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951 results

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The following term was not found in PubMed: Zildovic
Page 1
PAX3-FOXO1 coordinates enhancer architecture, eRNA transcription, and RNA polymerase pause release at select gene targets.
Zhang S, Wang J, Liu Q, McDonald WH, Bomber ML, Layden HM, Ellis J, Borinstein SC, Hiebert SW, Stengel KR. Zhang S, et al. Mol Cell. 2022 Dec 1;82(23):4428-4442.e7. doi: 10.1016/j.molcel.2022.10.025. Epub 2022 Nov 16. Mol Cell. 2022. PMID: 36395771 Free PMC article.
By coupling rapid protein degradation with the analysis of nascent transcription over short time courses and integrating CUT&RUN, ATAC-seq, and eRNA analysis with deep proteomic analysis, we defined PAX3-FOXO1 function at a small network of direct transcriptional targe …
By coupling rapid protein degradation with the analysis of nascent transcription over short time courses and integrating CUT&RUN, ATAC-s …
Enhancer switching in cell lineage priming is linked to eRNA, Brg1's AT-hook, and SWI/SNF recruitment.
Saha D, Animireddy S, Lee J, Thommen A, Murvin MM, Lu Y, Calabrese JM, Bartholomew B. Saha D, et al. Mol Cell. 2024 May 16;84(10):1855-1869.e5. doi: 10.1016/j.molcel.2024.03.013. Epub 2024 Apr 8. Mol Cell. 2024. PMID: 38593804
RNA transcribed from enhancers, i.e., eRNA, has been suggested to directly activate transcription by recruiting transcription factors and co-activators. Although there have been specific examples of eRNA functioning in this way, it is not clear how general this may …
RNA transcribed from enhancers, i.e., eRNA, has been suggested to directly activate transcription by recruiting transcription factors …
Enhancer RNA (eRNA) in Human Diseases.
Wang Y, Zhang C, Wang Y, Liu X, Zhang Z. Wang Y, et al. Int J Mol Sci. 2022 Sep 30;23(19):11582. doi: 10.3390/ijms231911582. Int J Mol Sci. 2022. PMID: 36232885 Free PMC article. Review.
Enhancer RNAs.
Li W, Lam MT, Notani D. Li W, et al. Cell Cycle. 2014;13(20):3151-2. doi: 10.4161/15384101.2014.962860. Cell Cycle. 2014. PMID: 25485487 Free PMC article. No abstract available.
Inflammatory Immune-Associated eRNA: Mechanisms, Functions and Therapeutic Prospects.
Wan L, Li W, Meng Y, Hou Y, Chen M, Xu B. Wan L, et al. Front Immunol. 2022 Apr 19;13:849451. doi: 10.3389/fimmu.2022.849451. eCollection 2022. Front Immunol. 2022. PMID: 35514959 Free PMC article. Review.
Therefore, in this review, we summarize and discuss the relevant inflammatory roles and regulatory mechanisms of eRNAs in inflammatory immune cells, non-inflammatory immune cells, inflammatory immune diseases and tumors, and explore the potential therapeutic effects of enhancer i …
Therefore, in this review, we summarize and discuss the relevant inflammatory roles and regulatory mechanisms of eRNAs in inflammatory immun …
Enhancer RNA promotes resistance to radiotherapy in bone-metastatic prostate cancer by m6A modification.
Zhao Y, Wen S, Li H, Pan CW, Wei Y, Huang T, Li Z, Yang Y, Fan S, Zhang Y. Zhao Y, et al. Theranostics. 2023 Jan 1;13(2):596-610. doi: 10.7150/thno.78687. eCollection 2023. Theranostics. 2023. PMID: 36632223 Free PMC article.
Further data demonstrated that RNA-binding protein KHSRP recognized both m(6)A at eRNA and m(6)Am at 5'-UTR of mRNA to block RNA degradation from exoribonuclease XRN2. ...Conclusions: Our findings indicate that a bone-specific m(6)A-modified eRNA plays a vital role …
Further data demonstrated that RNA-binding protein KHSRP recognized both m(6)A at eRNA and m(6)Am at 5'-UTR of mRNA to block RNA degr …
RNA-mediated gene activation.
Jiao AL, Slack FJ. Jiao AL, et al. Epigenetics. 2014 Jan;9(1):27-36. doi: 10.4161/epi.26942. Epub 2013 Nov 1. Epigenetics. 2014. PMID: 24185374 Free PMC article. Review.
A long noncoding eRNA forms R-loops to shape emotional experience-induced behavioral adaptation.
Akiki RM, Cornbrooks RG, Magami K, Greige A, Snyder KK, Wood DJ, Herrington MC, Mace P, Blidy K, Koike N, Berto S, Cowan CW, Taniguchi M. Akiki RM, et al. Science. 2024 Dec 13;386(6727):1282-1289. doi: 10.1126/science.adp1562. Epub 2024 Dec 12. Science. 2024. PMID: 39666799
Here we show that a conserved long noncoding enhancer RNA (lnc-eRNA), transcribed from an activity-sensitive enhancer, produces DNA:RNA hybrid R-loop structures that support three-dimensional chromatin looping between enhancer and proximal promoter and rapid Npas4 gene ind …
Here we show that a conserved long noncoding enhancer RNA (lnc-eRNA), transcribed from an activity-sensitive enhancer, produces DNA:R …
eRNA binding produces tailored CBP activity profiles to regulate gene expression.
Bose DA, Berger SL. Bose DA, et al. RNA Biol. 2017 Dec 2;14(12):1655-1659. doi: 10.1080/15476286.2017.1353862. Epub 2017 Sep 26. RNA Biol. 2017. PMID: 28891741 Free PMC article. Review.
Notably, RNA binding could stimulate the core histone acetyltransferase activity of the enzyme, observable in cells as a link between eRNA production, CBP-dependent histone acetylation and expression of genes regulated by specific enhancers. ...
Notably, RNA binding could stimulate the core histone acetyltransferase activity of the enzyme, observable in cells as a link between eRN …
MUGA Scan.
Odak M, Kayani WT. Odak M, et al. 2023 Jul 25. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan–. 2023 Jul 25. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan–. PMID: 33232035 Free Books & Documents.
These include first pass, equilibrium radionucleotide angiography (ERNA), and single-photon emission computed tomography (SPECT). The first pass technique involves delivering a radioactive isotope bolus and imaging the tagged blood path as it completes initial transit thro …
These include first pass, equilibrium radionucleotide angiography (ERNA), and single-photon emission computed tomography (SPECT). The …
951 results