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Functional interrogation of twenty type 2 diabetes-associated genes using isogenic human embryonic stem cell-derived β-like cells.
Xue D, Narisu N, Taylor DL, Zhang M, Grenko C, Taylor HJ, Yan T, Tang X, Sinha N, Zhu J, Vandana JJ, Nok Chong AC, Lee A, Mansell EC, Swift AJ, Erdos MR, Zhong A, Bonnycastle LL, Zhou T, Chen S, Collins FS. Xue D, et al. Among authors: mansell ec. Cell Metab. 2023 Nov 7;35(11):1897-1914.e11. doi: 10.1016/j.cmet.2023.09.013. Epub 2023 Oct 18. Cell Metab. 2023. PMID: 37858332 Free PMC article.
Functional interrogation of twenty type 2 diabetes-associated genes using isogenic hESC-derived β-like cells.
Xue D, Narisu N, Taylor DL, Zhang M, Grenko C, Taylor HJ, Yan T, Tang X, Sinha N, Zhu J, Vandana JJ, Chong ACN, Lee A, Mansell EC, Swift AJ, Erdos MR, Zhou T, Bonnycastle LL, Zhong A, Chen S, Collins FS. Xue D, et al. Among authors: mansell ec. bioRxiv [Preprint]. 2023 May 8:2023.05.07.539774. doi: 10.1101/2023.05.07.539774. bioRxiv. 2023. Update in: Cell Metab. 2023 Nov 7;35(11):1897-1914.e11. doi: 10.1016/j.cmet.2023.09.013. PMID: 37214922 Free PMC article. Updated. Preprint.
Mis-splicing drives loss of function of p53E224D point mutation.
Lock IC, Leisenring NH, Floyd W, Xu ES, Luo L, Ma Y, Mansell EC, Cardona DM, Lee CL, Kirsch DG. Lock IC, et al. Among authors: mansell ec. PLoS One. 2025 Mar 5;20(3):e0318856. doi: 10.1371/journal.pone.0318856. eCollection 2025. PLoS One. 2025. PMID: 40043089 Free PMC article.
Single-cell transcriptomic profiling of human pancreatic islets reveals genes responsive to glucose exposure over 24 h.
Grenko CM, Taylor HJ, Bonnycastle LL, Xue D, Lee BN, Weiss Z, Yan T, Swift AJ, Mansell EC, Lee A, Robertson CC, Narisu N, Erdos MR, Chen S, Collins FS, Taylor DL. Grenko CM, et al. Among authors: mansell ec. Diabetologia. 2024 Oct;67(10):2246-2259. doi: 10.1007/s00125-024-06214-4. Epub 2024 Jul 5. Diabetologia. 2024. PMID: 38967666 Free PMC article.