Erythropoietin: emerging role of erythropoietin in neonatal neuroprotection.
Pediatr Neurol. 2014.
PMID: 25266611
Free PMC article.
Review.
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Erythropoietin: emerging role of erythropoietin in neonatal neuroprotection.
Pediatr Neurol. 2014 Oct;51(4):481-8. doi: 10.1016/j.pediatrneurol.2014.06.008. Epub 2014 Jun 24.
Pediatr Neurol. 2014.
PMID: 25266611
Free PMC article.
Review.
BACKGROUND: In the last two decades, there has been considerable evolution in understanding the role of erythropoietin in neuroprotection. Erythropoietin has both paracrine and autocrine functions in the brain. ...Results from phase I/II trials are pre …
BACKGROUND: In the last two decades, there has been considerable evolution in understanding the role of erythropoietin in n …
The Potential Role of Ferroptosis in Neonatal Brain Injury.
Front Neurosci. 2019 Feb 14;13:115. doi: 10.3389/fnins.2019.00115. eCollection 2019.
Front Neurosci. 2019.
PMID: 30837832
Free PMC article.
Review.
For example, neonatal brain injury is an important cause of developmental impairment and of permanent neurological deficits, and several types of cell death, including iron-dependent pathways, have been detected in the process of neonatal brain damage. Iron chelator …
For example, neonatal brain injury is an important cause of developmental impairment and of permanent neurological deficits, and seve …
[Erythropoietin and neuroprotection].
Arch Pediatr. 2010 Sep;17 Suppl 3:S78-84. doi: 10.1016/S0929-693X(10)70905-2.
Arch Pediatr. 2010.
PMID: 20728813
Review.
French.
This review focuses on the role of erythropoietin during the development of the CNS and its potential role as a neuroprotective agent. ...In models of hypoxia-ischemia exogenous Epo has been shown to reduce lesion size and improve structural and functi …
This review focuses on the role of erythropoietin during the development of the CNS and its potential role as a neur …
Neuroprotective Agents for Neonates with Hypoxic-Ischemic Encephalopathy.
Neonatal Netw. 2021 Nov 1;40(6):406-413. doi: 10.1891/11-T-755.
Neonatal Netw. 2021.
PMID: 34845092
Hypoxic-ischemic encephalopathy (HIE) remains a significant source of long-term neurodevelopmental impairment despite overall improvements in survival without disability in neonates who undergo therapeutic hypothermia. Each phase in the evolution of hypoxic-ischemic injury …
Hypoxic-ischemic encephalopathy (HIE) remains a significant source of long-term neurodevelopmental impairment despite overall improvements i …
Neuroprotective effects of erythropoietin against hypoxic injury via modulation of the mitogen-activated protein kinase pathway and apoptosis.
Korean J Pediatr. 2017 Jun;60(6):181-188. doi: 10.3345/kjp.2017.60.6.181. Epub 2017 Jun 22.
Korean J Pediatr. 2017.
PMID: 28690645
Free PMC article.
PURPOSE: Hypoxic-ischemic encephalopathy is a significant cause of neonatal morbidity and mortality. Erythropoietin (EPO) is emerging as a therapeutic candidate for neuroprotection. Therefore, this study was designed to determine the neuroprotective …
PURPOSE: Hypoxic-ischemic encephalopathy is a significant cause of neonatal morbidity and mortality. Erythropoietin (EPO) is …
Antioxidant Bioactive Agents for Neuroprotection Against Perinatal Brain Injury.
Cells. 2025 May 31;14(11):818. doi: 10.3390/cells14110818.
Cells. 2025.
PMID: 40497994
Free PMC article.
Review.
These neuroprotective agents have also been evaluated in clinical trials, demonstrating antioxidant effects. ...This educational review aims to provide a comprehensive overview of emerging protective strategies, including antioxidant bioactive agents a …
These neuroprotective agents have also been evaluated in clinical trials, demonstrating antioxidant effects. ...This education …
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