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Spontaneous object recognition and object location memory in rats: the effects of lesions in the cingulate cortices, the medial prefrontal cortex, the cingulum bundle and the fornix.
Ennaceur A, Neave N, Aggleton JP. Ennaceur A, et al. Exp Brain Res. 1997 Mar;113(3):509-19. doi: 10.1007/pl00005603. Exp Brain Res. 1997. PMID: 9108217
The first experiment assessed the effects of neurotoxic lesions in either the anterior cingulate cortex (ACc) or the retrosplenial cortex (RSc) on a test of object recognition. ...The latter task also used a preference measure, but in this case it concerned preferen …
The first experiment assessed the effects of neurotoxic lesions in either the anterior cingulate cortex (ACc) or the retrosplenial cortex (R …
Slope climbing challenges, fear of heights, anxiety and time of the day.
Ennaceur A, Hussain MD, Abuhamdah RM, Mostafa RM, Chazot PL. Ennaceur A, et al. Behav Brain Res. 2017 Jan 1;316:169-182. doi: 10.1016/j.bbr.2016.09.010. Epub 2016 Sep 5. Behav Brain Res. 2017. PMID: 27609646
Omission of the habituation procedure in the acquisition of a working memory task - evidence from Balb/c, C57/BL6J, and CD-1 mice.
Ennaceur A. Ennaceur A. Behav Brain Res. 2011 Sep 30;223(1):203-10. doi: 10.1016/j.bbr.2011.04.035. Epub 2011 Apr 27. Behav Brain Res. 2011. PMID: 21549759
In the present study, C57, CD-1 and Balb/c mice were introduced to a working memory task in a radial-arm maze without habituation. Fear-induced anxiety from exposure to the novelty in this maze is demonstrated by a very low number of arm entries. Animals have …
In the present study, C57, CD-1 and Balb/c mice were introduced to a working memory task in a radial-arm maze without habituat …
Tolerance, sensitization and dependence to diazepam in Balb/c mice exposed to a novel open space anxiety test.
Ennaceur A, Michalikova S, van Rensburg R, Chazot PL. Ennaceur A, et al. Behav Brain Res. 2010 May 1;209(1):154-64. doi: 10.1016/j.bbr.2010.01.039. Epub 2010 Feb 1. Behav Brain Res. 2010. PMID: 20117142
All groups of mice received a single dose of DZP (1mg/kg) in session 6. DZP produced inverted U-shaped dose-responses on the number of entries into different areas of the apparatus, with a peak in mean response at 1mg/kg whereas its effect on the duration of entries …
All groups of mice received a single dose of DZP (1mg/kg) in session 6. DZP produced inverted U-shaped dose-responses on the number o …
Distinguishing anxiolysis and hyperactivity in an open space behavioral test.
Ennaceur A, Michalikova S, van Rensburg R, Chazot PL. Ennaceur A, et al. Behav Brain Res. 2010 Feb 11;207(1):84-98. doi: 10.1016/j.bbr.2009.09.042. Epub 2009 Oct 2. Behav Brain Res. 2010. PMID: 19800918
Amphetamine and diazepam produced an inverted U-shaped dose-response effect on different parameters of the test and demonstrate that the drug concentration which elicited a peak in mean number of entries is different from the drug concentration which elicited a peak …
Amphetamine and diazepam produced an inverted U-shaped dose-response effect on different parameters of the test and demonstrate that the dru …
Are benzodiazepines really anxiolytic? Evidence from a 3D maze spatial navigation task.
Ennaceur A, Michalikova S, van Rensburg R, Chazot PL. Ennaceur A, et al. Behav Brain Res. 2008 Mar 17;188(1):136-53. doi: 10.1016/j.bbr.2007.10.026. Epub 2007 Nov 1. Behav Brain Res. 2008. PMID: 18055029
The effects of diazepam and chlordiazepoxide were assessed in a 3D maze which is a modification of an 8-arm radial maze. Each arm of the maze is attached to a bridge radiating from a central platform. Animals exposed for the first time to the maze do n …
The effects of diazepam and chlordiazepoxide were assessed in a 3D maze which is a modification of an 8-arm radial maze. Each …
Models of anxiety: responses of rats to novelty in an open space and an enclosed space.
Ennaceur A, Michalikova S, Chazot PL. Ennaceur A, et al. Behav Brain Res. 2006 Jul 15;171(1):26-49. doi: 10.1016/j.bbr.2006.03.016. Epub 2006 May 4. Behav Brain Res. 2006. PMID: 16678277
Exposure to novelty has been shown to induce anxiety responses in a variety of behavioural paradigms. The purpose of the present study was to investigate whether exposition of naïve rats to novelty would result in a comparable or a different pattern of respon …
Exposure to novelty has been shown to induce anxiety responses in a variety of behavioural paradigms. The purpose of the present stud …
Models of anxiety: responses of mice to novelty and open spaces in a 3D maze.
Ennaceur A, Michalikova S, van Rensburg R, Chazot PL. Ennaceur A, et al. Behav Brain Res. 2006 Nov 1;174(1):9-38. doi: 10.1016/j.bbr.2006.07.001. Epub 2006 Aug 17. Behav Brain Res. 2006. PMID: 16919819
The present report describes the emotional responses of different strains of mice to exposure to a novel open space model of anxiety using a 3D spatial navigation task. The 3D maze is modification of the radial maze with flexible arms that can be raised above or low …
The present report describes the emotional responses of different strains of mice to exposure to a novel open space model of anxiety …
Pre-training in a radial arm maze abolished anxiety and impaired habituation in C57BL6/J mice treated with dizocilpine.
Abuhamdah RM, Hussain MD, Chazot PL, Ennaceur A. Abuhamdah RM, et al. Among authors: ennaceur a. Physiol Behav. 2016 Oct 1;164(Pt A):353-60. doi: 10.1016/j.physbeh.2016.06.017. Epub 2016 Jun 16. Physiol Behav. 2016. PMID: 27317838
One-trial object recognition in rats and mice: methodological and theoretical issues.
Ennaceur A. Ennaceur A. Behav Brain Res. 2010 Dec 31;215(2):244-54. doi: 10.1016/j.bbr.2009.12.036. Epub 2010 Jan 7. Behav Brain Res. 2010. PMID: 20060020 Review.
The one-trial object recognition task involves memory of a familiar object in parallel with the detection and encoding of a novel object. It provides the basis for the study of a wide range of cognitive and neuropsychological functions and processes in rats a …
The one-trial object recognition task involves memory of a familiar object in parallel with the detection and encoding of a no …
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