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Role of nitric oxide in shock: the large animal perspective.
Lange M, Enkhbaatar P, Nakano Y, Traber DL. Lange M, et al. Front Biosci (Landmark Ed). 2009 Jan 1;14:1979-89. doi: 10.2741/3357. Front Biosci (Landmark Ed). 2009. PMID: 19273179 Review.
P-selectin blockade fails to improve acute lung injury in sheep.
Chandra A, Katahira J, Schmalstieg FC, Murakami K, Enkhbaatar P, Cox RA, Hawkins HK, Traber LD, Herndon DN, Traber DL. Chandra A, et al. Clin Sci (Lond). 2003 Mar;104(3):313-21. doi: 10.1042/CS20020244. Clin Sci (Lond). 2003. PMID: 12605592
This initial recruitment of neutrophils within the pulmonary microvasculature may involve P-selectin. Thus we hypothesized that an antibody against P-selectin would reduce pulmonary damage. ...The first group received 40% body surface area third-degree burns with 48 …
This initial recruitment of neutrophils within the pulmonary microvasculature may involve P-selectin. Thus we hypothesized that an an …
Effect of poly(ADP ribose) synthetase inhibition on burn and smoke inhalation injury in sheep.
Shimoda K, Murakami K, Enkhbaatar P, Traber LD, Cox RA, Hawkins HK, Schmalstieg FC, Komjati K, Mabley JG, Szabo C, Salzman AL, Traber DL. Shimoda K, et al. Am J Physiol Lung Cell Mol Physiol. 2003 Jul;285(1):L240-9. doi: 10.1152/ajplung.00319.2002. Epub 2003 Mar 7. Am J Physiol Lung Cell Mol Physiol. 2003. PMID: 12626333
High-dose heparin fails to improve acute lung injury following smoke inhalation in sheep.
Murakami K, Enkhbaatar P, Shimoda K, Mizutani A, Cox RA, Schmalstieg FC, Jodoin JM, Hawkins HK, Traber LD, Traber DL. Murakami K, et al. Clin Sci (Lond). 2003 Apr;104(4):349-56. Clin Sci (Lond). 2003. PMID: 12653676
The inducible nitric oxide synthase inhibitor BBS-2 prevents acute lung injury in sheep after burn and smoke inhalation injury.
Enkhbaatar P, Murakami K, Shimoda K, Mizutani A, Traber L, Phillips GB, Parkinson JF, Cox R, Hawkins H, Herndon D, Traber D. Enkhbaatar P, et al. Am J Respir Crit Care Med. 2003 Apr 1;167(7):1021-6. doi: 10.1164/rccm.200209-1031PP. Am J Respir Crit Care Med. 2003. PMID: 12663341
Inhibition of neuronal nitric oxide synthase by 7-nitroindazole attenuates acute lung injury in an ovine model.
Enkhbaatar P, Murakami K, Shimoda K, Mizutani A, McGuire R, Schmalstieg F, Cox R, Hawkins H, Jodoin J, Lee S, Traber L, Herndon D, Traber D. Enkhbaatar P, et al. Am J Physiol Regul Integr Comp Physiol. 2003 Aug;285(2):R366-72. doi: 10.1152/ajpregu.00148.2003. Epub 2003 May 22. Am J Physiol Regul Integr Comp Physiol. 2003. PMID: 12763743
Ketorolac attenuates cardiopulmonary derangements in sheep with combined burn and smoke inhalation injury.
Enkhbaatar P, Murakami K, Shimoda K, Salsbury J, Cox R, Hawkins H, Traber L, Herndon D, Traber D. Enkhbaatar P, et al. Clin Sci (Lond). 2003 Nov;105(5):621-8. doi: 10.1042/CS20030180. Clin Sci (Lond). 2003. PMID: 12882643
Pyridoxalated haemoglobin polyoxyethylene conjugate, a nitric oxide scavenger, decreases dose-limiting hypotension associated with interleukin-2 (IL-2) therapy.
Murakami K, Privalle C, Enkhbaatar P, Shimoda K, Schmalstieg FC, Deangelo J, Lee S, Traber LD, Traber DL. Murakami K, et al. Clin Sci (Lond). 2003 Nov;105(5):629-35. doi: 10.1042/CS20030164. Clin Sci (Lond). 2003. PMID: 12895141
Inducible nitric oxide synthase dimerization inhibitor prevents cardiovascular and renal morbidity in sheep with combined burn and smoke inhalation injury.
Enkhbaatar P, Murakami K, Shimoda K, Mizutani A, Traber L, Phillips G, Parkinson J, Salsbury JR, Biondo N, Schmalstieg F, Burke A, Cox R, Hawkins H, Herndon D, Traber D. Enkhbaatar P, et al. Am J Physiol Heart Circ Physiol. 2003 Dec;285(6):H2430-6. doi: 10.1152/ajpheart.00055.2003. Epub 2003 Aug 14. Am J Physiol Heart Circ Physiol. 2003. PMID: 12919929
Carboxyhemoglobin formation following smoke inhalation injury in sheep is interrelated with pulmonary shunt fraction.
Westphal M, Morita N, Enkhbaatar P, Murakami K, Traber L, Traber DL. Westphal M, et al. Biochem Biophys Res Commun. 2003 Nov 21;311(3):754-8. doi: 10.1016/j.bbrc.2003.10.063. Biochem Biophys Res Commun. 2003. PMID: 14623337
This approach resulted in a progressive increase in COHb formation that was interrelated with the degree of Qs/Qt (P<0.001) and inversely correlated with both arterial and mixed venous HbO(2) saturation (r=-0.96 and -0.93). ...
This approach resulted in a progressive increase in COHb formation that was interrelated with the degree of Qs/Qt (P<0.001) and in …
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