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2000 14
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2,687 results

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Equipoise and the ethics of clinical research.
Freedman B. Freedman B. N Engl J Med. 1987 Jul 16;317(3):141-5. doi: 10.1056/NEJM198707163170304. N Engl J Med. 1987. PMID: 3600702
The ethics of clinical research requires equipoise--a state of genuine uncertainty on the part of the clinical investigator regarding the comparative therapeutic merits of each arm in a trial. ...According to this concept of "clinical equipoise," the requirement is …
The ethics of clinical research requires equipoise--a state of genuine uncertainty on the part of the clinical investigator regarding …
Clinical Equipoise.
Benzel E. Benzel E. World Neurosurg. 2021 Sep;153:xiii. doi: 10.1016/j.wneu.2021.07.008. World Neurosurg. 2021. PMID: 34420778 No abstract available.
Equipoise: Where does it stand in current clinical research.
Panda S, Das A. Panda S, et al. Indian J Dermatol Venereol Leprol. 2022 Mar-Apr;88(2):135-136. doi: 10.25259/IJDVL_1163_20. Indian J Dermatol Venereol Leprol. 2022. PMID: 34877839 Free article. Review. No abstract available.
Glycemic equipoise.
Kalra S, John M, Unnikrishnan AG. Kalra S, et al. Indian J Endocrinol Metab. 2017 Jan-Feb;21(1):18-20. doi: 10.4103/2230-8210.194361. Indian J Endocrinol Metab. 2017. PMID: 28217492 Free PMC article. No abstract available.
Review of Clinical Equipoise: Examples from Oncology Trials.
AlHamaly MA, Alzoubi KH, Khabour OF, Jaber RA, Aldelaimy WK. AlHamaly MA, et al. Curr Rev Clin Exp Pharmacol. 2023;18(1):22-30. doi: 10.2174/2772432817666211221164101. Curr Rev Clin Exp Pharmacol. 2023. PMID: 34939559 Free PMC article. Review.
The term clinical equipoise was proposed to provide an ethical ground to conduct randomized controlled clinical trials. ...RESULTS: The concept of clinical equipoise has been challenged, and different alternatives were proposed. Yet, these alternatives received nume …
The term clinical equipoise was proposed to provide an ethical ground to conduct randomized controlled clinical trials. ...RESULTS: T …
Equipoise in the management of intracranial aneurysms.
Howard BM, Zelmanovich R, Dawoud RA, Barrow DL. Howard BM, et al. Neurosurg Focus. 2025 Dec 1;59(6):E3. doi: 10.3171/2025.9.FOCUS25767. Neurosurg Focus. 2025. PMID: 41343788 Review.
The evidence to support EVT or surgical management of aneurysms is critically reviewed in the context of equipoise, a genuine state of uncertainty regarding the superiority of one therapeutic modality over another. ...Rather, it is a call for balance, for a recalibration o …
The evidence to support EVT or surgical management of aneurysms is critically reviewed in the context of equipoise, a genuine state o …
Understanding Equipoise.
Hoffer LJ. Hoffer LJ. Nutr Clin Pract. 2020 Jun;35(3):495-498. doi: 10.1002/ncp.10492. Epub 2020 Apr 29. Nutr Clin Pract. 2020. PMID: 32347586 No abstract available.
Equipoise and the RCT.
Braakhekke M, Mol F, Mastenbroek S, Mol BW, van der Veen F. Braakhekke M, et al. Hum Reprod. 2017 Feb;32(2):257-260. doi: 10.1093/humrep/dew286. Epub 2016 Nov 14. Hum Reprod. 2017. PMID: 28119447 Free article. Review.
A key concept underpinning the ethics of RCTs is equipoise. Here, we aimed to dissect the basic reasoning behind the concept of equipoise and we proposed a line of thinking delineating under which conditions it is ethical to design and execute an RCT. ...
A key concept underpinning the ethics of RCTs is equipoise. Here, we aimed to dissect the basic reasoning behind the concept of eq …
Ethical Considerations and Equipoise in Cancer Surgery.
Vakili-Ojarood M, Naseri A, Shirinzadeh-Dastgiri A, Saberi A, HaghighiKian SM, Rahmani A, Farnoush N, Nafissi N, Heiranizadeh N, Antikchi MH, Narimani N, Atarod MM, Yeganegi M, Neamatzadeh H. Vakili-Ojarood M, et al. Indian J Surg Oncol. 2024 Sep;15(Suppl 3):363-373. doi: 10.1007/s13193-024-02023-8. Epub 2024 Jul 12. Indian J Surg Oncol. 2024. PMID: 39328740 Free PMC article. Review.
In this study, we thoroughly analyzed previous scholarly works on ethical considerations and equipoise in the field of oncological surgery. Our main focus was on the use of AI in this specific context....
In this study, we thoroughly analyzed previous scholarly works on ethical considerations and equipoise in the field of oncological su …
Equipoise in pediatric acute liver failure.
Chapin CA, Squires JE, Horslen SP, Alonso EM. Chapin CA, et al. J Pediatr Gastroenterol Nutr. 2024 May;78(5):1001-1004. doi: 10.1002/jpn3.12166. Epub 2024 Feb 26. J Pediatr Gastroenterol Nutr. 2024. PMID: 38409886 No abstract available.
2,687 results