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An Alphavirus-derived replicon RNA vaccine induces SARS-CoV-2 neutralizing antibody and T cell responses in mice and nonhuman primates.
Erasmus JH, Khandhar AP, O'Connor MA, Walls AC, Hemann EA, Murapa P, Archer J, Leventhal S, Fuller JT, Lewis TB, Draves KE, Randall S, Guerriero KA, Duthie MS, Carter D, Reed SG, Hawman DW, Feldmann H, Gale M Jr, Veesler D, Berglund P, Fuller DH. Erasmus JH, et al. Sci Transl Med. 2020 Aug 5;12(555):eabc9396. doi: 10.1126/scitranslmed.abc9396. Epub 2020 Jul 20. Sci Transl Med. 2020. PMID: 32690628 Free PMC article.
Single-dose replicating RNA vaccine induces neutralizing antibodies against SARS-CoV-2 in nonhuman primates.
Erasmus JH, Khandhar AP, Walls AC, Hemann EA, O'Connor MA, Murapa P, Archer J, Leventhal S, Fuller J, Lewis T, Draves KE, Randall S, Guerriero KA, Duthie MS, Carter D, Reed SG, Hawman DW, Feldmann H, Gale M, Veesler D, Berglund P, Fuller DH. Erasmus JH, et al. bioRxiv [Preprint]. 2020 May 28:2020.05.28.121640. doi: 10.1101/2020.05.28.121640. bioRxiv. 2020. PMID: 32511417 Free PMC article. Preprint.
Preparing for Pandemics: RNA Vaccines at the Forefront.
Erasmus JH, Fuller DH. Erasmus JH, et al. Mol Ther. 2020 Jul 8;28(7):1559-1560. doi: 10.1016/j.ymthe.2020.06.017. Epub 2020 Jun 23. Mol Ther. 2020. PMID: 32579882 Free PMC article. No abstract available.
Intramuscular Delivery of Replicon RNA Encoding ZIKV-117 Human Monoclonal Antibody Protects against Zika Virus Infection.
Erasmus JH, Archer J, Fuerte-Stone J, Khandhar AP, Voigt E, Granger B, Bombardi RG, Govero J, Tan Q, Durnell LA, Coler RN, Diamond MS, Crowe JE Jr, Reed SG, Thackray LB, Carnahan RH, Van Hoeven N. Erasmus JH, et al. Mol Ther Methods Clin Dev. 2020 Jun 18;18:402-414. doi: 10.1016/j.omtm.2020.06.011. eCollection 2020 Sep 11. Mol Ther Methods Clin Dev. 2020. PMID: 32695842 Free PMC article.
Integrated pipeline for the accelerated discovery of antiviral antibody therapeutics.
Gilchuk P, Bombardi RG, Erasmus JH, Tan Q, Nargi R, Soto C, Abbink P, Suscovich TJ, Durnell LA, Khandhar A, Archer J, Liang J, Fouch ME, Davidson E, Doranz BJ, Jones T, Larson E, Ertel S, Granger B, Fuerte-Stone J, Roy V, Broge T, Linnekin TC, Linde CH, Gorman MJ, Nkolola J, Alter G, Reed SG, Barouch DH, Diamond MS, Crowe JE Jr, Van Hoeven N, Thackray LB, Carnahan RH. Gilchuk P, et al. Among authors: erasmus jh. Nat Biomed Eng. 2020 Nov;4(11):1030-1043. doi: 10.1038/s41551-020-0594-x. Epub 2020 Aug 3. Nat Biomed Eng. 2020. PMID: 32747832 Free PMC article.
SARS-CoV2 variant-specific replicating RNA vaccines protect from disease and pathology and reduce viral shedding following challenge with heterologous SARS-CoV2 variants of concern.
Hawman DW, Meade-White K, Archer J, Leventhal S, Wilson D, Shaia C, Randall S, Khandhar AP, Hsiang TY, Gale M Jr, Berglund P, Fuller DH, Feldmann H, Erasmus JH. Hawman DW, et al. Among authors: erasmus jh. bioRxiv [Preprint]. 2021 Dec 13:2021.12.10.472134. doi: 10.1101/2021.12.10.472134. bioRxiv. 2021. PMID: 34931189 Free PMC article. Updated. Preprint.
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