub 2002 Oct 24.
Blood. 2003.
PMID: 12406878
Free article.
We developed a method to generate dendritic cells (DCs) from mouse embryonic stem (ES) cells. We cultured ES cells for 10 days on feeder cell layers of OP9, in the presence of granulocyte-macrophage colony-stimulating …
We developed a method to generate dendritic cells (DCs) from mouse embryonic stem (ES) cells. We cultured ES cells …
Treatment of pulmonary metastatic tumors in mice using lentiviral vector-engineered stem cells.
Cancer Gene Ther. 2008 Feb;15(2):73-84. doi: 10.1038/sj.cgt.7701108. Epub 2007 Dec 14.
Cancer Gene Ther. 2008.
PMID: 18084244
Free PMC article.
We have previously demonstrated that lentiviral vector-mediated transgene delivery to DC progenitors, including bone marrow cells and hematopoietic stem cells, followed by transplantation supports systemic generation of great numbers of tumor antige …
We have previously demonstrated that lentiviral vector-mediated transgene delivery to DC progenitors, including bone marrow cells …
Lentiviral vectors for induction of self-differentiation and conditional ablation of dendritic cells.
Gene Ther. 2011 Aug;18(8):750-64. doi: 10.1038/gt.2011.15. Epub 2011 Mar 17.
Gene Ther. 2011.
PMID: 21412283
Free PMC article.
Development of lentiviral vectors (LVs) in the field of immunotherapy and immune regeneration will strongly rely on biosafety of the gene transfer. We demonstrated previously the feasibility of ex vivo genetic programming of mouse bone marrow precursors with …
Development of lentiviral vectors (LVs) in the field of immunotherapy and immune regeneration will strongly rely on biosafety of the gene …
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