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Nef-specific CD45RA+ CD8+ T cells secreting MIP-1beta but not IFN-gamma are associated with nonprogressive HIV-1 infection.
Dembek CJ, Kutscher S, Heltai S, Allgayer S, Biswas P, Ghezzi S, Vicenzi E, Hoffmann D, Reitmeir P, Tambussi G, Bogner JR, Lusso P, Stellbrink HJ, Santagostino E, Vollbrecht T, Goebel FD, Protzer U, Draenert R, Tinelli M, Poli G, Erfle V, Malnati M, Cosma A. Dembek CJ, et al. Among authors: erfle v. AIDS Res Ther. 2010 Jul 2;7:20. doi: 10.1186/1742-6405-7-20. AIDS Res Ther. 2010. PMID: 20598119 Free PMC article.
The intracellular detection of MIP-1beta enhances the capacity to detect IFN-gamma mediated HIV-1-specific CD8 T-cell responses in a flow cytometric setting providing a sensitive alternative to the ELISPOT.
Kutscher S, Dembek CJ, Allgayer S, Heltai S, Stadlbauer B, Biswas P, Nozza S, Tambussi G, Bogner JR, Stellbrink HJ, Goebel FD, Lusso P, Tinelli M, Poli G, Erfle V, Pohla H, Malnati M, Cosma A. Kutscher S, et al. Among authors: erfle v. AIDS Res Ther. 2008 Oct 6;5:22. doi: 10.1186/1742-6405-5-22. AIDS Res Ther. 2008. PMID: 18837993 Free PMC article.
A new antigen scanning strategy for monitoring HIV-1 specific T-cell immune responses.
Malnati MS, Heltai S, Cosma A, Reitmeir P, Allgayer S, Glashoff RH, Liebrich W, Vardas E, Imami N, Westrop S, Nozza S, Tambussi G, Buttò S, Fanales-Belasio E, Ensoli B, Ensoli F, Tripiciano A, Fortis C, Lusso P, Poli G, Erfle V, Holmes H. Malnati MS, et al. Among authors: erfle v. J Immunol Methods. 2012 Jan 31;375(1-2):46-56. doi: 10.1016/j.jim.2011.09.005. Epub 2011 Sep 22. J Immunol Methods. 2012. PMID: 21963950
Therapeutic vaccination reduces HIV sequence variability.
Hoffmann D, Seebach J, Cosma A, Goebel FD, Strimmer K, Schätzl HM, Erfle V. Hoffmann D, et al. Among authors: erfle v. FASEB J. 2008 Feb;22(2):437-44. doi: 10.1096/fj.06-7975com. Epub 2007 Oct 10. FASEB J. 2008. PMID: 17932027
Vaccines based on Nef and on Nef/DeltaV2 Env.
Erfle V, Goebel FD, Guzman CA, Le Grand R. Erfle V, et al. Microbes Infect. 2005 Nov;7(14):1400-4. doi: 10.1016/j.micinf.2005.07.015. Epub 2005 Sep 15. Microbes Infect. 2005. PMID: 16243564 Free article.
211 results