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The pre-metastatic niche: is metastasis random?
Cox TR, Gartland A, Erler JT. Cox TR, et al. Among authors: erler jt. Bonekey Rep. 2012 May 2;1:80. doi: 10.1038/bonekey.2012.80. eCollection 2012. Bonekey Rep. 2012. PMID: 27127624 Free PMC article. Review.
LOX-mediated collagen crosslinking is responsible for fibrosis-enhanced metastasis.
Cox TR, Bird D, Baker AM, Barker HE, Ho MW, Lang G, Erler JT. Cox TR, et al. Among authors: erler jt. Cancer Res. 2013 Mar 15;73(6):1721-32. doi: 10.1158/0008-5472.CAN-12-2233. Epub 2013 Jan 23. Cancer Res. 2013. PMID: 23345161 Free PMC article.
Hypoxia-mediated metastasis.
Chang J, Erler J. Chang J, et al. Among authors: erler j. Adv Exp Med Biol. 2014;772:55-81. doi: 10.1007/978-1-4614-5915-6_3. Adv Exp Med Biol. 2014. PMID: 24272354 Review.
Molecular pathways: connecting fibrosis and solid tumor metastasis.
Cox TR, Erler JT. Cox TR, et al. Among authors: erler jt. Clin Cancer Res. 2014 Jul 15;20(14):3637-43. doi: 10.1158/1078-0432.CCR-13-1059. Clin Cancer Res. 2014. PMID: 25028505
Lysyl oxidase in cancer research.
Perryman L, Erler JT. Perryman L, et al. Among authors: erler jt. Future Oncol. 2014;10(9):1709-17. doi: 10.2217/fon.14.39. Future Oncol. 2014. PMID: 25145437 Review.
The hypoxic cancer secretome induces pre-metastatic bone lesions through lysyl oxidase.
Cox TR, Rumney RMH, Schoof EM, Perryman L, Høye AM, Agrawal A, Bird D, Latif NA, Forrest H, Evans HR, Huggins ID, Lang G, Linding R, Gartland A, Erler JT. Cox TR, et al. Among authors: erler jt. Nature. 2015 Jun 4;522(7554):106-110. doi: 10.1038/nature14492. Epub 2015 May 27. Nature. 2015. PMID: 26017313 Free PMC article.
Targeting the LOX/hypoxia axis reverses many of the features that make pancreatic cancer deadly: inhibition of LOX abrogates metastasis and enhances drug efficacy.
Miller BW, Morton JP, Pinese M, Saturno G, Jamieson NB, McGhee E, Timpson P, Leach J, McGarry L, Shanks E, Bailey P, Chang D, Oien K, Karim S, Au A, Steele C, Carter CR, McKay C, Anderson K, Evans TR, Marais R, Springer C, Biankin A, Erler JT, Sansom OJ. Miller BW, et al. Among authors: erler jt. EMBO Mol Med. 2015 Aug;7(8):1063-76. doi: 10.15252/emmm.201404827. EMBO Mol Med. 2015. PMID: 26077591 Free PMC article.
Hypoxia and loss of PHD2 inactivate stromal fibroblasts to decrease tumour stiffness and metastasis.
Madsen CD, Pedersen JT, Venning FA, Singh LB, Moeendarbary E, Charras G, Cox TR, Sahai E, Erler JT. Madsen CD, et al. Among authors: erler jt. EMBO Rep. 2015 Oct;16(10):1394-408. doi: 10.15252/embr.201540107. Epub 2015 Aug 31. EMBO Rep. 2015. PMID: 26323721 Free PMC article.
Targeting ECM Disrupts Cancer Progression.
Venning FA, Wullkopf L, Erler JT. Venning FA, et al. Among authors: erler jt. Front Oncol. 2015 Oct 20;5:224. doi: 10.3389/fonc.2015.00224. eCollection 2015. Front Oncol. 2015. PMID: 26539408 Free PMC article. Review.
Dataset for the proteomic inventory and quantitative analysis of the breast cancer hypoxic secretome associated with osteotropism.
Cox TR, Schoof EM, Gartland A, Erler JT, Linding R. Cox TR, et al. Among authors: erler jt. Data Brief. 2015 Oct 23;5:621-5. doi: 10.1016/j.dib.2015.09.039. eCollection 2015 Dec. Data Brief. 2015. PMID: 26649326 Free PMC article.
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