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Lysyl Oxidase, a Targetable Secreted Molecule Involved in Cancer Metastasis.
Cox TR, Gartland A, Erler JT. Cox TR, et al. Among authors: erler jt. Cancer Res. 2016 Jan 15;76(2):188-92. doi: 10.1158/0008-5472.CAN-15-2306. Epub 2016 Jan 5. Cancer Res. 2016. PMID: 26732355 Review.
Lysyl oxidase is essential for hypoxia-induced metastasis.
Erler JT, Bennewith KL, Nicolau M, Dornhöfer N, Kong C, Le QT, Chi JT, Jeffrey SS, Giaccia AJ. Erler JT, et al. Nature. 2006 Apr 27;440(7088):1222-6. doi: 10.1038/nature04695. Nature. 2006. PMID: 16642001 Retracted.
Lysyl oxidase mediates hypoxic control of metastasis.
Erler JT, Giaccia AJ. Erler JT, et al. Cancer Res. 2006 Nov 1;66(21):10238-41. doi: 10.1158/0008-5472.CAN-06-3197. Cancer Res. 2006. PMID: 17079439 Review.
Hypoxia-induced lysyl oxidase is a critical mediator of bone marrow cell recruitment to form the premetastatic niche.
Erler JT, Bennewith KL, Cox TR, Lang G, Bird D, Koong A, Le QT, Giaccia AJ. Erler JT, et al. Cancer Cell. 2009 Jan 6;15(1):35-44. doi: 10.1016/j.ccr.2008.11.012. Cancer Cell. 2009. PMID: 19111879 Free PMC article.
The role of tumor cell-derived connective tissue growth factor (CTGF/CCN2) in pancreatic tumor growth.
Bennewith KL, Huang X, Ham CM, Graves EE, Erler JT, Kambham N, Feazell J, Yang GP, Koong A, Giaccia AJ. Bennewith KL, et al. Among authors: erler jt. Cancer Res. 2009 Feb 1;69(3):775-84. doi: 10.1158/0008-5472.CAN-08-0987. Cancer Res. 2009. PMID: 19179545 Free PMC article.
Validation of lysyl oxidase as a prognostic marker for metastasis and survival in head and neck squamous cell carcinoma: Radiation Therapy Oncology Group trial 90-03.
Le QT, Harris J, Magliocco AM, Kong CS, Diaz R, Shin B, Cao H, Trotti A, Erler JT, Chung CH, Dicker A, Pajak TF, Giaccia AJ, Ang KK. Le QT, et al. Among authors: erler jt. J Clin Oncol. 2009 Sep 10;27(26):4281-6. doi: 10.1200/JCO.2008.20.6003. Epub 2009 Aug 10. J Clin Oncol. 2009. PMID: 19667273 Free PMC article.
Hypoxia in models of lung cancer: implications for targeted therapeutics.
Graves EE, Vilalta M, Cecic IK, Erler JT, Tran PT, Felsher D, Sayles L, Sweet-Cordero A, Le QT, Giaccia AJ. Graves EE, et al. Among authors: erler jt. Clin Cancer Res. 2010 Oct 1;16(19):4843-52. doi: 10.1158/1078-0432.CCR-10-1206. Epub 2010 Sep 21. Clin Cancer Res. 2010. PMID: 20858837 Free PMC article.
LOXL2-mediated matrix remodeling in metastasis and mammary gland involution.
Barker HE, Chang J, Cox TR, Lang G, Bird D, Nicolau M, Evans HR, Gartland A, Erler JT. Barker HE, et al. Among authors: erler jt. Cancer Res. 2011 Mar 1;71(5):1561-72. doi: 10.1158/0008-5472.CAN-10-2868. Epub 2011 Jan 13. Cancer Res. 2011. PMID: 21233336 Free PMC article.
The role of lysyl oxidase in SRC-dependent proliferation and metastasis of colorectal cancer.
Baker AM, Cox TR, Bird D, Lang G, Murray GI, Sun XF, Southall SM, Wilson JR, Erler JT. Baker AM, et al. Among authors: erler jt. J Natl Cancer Inst. 2011 Mar 2;103(5):407-24. doi: 10.1093/jnci/djq569. Epub 2011 Jan 31. J Natl Cancer Inst. 2011. PMID: 21282564
Network medicine strikes a blow against breast cancer.
Erler JT, Linding R. Erler JT, et al. Cell. 2012 May 11;149(4):731-3. doi: 10.1016/j.cell.2012.04.014. Cell. 2012. PMID: 22579276
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