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Overexpression of the human manganese superoxide dismutase (MnSOD) transgene in subclones of murine hematopoietic progenitor cell line 32D cl 3 decreases irradiation-induced apoptosis but does not alter G2/M or G1/S phase cell cycle arrest.
Epperly MW, Bray JA, Esocobar P, Bigbee WL, Watkins S, Greenberger JS. Epperly MW, et al. Radiat Oncol Investig. 1999;7(6):331-42. doi: 10.1002/(SICI)1520-6823(1999)7:6<331::AID-ROI3>3.0.CO;2-M. Radiat Oncol Investig. 1999. PMID: 10644056
Considerations in optimizing radiation therapy for non-small cell lung cancer.
Greenberger JS, Bahri S, Jett J, Belani C, Kalend A, Epperly M. Greenberger JS, et al. Chest. 1998 Jan;113(1 Suppl):46S-52S. doi: 10.1378/chest.113.1_supplement.46s. Chest. 1998. PMID: 9438690 Review.
Pharmacologic profiling of phosphoinositide 3-kinase inhibitors as mitigators of ionizing radiation-induced cell death.
Lazo JS, Sharlow ER, Epperly MW, Lira A, Leimgruber S, Skoda EM, Wipf P, Greenberger JS. Lazo JS, et al. J Pharmacol Exp Ther. 2013 Dec;347(3):669-80. doi: 10.1124/jpet.113.208421. Epub 2013 Sep 25. J Pharmacol Exp Ther. 2013. PMID: 24068833 Free PMC article.
Radioresistant human lung adenocarcinoma cells that survived multiple fractions of ionizing radiation are sensitive to HSP90 inhibition.
Gomez-Casal R, Epperly MW, Wang H, Proia DA, Greenberger JS, Levina V. Gomez-Casal R, et al. Oncotarget. 2015 Dec 29;6(42):44306-22. doi: 10.18632/oncotarget.6248. Oncotarget. 2015. PMID: 26517240 Free PMC article.
Human in vivo radiation-induced biomarkers: gene expression changes in radiotherapy patients.
Amundson SA, Grace MB, McLeland CB, Epperly MW, Yeager A, Zhan Q, Greenberger JS, Fornace AJ Jr. Amundson SA, et al. Cancer Res. 2004 Sep 15;64(18):6368-71. doi: 10.1158/0008-5472.CAN-04-1883. Cancer Res. 2004. PMID: 15374940
Improved Total-Body Irradiation Survival by Delivery of Two Radiation Mitigators that Target Distinct Cell Death Pathways.
Steinman J, Epperly M, Hou W, Willis J, Wang H, Fisher R, Liu B, Bahar I, McCaw T, Kagan V, Bayir H, Yu J, Wipf P, Li S, Huq MS, Greenberger JS. Steinman J, et al. Radiat Res. 2018 Jan;189(1):68-83. doi: 10.1667/RR14787.1. Epub 2017 Nov 15. Radiat Res. 2018. PMID: 29140165 Free PMC article.
Pharmacologically blocking p53-dependent apoptosis protects intestinal stem cells and mice from radiation.
Wang X, Wei L, Cramer JM, Leibowitz BJ, Judge C, Epperly M, Greenberger J, Wang F, Li L, Stelzner MG, Dunn JCY, Martin MG, Lagasse E, Zhang L, Yu J. Wang X, et al. Sci Rep. 2015 Apr 10;5:8566. doi: 10.1038/srep08566. Sci Rep. 2015. PMID: 25858503 Free PMC article.
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