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Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton.
Sarbassov DD, Ali SM, Kim DH, Guertin DA, Latek RR, Erdjument-Bromage H, Tempst P, Sabatini DM. Sarbassov DD, et al. Curr Biol. 2004 Jul 27;14(14):1296-302. doi: 10.1016/j.cub.2004.06.054. Curr Biol. 2004. PMID: 15268862
GbetaL, a positive regulator of the rapamycin-sensitive pathway required for the nutrient-sensitive interaction between raptor and mTOR.
Kim DH, Sarbassov DD, Ali SM, Latek RR, Guntur KV, Erdjument-Bromage H, Tempst P, Sabatini DM. Kim DH, et al. Mol Cell. 2003 Apr;11(4):895-904. doi: 10.1016/s1097-2765(03)00114-x. Mol Cell. 2003. PMID: 12718876
mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery.
Kim DH, Sarbassov DD, Ali SM, King JE, Latek RR, Erdjument-Bromage H, Tempst P, Sabatini DM. Kim DH, et al. Cell. 2002 Jul 26;110(2):163-75. doi: 10.1016/s0092-8674(02)00808-5. Cell. 2002. PMID: 12150925
The core of the polycomb repressive complex is compositionally and functionally conserved in flies and humans.
Levine SS, Weiss A, Erdjument-Bromage H, Shao Z, Tempst P, Kingston RE. Levine SS, et al. Mol Cell Biol. 2002 Sep;22(17):6070-8. doi: 10.1128/mcb.22.17.6070-6078.2002. Mol Cell Biol. 2002. PMID: 12167701 Free PMC article.
DAPP1 undergoes a PI 3-kinase-dependent cycle of plasma-membrane recruitment and endocytosis upon cell stimulation.
Anderson KE, Lipp P, Bootman M, Ridley SH, Coadwell J, Rönnstrand L, Lennartsson J, Holmes AB, Painter GF, Thuring J, Lim Z, Erdjument-Bromage H, Grewal A, Tempst P, Stephens LR, Hawkins PT. Anderson KE, et al. Curr Biol. 2000 Nov 16;10(22):1403-12. doi: 10.1016/s0960-9822(00)00794-6. Curr Biol. 2000. PMID: 11102801
A novel Rad24 checkpoint protein complex closely related to replication factor C.
Green CM, Erdjument-Bromage H, Tempst P, Lowndes NF. Green CM, et al. Curr Biol. 2000 Jan 13;10(1):39-42. doi: 10.1016/s0960-9822(99)00263-8. Curr Biol. 2000. PMID: 10660302
Human Mob proteins regulate the NDR1 and NDR2 serine-threonine kinases.
Devroe E, Erdjument-Bromage H, Tempst P, Silver PA. Devroe E, et al. J Biol Chem. 2004 Jun 4;279(23):24444-51. doi: 10.1074/jbc.M401999200. Epub 2004 Apr 2. J Biol Chem. 2004. PMID: 15067004
Methylation of H3-lysine 79 is mediated by a new family of HMTases without a SET domain.
Feng Q, Wang H, Ng HH, Erdjument-Bromage H, Tempst P, Struhl K, Zhang Y. Feng Q, et al. Curr Biol. 2002 Jun 25;12(12):1052-8. doi: 10.1016/s0960-9822(02)00901-6. Curr Biol. 2002. PMID: 12123582
Synthesis of diphosphoinositol pentakisphosphate by a newly identified family of higher inositol polyphosphate kinases.
Saiardi A, Erdjument-Bromage H, Snowman AM, Tempst P, Snyder SH. Saiardi A, et al. Curr Biol. 1999 Nov 18;9(22):1323-6. doi: 10.1016/s0960-9822(00)80055-x. Curr Biol. 1999. PMID: 10574768
Purification and functional characterization of SET8, a nucleosomal histone H4-lysine 20-specific methyltransferase.
Fang J, Feng Q, Ketel CS, Wang H, Cao R, Xia L, Erdjument-Bromage H, Tempst P, Simon JA, Zhang Y. Fang J, et al. Curr Biol. 2002 Jul 9;12(13):1086-99. doi: 10.1016/s0960-9822(02)00924-7. Curr Biol. 2002. PMID: 12121615
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