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The role of MLL in hematopoiesis and leukemia.
Ernst P, Wang J, Korsmeyer SJ. Ernst P, et al. Curr Opin Hematol. 2002 Jul;9(4):282-7. doi: 10.1097/00062752-200207000-00004. Curr Opin Hematol. 2002. PMID: 12042701 Review.
Conditional MLL-CBP targets GMP and models therapy-related myeloproliferative disease.
Wang J, Iwasaki H, Krivtsov A, Febbo PG, Thorner AR, Ernst P, Anastasiadou E, Kutok JL, Kogan SC, Zinkel SS, Fisher JK, Hess JL, Golub TR, Armstrong SA, Akashi K, Korsmeyer SJ. Wang J, et al. Among authors: ernst p. EMBO J. 2005 Jan 26;24(2):368-81. doi: 10.1038/sj.emboj.7600521. Epub 2005 Jan 6. EMBO J. 2005. PMID: 15635450 Free PMC article.
Cdx4 dysregulates Hox gene expression and generates acute myeloid leukemia alone and in cooperation with Meis1a in a murine model.
Bansal D, Scholl C, Fröhling S, McDowell E, Lee BH, Döhner K, Ernst P, Davidson AJ, Daley GQ, Zon LI, Gilliland DG, Huntly BJ. Bansal D, et al. Among authors: ernst p. Proc Natl Acad Sci U S A. 2006 Nov 7;103(45):16924-9. doi: 10.1073/pnas.0604579103. Epub 2006 Oct 26. Proc Natl Acad Sci U S A. 2006. PMID: 17068127 Free PMC article.
An MLL-dependent network sustains hematopoiesis.
Artinger EL, Mishra BP, Zaffuto KM, Li BE, Chung EK, Moore AW, Chen Y, Cheng C, Ernst P. Artinger EL, et al. Among authors: ernst p. Proc Natl Acad Sci U S A. 2013 Jul 16;110(29):12000-5. doi: 10.1073/pnas.1301278110. Epub 2013 Jun 6. Proc Natl Acad Sci U S A. 2013. PMID: 23744037 Free PMC article.
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