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LPS remodeling is an evolved survival strategy for bacteria.
Li Y, Powell DA, Shaffer SA, Rasko DA, Pelletier MR, Leszyk JD, Scott AJ, Masoudi A, Goodlett DR, Wang X, Raetz CR, Ernst RK. Li Y, et al. Among authors: ernst rk. Proc Natl Acad Sci U S A. 2012 May 29;109(22):8716-21. doi: 10.1073/pnas.1202908109. Epub 2012 May 14. Proc Natl Acad Sci U S A. 2012. PMID: 22586119 Free PMC article.
Small molecule adjuvants that suppress both chromosomal and mcr-1 encoded colistin-resistance and amplify colistin efficacy in polymyxin-susceptible bacteria.
Barker WT, Martin SE, Chandler CE, Nguyen TV, Harris TL, Goodell C, Melander RJ, Doi Y, Ernst RK, Melander C. Barker WT, et al. Among authors: ernst rk. Bioorg Med Chem. 2017 Oct 15;25(20):5749-5753. doi: 10.1016/j.bmc.2017.08.055. Epub 2017 Sep 9. Bioorg Med Chem. 2017. PMID: 28958847 Free PMC article.
235 results